检索结果-南通市图书馆

Effects of ulinastatin therapy in deep vein thrombosis prevention after brain tumor surgery:A single-center randomized controlled trial

引用

World Journal of Clinical Cases 2023年第31期11卷 7583-7592页

作者： Yun-Na Tao Qian Han Wei Jiao Li-Kun Yang Fang Wang Shan Xue Meng Shen Yu-Hai Wang Department of Neurosurgery The 904th Hospital of Joint Logistic Support ForceWuxi 214044Jiangsu ProvinceChina Nursing The 904th Hospital of Joint Logistic Support ForceWuxi 214044Jiangsu ProvinceChina

BACKGROUND Venous thromboembolism(VTE)is a common neurosurgical complication after brain tumor resection,and its prophylaxis has been widely *** are no effective drugs in the clinical management of venous thromboembolism,and there is an absence of evidence-based medicine concerning the treatment of severe multiple *** To explore whether ulinastatin(UTI)can prevent VTE after brain tumor *** The present research included patients who underwent brain tumor *** received UTIs(400,000 IU)or placebos utilizing computer-based random sequencing(in a 1:1 ratio).The primary outcome measures were the incidence of VTE,coagulation function,pulmonary emboli,liver function,renal function,and drug-related adverse *** A total of 405 patients were evaluated between January 2019 and December 2021,and 361 of these were initially enrolled in the study to form intention-to-treat,which was given UTI(n=180)or placebo(n=181)treatment in a random *** were no statistically significant differences in baseline clinical data between the two *** incidence of VTE in the UTI group was remarkably improved compared with that in the placebo *** can improve coagulation dysfunction,pulmonary emboli,liver function,and renal *** significant difference was identified between the two groups in the side effects of UTI-induced diarrhea,vomiting,hospital stays,or hospitalization *** incidence of allergies was higher in the UTI group than in the placebo *** The findings from the present research indicated that UTI can decrease the incidence of VTE and clinical outcomes of patients after brain tumor resection and has fewer adverse reactions.

关键词： Ulinastatin Venous thromboembolism brain tumor resection Randomized control trial Outcome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：