*** investigate the feasibility of magnetoencephalography(MEG)imaging in localizing sensory-motor cortex for brain tumour *** were 36patients with brain tumors in this study including 19 with meningomas,14 gliomas,2 m...
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*** investigate the feasibility of magnetoencephalography(MEG)imaging in localizing sensory-motor cortex for brain tumour *** were 36patients with brain tumors in this study including 19 with meningomas,14 gliomas,2 metastases and 1 cavernous *** the patients were taken MEG and MRI before *** individualized functional brain maps were integrated into a neuronavigation system for intraoperative *** mapping of somatosensory and/or motor cortex was performed and sites were compared before and after *** demonstrated that the tumor lesion changed the sensory-motor cortex in various degrees for the 36 *** tumors were resected completely in 34 *** surgery,neurological deficits fully recovered in 19 cases,unchanged in 15 cases,deteriorated in 2 *** was found to be practical and useful in localizing sensory-motor cortex and brain *** is a valuable non-invasive method for presurgical planning in the treatment of brain tumors.
Objective To introduce a functional image technique using resting state correlation mapping and independent component analysis (ICA) as a potential aid for presurgical planning of brain glioma resection. Methods Three...
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Objective To introduce a functional image technique using resting state correlation mapping and independent component analysis (ICA) as a potential aid for presurgical planning of brain glioma resection. Methods Three patients with brain tumors involved the motor area participated in this study. W
Objective To explore the efficacy of Vm26 combined with MeCCNU therapy for the low-grade MGMT-positive gliomas after tumor resection and *** The clinical data of 22 patients with MGMT-positive grade Ⅱ gliomas who und...
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Objective To explore the efficacy of Vm26 combined with MeCCNU therapy for the low-grade MGMT-positive gliomas after tumor resection and *** The clinical data of 22 patients with MGMT-positive grade Ⅱ gliomas who underwent total removal of tumors with enhanced MRI imaging showing no residual tumors in the neurosurgery of the first affiliated hospital of Soochow university from Jan 2005 to Oct 2008 were analyzed retrospectively.10 cases of all 22 patients are diffuse astrocytomas;3 cases are oligodendrogliomas;5 cases are mixed oligo-astrocytomas and 4 cases are *** patients received three-dimensional conformal radiotherapy 2~4 weeks after surgery with radiation field including areas 1~2cm away from the edge of cavity after tumor resection according to brain imaging and exposure dose being 50~55Gy/6~7weeks.2 weeks after the end of radiotherapy,these patients underwent Vm26 combined with MeCCNU therapy(Vm26:50mg/m2/day,intravenous dripping for 3 days,repeated after 8 weeks for 3 cycles;MeCCNU:50mg/m2/day,taken orally for 3 days,repeated after 8 weeks for 4 cycles) with MRI scanning *** 6 cases of 22 MGMT-positive grade Ⅱ gliomas are positive for both TopoⅡα and Pgp;10 cases and 2 cases are only positive for TopoⅡα and Pgp,respectively;and 4 cases are negative for both TopoⅡα and Pgp.22 patients were followed up for 2~5 years and tumors recurred in 6 cases with average time of recurrence being 16.6 months;CT or MRI imaging showed no tumor recurrence in 13 cases;3 cases underwent the second surgery due to MRI imaging showing possible tumor recurrence 2 years after prior surgery;however,pathological examination reported suspected recurring tumor was necrotic *** these 22 patients,1-year survival rate was 100% and 2-year survival rate was 88.9%.Conclusion Vm26 combined with MeCCNU chemotherapy is able to efficaciously inhibit the growth of gliomas,have little side-effects,and is a safe and effective therapeutic alternative
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