检索结果-南通市图书馆

DETERMINATION　OF　STATES　OF　STRESS　AND　STRAIN　AT　POLE　OF　HYDRAULIC　bulge　ORTHOTROPIC　SHEET　SAMPLE

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 1995年第3期5卷 84-87页

作者： Zhou, Weixian Zhou, Xin Northwestern Polytechnical Univ Xi'an China

ＤＥＴＥＲＭＩＮＡＴＩＯＮＯＦＳＴＡＴＥＳＯＦＳＴＲＥＳＳＡＮＤＳＴＲＡＩＮＡＴＰＯＬＥＯＦＨＹＤＲＡＵＬＩＣＢＵＬＧＥＯＲＴＨＯＴＲＯＰＩＣＳＨＥＥＴＳＡＭＰＬＥ￥Ｚｈｏｕ，Ｗｅｉｘｉａｎ；Ｚｈｏｕ，Ｘｉｎ（Ｄｅｐ... 详细信息

ＤＥＴＥＲＭＩＮＡＴＩＯＮＯＦＳＴＡＴＥＳＯＦＳＴＲＥＳＳＡＮＤＳＴＲＡＩＮＡＴＰＯＬＥＯＦＨＹＤＲＡＵＬＩＣＢＵＬＧＥＯＲＴＨＯＴＲＯＰＩＣＳＨＥＥＴＳＡＭＰＬＥ￥Ｚｈｏｕ，Ｗｅｉｘｉａｎ；Ｚｈｏｕ，Ｘｉｎ（ＤｅｐａｒｔｍｅｎｔｏｆＡｅｒｏｎａｕｔ...

关键词： orthotropic sheet hydraulic bulge specimen pole stress state strain state

Dynamics of RNA with A6 bulge loop

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2002年第12期47卷 1003-1006页

作者： LIANG Chongrong & LIU CiquanKey Laboratory of Cellular & Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China Biology Department, Jinan University, Guangzhou 510630, China Key Laboratory of Cellular & Molecular Evolution Kunming Institute of Zoology Chinese Academy of Sciences Kunming China Biology Department Jinan University Guangzhou China

In order to understand the behavior of RNAs with large bulges in solution, molecular dynamics was performed on the RNA molecule in water with A6 bulge. The result of simulation showed that nonstacked conformation is the main conformation in large bulges, and the backbone of large bulge is of great conformational flexibility, but bulges-induced bends are relatively rigid. The fluctuation in bulge has little influence on the bend angle of RNAs.

关键词： RNA large bulge conformation bend angle.

Clinical study of transcatheter occlusion in treating ventricular septal defect combined with right coronary cusp bulge

在线全文

学校读者我要写书评

暂无评论

Journal of Interventional Medicine 2018年第4期1卷 205-211页

作者： Wei Ji Zhifang Zhang Wenchuo Zhao Jie Shen Lijun Fu Lin Shi Yiwei Chen Fen Li Department of Cardiology Shanghai Children's Medical Center Shanghai Jiao Tong University School of Medicine

Background: Perimembranous ventricular septal defect combined with right coronary cusp bulge generally should be treated with surgical thoracotomy, owing to the potential aortic regurgitation. However, the minimally invasive method of transcatheter closure has always attracted the attention of cardiologists and patients. The present study aimed to apply transcatheter occlusion in treating ventricular septal defect with right coronary cusp bulge and further evaluate the clinical effect through follow-up. Materials and methods: A total of 40 children diagnosed as having a ventricular septal defect with right coronary cusp bulge, examined using transthoracic echocardiography and cardiovascular angiography, were enrolled in this study. The ventricular septal defects were closed by placing occluders through transcatheter occlusion treatment. During the operation process, the children underwent angiography and transthoracic echocardiography examinations to check the position of the occlude and the extent of aortic regurgitation. The influence of occlusion on the conduction system was evaluated using a surface electrocardiogram. The children were followed up after their procedures. Results: All 40 patients were immediately and successfully occluded. Three patients with filament residual shunts were observed during the operations. No major surgical complications occurred during the perioperative period. During the follow-up period, the positions of all the occluders were good, the residual shunts in the three patients disappeared, and no new or aggravated aortic regurgitation occurred. Electrocardiogram did not reveal any atrioventricular blocks. Only one patient suffered from an incomplete right bundle branch block. Conclusions: Children diagnosed with ventricular septal defect combined with right coronary cusp bulge could be considered for transcatheter occlusion. With appropriate indications and methods, the effect may be favorable.

关键词： aortic regurgitation right coronary cusp bulge transcatheter occlusion ventricular septal defect

Isolation, Cultivation, and Morphological Characteristics of Hair Follicle Adult Stem Cells in the bulge Region in Mouse and Human

在线全文

学校读者我要写书评

暂无评论

Microscopy Research 2020年第2期8卷 9-30页

作者： Bélgica J. Molina Héctor J. Finol Center for Electron Microscopy Science Faculty Central University of Venezuela Caracas Venezuela Dermatology Service University Hospital of Caracas Caracas Venezuela

Skin contains various populations of stem cells (SCs). Among these are hair follicle stem cells (HFSCs) in the bulge region. The behavior of HFSCs deserves to be widely studied due to the benefits to be derived from their identification, isolation, and amplification. Skin samples of newborn mice (n = 32) and human adults (n = 10) were used, and the bulge region was isolated and cultured. The isolation and characterization of cells were conducted through immunocytochemistry and immunofluorescence, using mainly CD34 and CD200 monoclonal antibodies. Initially, cells grew slowly from the explant around the bulge region, accruing cells with different morphology in both mouse and human, latter being mostly polygonal;the mouse cells reaching confluence faster (5 to 7 days) than the human (12 to 15 days). It was possible to isolate into subcultures cells with small size (10 - 13 μm diameter), round-shape, scant cytoplasm, central prominent nucleus and with nucleolus, which formed colonies, maintaining their phenotype in a high proportion (77% - 83% and 91% in mouse and human, respectively), without showing changes in their morphology during almost 7 months in the mouse cells, and a month and a half in the human. These results demonstrate that the selection, the isolation, and the conditioned mediums allowed population increases of bulge cells and indicate that cultured cells may retain their sternness in that they maintained their phenotypic characteristics, expressed specific markers for SCs, and showed a high proliferative capacity for long periods. Hair follicles, in mice and humans, are important repositories of multipotent stem cells, due to their tendency to differentiate into keratinocytes. Human HFSCs, obtained by depilation, preserve their potential for proliferation and prove to be easily accessible. This suggests that the bulge cells may present an alternative source of autologous stem cells for tissue engineering and regenerative medicine.

关键词： Stem Cells Hair Follicle bulge Niche Alopecia

Identification of bulge Stem Cells in Mouse and Human Hair Follicles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microscopy Research 2018年第3期6卷 19-29页

作者： Bélgica J. Molina Elda Giansante Héctor J. Finol Center of Electron Microscopy Science Faculty Central University of Venezuela Caracas Venezuela Dermatology Service University Hospital of Caracas Caracas Venezuela

The skin contains various populaions of stem cells, but its characterization has been hampered by lack of markers and unclear location. The hair follicle has a niche for stem cells called a “bulge” which acts as a reservoir of multipotent stem cells. In the study reported here, an immunohistochemical and immunofluorescence analysis was performed on mouse and human tissues in order to determine the possible presence of stem cells of hair follicle through cytokeratin 15 (CK15), CD34, and CD200 markers identified as crucial to the stem cells and to identify the bulge region. Mouse (n = 7) and human (n = 7) skin samples were used. The expression of proteins was determined by the indirect immunoperoxidase technique and a secondary antibody bound to a fluorochrome. The specificity of staining was evaluated by negative controls. The results revealed that the stem cells associated with CD34 and CD200 antibodies were differentially expressed in the interfollicular epidermis, sebaceous glands, and bulge region, indicating that, in mice, CD34 and, in humans, CD200 are more specific than CK15 in detecting bulge cells. It also suggests that CD34 is specific for mouse bulge cells, while CD200 might have specificity for progenitor cells and partially differentiated cells in humans.

关键词： Stem Cells Hair Follicle bulge CD34 CD200

Experimental and Numerical Investigation of Cold bulge Forming of Titanium Alloy Ti55

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Mechanics 2013年第9期3卷 323-327页

作者： S. M. R. Tabatabaei M. Safari R. Shahrokh Esfahani A. Abolghasemian. Sichani M. Nourjani Pour Moghadam Department of Mechanical Engineering Amir Kabir University of Technology Tehran Iran Department of Mechanical Engineering Isfahan University of Technology Isfahan Iran Department of Mechanical Engineering Khomeinishahr Branch Islamic Azad University Isfahan Iran Department of Mechanical Engineering Razi University of Kermanshah Kermanshah Iran

In this paper, cold bulge forming of titanium alloy Ti55 was investigated. This process was done successfully and titanium alloy Ti55 was formed completely. Also, in the numerical work, this process has been investigated using Abaqus/ Explicit code. The results show that there is a good agreement between experimental and numerical results. Mechanical properties of Titanium alloy Ti55 have been investigated before and after bulge forming. The results show that mechanical properties of titanium alloy Ti55 have been improved during bulge forming. Also, hardness, and thickness variation tests of sheet metal before and after bulge forming were performed and the same results to mechanical properties were obtained.

关键词： Cold bulge Forming Titanium Alloy Ti55 Abaqus/Explicit

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

毛囊bulge细胞培养与生物学特性的研究

第三军医大学学报 2004年第16期26卷 1499-1500页

作者：张艺杨恬第三军医大学基础部细胞生物学教研室重庆400038

目的　探讨体外培养毛囊bulge细胞的生物学性质。方法　采用一步消化法 ,显微分割毛囊bulge区进行原代培养 ,观察细胞的形态特征、生长状况以及表达特性。结果　原代培养的第 2天便可见细胞生长 ,并表现出很强的增殖潜能 ,其生长期可达... 详细信息

目的　探讨体外培养毛囊bulge细胞的生物学性质。方法　采用一步消化法 ,显微分割毛囊bulge区进行原代培养 ,观察细胞的形态特征、生长状况以及表达特性。结果　原代培养的第 2天便可见细胞生长 ,并表现出很强的增殖潜能 ,其生长期可达两周以上 ;光镜下表现出原始细胞形态特征 ,培养早期细胞能强表达K19和 β1 integrin ,并随培养时间延长呈下降趋势 ;原位染色亦可见 ,K19阳性细胞集中表达于毛囊bulge区。结论　体外培养的毛囊bulge细胞在形态、生长状况和标志物表达上都表现出幼稚细胞的性质。

关键词：毛囊 bulge 培养

Inner-product of strain rate vector through direction cosine in coordinates for disk forging

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2006年第6期7卷 1320-1324页

作者：赵德文金文忠王磊刘相华 State Key Laboratory of Rolling and Automation Northeastern University

A new linear integration for plastic power was proposed.The effective strain rate for disk forging with bulge was expressed in terms of two-dimensional strain rate vector,and then its direction cosines were determined by the ratio of coordinate increments.Furthermore,inner-product of the vector for plastic power was term integrated by term and summed.Thereafter,through a formula for determination of bulge an analytical solution of stress effective factor was obtained.Finally,through compression tests,the calculated results of above formula were compared with those of Avitzur’s approximate solution and total indicator readings of the testing machine.It is indicated that the calculated compression forces are basically in agreement with the measured ones if the pass reduction is less than 13.35%.However,when the reduction gets up to 25.34% and 33.12%,the corresponding errors between the calculated and measured results also get up to 6% and 13.5%,respectively.

关键词： disk forging bulge strain rate vector direction cosine inner-product analytical solution

Finite element modeling of the shaped charge jet and design of the reusable perforating gun

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2020年第5期17卷 1389-1399页

作者： Zhao Zhang Wei-Wei Jin State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsFaculty of Vehicle Engineering and MechanicsDalian University of TechnologyDalian 116024China Institute of Manned Space System Engineering China Academy of Space TechnologyBeijing 100094China

Finite element method is used to study the formations of the penetration jet,the bulge,and the burr in the designed reusable perforating gun.The attached layer of the soft metal on the perforator is studied for the controlling of the bulge height on the casing of the reusable perforating gun.Results indicate that the shaped charge jet is initially formed in the center of the shaped charge liner and then the material of the liner is driven to the centerline of the liner by the detonation wave.The attachment of the soft metal layer to the cartridge of the perforator can be beneficial to control the bulge height.The design on the blind holes on the casing can affect the burr height formed by the collision between the jet and the casing.With the increase in the liner angle,the penetration width on the cement wall of the wellbore is increased.

关键词： Perforating gun Finite element method bulge Burr