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Clinical Efficacy Analysis of Tiotropium Bromide Combined with budesonide and formoterol Inhalation in Treating COPD

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Journal of Clinical and Nursing Research 2024年第1期8卷 1-6页

作者： Hailing Lin Yanjie Lu Qingdao Shibei District People’s Hospital Qingdao 266011Shandong ProvinceChina

Objective:To analyze the clinical efficacy of tiotropium bromide(TB)combined with budesonide formoterol(BUD/FM)inhalation in treating chronic obstructive pulmonary disease(COPD).Methods:62 COPD patients admitted to the hospital between June 2020 and December 2022 were selected as samples for this *** patients were divided into a combination group and a conventional group using the random number table method,with 31 cases in each *** patients in the combination group were treated with TB combined with BUD/FM inhalation,whereas the patients in the conventional group were treated with BUD/FM inhalation *** treatment efficacy and changes in lung function indicators of both groups were ***:The total efficacy of treatment in the combined group was higher than that in the conventional group,and the difference was statistically significant(P0.05).After three months of treatment,all lung function indicators of the combined group were higher than those of the conventional group,and the difference was statistically significant(P<0.05).Conclusion:Combining TB with BUD/FM inhalation therapy increases the efficacy of treatment for patients with ***,it also improves lung function and leads to a better prognosis.

关键词： Tiotropium bromide budesonide formoterol Inhalation therapy Chronic obstructive pulmonary disease

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Effects of Combined Inhalation of budesonide,formoterol,and Tiotropium Bromide on Arterial Blood Gas and Pulmonary Function Indexes in Patients with Chronic Obstructive Pulmonary Disease

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Journal of Clinical and Nursing Research 2023年第5期7卷 49-54页

作者： Changli Chen Ganluo County People's Hospital Liangshan Yi Autonomous Prefecture 616850Sichuan ProvinceChina

Objective:To analyze the effect of combined inhalation of budesonide formoterol and tiotropium bromide on arterial blood gas and pulmonary function indexes in patients with chronic obstructive pulmonary disease(COPD).Methods:100 patients with COPD treated from January to December 2022 were selected as observation objects,and were divided into a control group(n=50,in which budesonide and formoterol were administered)and an experimental group(n=50,the treatment drug was budesonide formoterol combined with tiotropium bromide)according to the computer grouping method,and compared the treatment ***:(i)Before treatment,there was no difference in the partial pressure of carbon dioxide and partial pressure of oxygen between the control group and the experimental group(P>0.05);after treatment,the partial pressure of carbon dioxide and partial pressure of oxygen in the experimental group were higher than those in the control group,with significant differences(P0.05);after treatment,the FVC,FEV1,and FEV1/FVC in the experimental group were significantly higher than those in the control group(P0.05);after treatment,the levels of CRP,IL-6,and TNF-αin the experimental group were lower than those in the control group,with significant differences(Pbudesonide and formoterol with tiotropium bromide has demonstrated a clear therapeutic efficacy and safety in treating chronic obstructive pulmonary ***

关键词： budesonide formoterol Tiotropium bromide Chronic obstructive pulmonary disease Arterial blood gas Lung function

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