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A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy

burns & Trauma 2021年第1期9卷 393-400页

作者： Meifang Yin Yongming Li Yongquan Luo Mingzhou Yuan Ubaldo Armato Ilaria Dal Prà Lijun Zhang Dayong Zhang Yating Wei Guang Yang Lixian Huang Pin Wang Jun Wu Department of burn and Plastic Surgery Institute Translational MedicineThe First Affiliated Hospital of Shenzhen UniversityShenzhen Second People’s HospitalShenzhen 518035China School of Microelectronics and Communication Engineering Chongqing UniversityChongqing 400044China Institute of Fluid Physics China Academy of Engineering PhysicsMianyangSichuan 621900China Department of burn Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Human Histology&Embryology Section Department of SurgeryDentistryPediatrics&GynecologyUniversity of Verona Medical SchoolStrada Le Grazie 8Verona 37134Italy

The accurate and objective evaluation of burn depth is a significant challenge in burn wound ***,we used near infrared spectroscopy(NIRS)technology to measure the different depth of thermal burns in ex vivo porcine *** on the intensity of the spectral signals and the diffuse reflection theory,we extracted the optical parameters involved in functional(total hemoglobin andwater content)and structural(tissue scattered size and scattered particles)features that reflect the changes in burn ***,we applied support vector regression to construct a model including the optical property parameters and the burn ***,we histologically verified the burn depth data collected via *** results showed that our inversion model could achieve an average relative error of about 7.63%,while the NIRS technology diagnostic accuracy was in the range of 50μ*** the first time,this novel technique provides physicians with real-time burn depth information objectively and accurately.

关键词： burn depth Near infrared spectroscopy Support vector regression

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Endothelial progenitor cells and burn injury–exploring the relationship

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burns & Trauma 2016年第1期4卷 27-33页

作者： Derek A.Banyard Blake O.Adnani Satenik Melkumyan Cheryl Ann Araniego Alan D.Widgerow Department of Plastic Surgery Center for Tissue EngineeringUniversity of CaliforniaIrvine200S Manchester AveSte 650OrangeCA 92868USA

burn wounds result in varying degrees of soft tissue damage that are typically graded *** a key participant in neovascularization,the endothelial progenitor cel,has been the subject of intense cardiovascular research to explore whether it can serve as a biomarker for vascular *** this review,we examine the identity of the endothelial progenitor cell as well as the evidence that support its role as a key responder after burn *** there is conflicting evidence with regards to the delta of endothelial progenitor cell mobilization and burn severity,it is clear that they play an important role in wound *** and controlled studies are needed to clarify this relationship,and whether this population can serve as a biomarker for burn severity.

关键词： Endothelial progenitor cells burn depth Circulating angiogenic cells burn biomarker

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