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Prophylactic supplementation of microencapsulated boswellia serrata and probiotic bacteria in metabolic syndrome rats

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Food Bioscience 2023年第1期51卷 1016-1027页

作者： Moetazza M.Alshafei Ahmed M.Mabrouk Emtenan M.Hanafi Manal M.Ramadan Reda M.S.Korany Seham S.Kassem Dina Mostafa Mohammed Nutrition and Food Science Department National Research CentreDokkiGizaEgypt Dairy Department National Research CentreDokkiGizaEgypt Animal Reproduction and AI Department National Research CentreDokkiGizaEgypt Chemistry of Flavor and Aroma Department National Research CentreDokkiGizaEgypt Pathology Department Faculty of Veterinary MedicineCairo UniversityGizaEgypt

Metabolic syndrome(MeS)is a major health problem associated with the high prevalence of obesity,diabetes,hypertension and *** serrata resin(BS)is an old remedy reputed by its rich antioxidant *** present research aimed to assess the impact of microencapsulated BS if given in combination with probiotic bacteria(BAC)(Lactobacillus plantarum and Lactobacillus rhamnosus)which had anti-inflammatory and antioxidant activities to control the metabolic disorders associated with *** extract of BS was prepared,total phenolic,total antioxidants and HPLC were *** extract was microencapsulated by spray drier and the microcapsules were *** were suspended in MRS,cultivated and microencapsulated by freeze *** were randomly assigned to 5 groups(8/gp).The 1st group was negative control receiving basic diet(C),the 2nd group was positive control fed on HFD,the 3rd group was fed on HFD+BS(400 mg/kg),the 4th group was fed on HFD+BAC(1 ml containing 1011 CFU),the 5th group was fed on HFD+BS+*** 8 weeks animals were sacrificed,the collected serum was analyzed for different biochemical *** body organs and body fat weights were estimated and histopathological and immunohistochemical examinations were *** showed the ability of BS in controlling most of the parameters related to MeS and improvement of histopathology findings in *** and BAC acted in synergy in this *** conclusion,microencapsulated BS or its combination with Probiotic bacteria may control MeS and both acted as symbiotic in augmenting the improvement of MeS intact model.

关键词： Metabolic syndrome boswellia serrate Probiotic bacteria Micro-encapsulation Liver steatosis

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