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Clinical Study on the Prevention and Treatment of Intestinal Fibrosis in Ulcerative Colitis by moxibustion

Journal of Acupuncture and Tuina Science 2003年第2期1卷 14-17页

作者： WU Huan-gan AN Guang-qing LIU Hui-rong SHI Zheng CHEN Han-ping LIU Shi-min SHI Yin XIAO Yuan-chun Shanghai Research Center of Acupuncture and Meridian 200030 China Shanghai Research Center of Acupuncture and Meridian 200030 China Shanghai Research Center of Acupuncture and Meridian 200030 China Shanghai Research Center of Acupuncture and Meridian 200030 China Shanghai Research Center of Acupuncture and Meridian 200030 China Shanghai Research Center of Acupuncture and Meridian 200030 China Shanghai Research Center of Acupuncture and Meridian 200030 China

Objective To observe the therapeutic effects and action mechanism of moxibustion in the treatment of intestinal fibrosis in ulcerative *** Tianshu (ST25) and Qihai (CV6) were the main acupoint; other points were used according to syndrome differentiation. Sixty-five patients were randomized into two groups: Group A in which 32 cases were treated by herbpartitioned moxibustion and group B in which 33 cases were treated by bran-partitioned moxibustion. The therapeutic effects and TGF-β1, I and III collagen expressions were measured before and after *** In group A, 17 cases were cured, 12 cases improved and 3 failed; in group B, 11 cases were cured, 16 cases improved and 6 cases failed. I, III collagen expressions were obviously inhibited in the two groups, in group A in *** In the prevention and treatment of intestinal fibrosis, moxibustion may reduce the expression of TGF-β1, and hence to block or inhibit the synthesis of I, III collagens, and improve the structure and function. Key Words Colonitis - Ulcerative - Collagen - Herbpartitioned moxibustion - bran-partitioned moxibustion Foundation Item: This study supported by the National Natural Science Foundation of China, No.39970922, and Shanghai Science and Technology Committee and State Administration Bureau of Traditional Chinese MedicineTranslator: XIAO Yuan-chun

关键词： Colonitis Ulcerative Collagen Herbpartitioned moxibustion bran-partitioned moxibustion

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