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Evaluation of biological effects of three neodymium compounds on silkworm,Bombyx mori

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Journal of Rare Earths 2021年第10期39卷 1289-1299,I0005页

作者： Vivian Andoh Huaiyang Guan Lin Ma Weiguo Zhao Long Li Guohua Wu College of Biotechnology Jiangsu University of Science and TechnologyZhenjiang 212018China The Sericultural Research Institute Chinese Academy of Agricultural SciencesZhenjiang 212018China

Neodymium(Nd)is one of the most famous members of rare earth elements *** the increasing global demand for Nd,it can inevitably enter the environment and affect the ecological environment through the food chain and other ***,it is very important to study the biological effects of *** this study,the biological effects of 3 kinds of Nd compounds,*** oxide(Nd_(2)O_(3)),neodymium chloride(NdCl3)and neodymium nitrate(Nd(NO_(3))_(3)),were evaluated by using silkworm models through the method of intravascular *** of the three Nd compounds was prepared into 6 groups at different concentrations(40,50,60,70,80,90μg/μL).The results show that within the certain concentration range,Nd compounds show great damage to the growth of silkworms since high death rate is observed:the death rate from Nd2 O3 group is floating between 30%and 80%,the one from NdCl3 group is between 17%and 33%and that from Nd(NO3)3 group is between 23%and 37%.It also reveals that Nd compounds have some negative effects on the body length and weight of ***,the histophysiological study shows that the three Nd compounds cause no obvious negative effects on the cell morphologies in midgut,fat body and silk *** XRD and FTIR spectra show that the secondary and the crystalline structures of silks are not destroyed,the TGA and DTG data exhibit that the thermal stability of silks is not damaged,and the tensile test shows that the mechanical properties of silks are not affected significantly by the intake of Nd *** general,the intake of Nd compounds has significant inhibitory effects on silkworm growth but little negative impact on silk structures or cell morphology,the study can provide useful toxicological data for the safe application of Nd compounds in various fields.

关键词： Nd compounds Bombyx mori Model animal biological effects Rare earths

Establishment of injury models in studies of biological effects induced by microwave radiation

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Military Medical Research 2021年第2期8卷 253-272页

作者： Yun-Fei Lai Hao-Yu Wang Rui-Yun Peng Beijing Institute of Radiation Medicine Beijing 100850China

Microwave radiation has been widely used in various fields,such as communication,industry,medical treatment,and military *** radiation may cause injuries to both the structures and functions of various organs,such as the brain,heart,reproductive organs,and endocrine organs,which endanger human ***,it is both theoretically and clinically important to conduct studies on the biological effects induced by microwave *** successful establishment of injury models is of great importance to the reliability and reproducibility of these *** this article,we review the microwave exposure conditions,subjects used to establish injury models,the methods used for the assessment of the injuries,and the indicators implemented to evaluate the success of injury model establishment in studies on biological effects induced by microwave radiation.

关键词： Microwave radiation Injury model biological effects Methods biological indicators Review

Cycloartenol triterpenoid saponins from Cimicifuga simplex(Ranunculaceae) and their biological effects

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Chinese Journal of Natural Medicines 2015年第2期13卷 81-89页

作者： WU Lun CHEN Zhi-Li SU Yang WANG Qiu-Hong KUANG Hai-Xue Key Laboratory of Chinese Materia Medica Heilongjiang University of Chinese Medicine Ministry of Education

The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9,19-cyclolanostane triterpenoid glycosides, which are distributed widely in Cimicifuga plants, but not in other members of the Ranunculaceae family, and are considered to be characteristics of the Cimicifuga genus. This type of triterpenoid glycoside possesses several important biological activities. More than 120 cycloartane triterpene glycosides have been isolated from Cimicifuga simplex Wormsk. The aim of this review article is to summarize all the major findings based on the available scientific literatures on C. simplex, with a focus on the identified 9,19-cyclolanostane triterpenoid glycosides. biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed.

关键词： Cimicifuga simplex Ranunculaceae Cycloartenol triterpenoid saponins biological effects

Size-dependent biological effects on Vascular Endothelial Cells Induced by Different Particulate Matters

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2014年第3期34卷 314-321页

作者：程文娟荣怿史廷明周婷刘跃伟陈卫红 Department of Occupational and Environmental Health MOE Key Lab of Environment and Health School of Public Health Tongji Medical College Huazhong University of Science and Technology Nanchang Center for Disease Control and Prevention Hubei Center for Disease Control and Prevention

Summary： The contribution of particles to cardiovascular mortality and morbidity has been enlightened by epidemiologic and experimental studies. However, adverse biological effects of the particles with different sizes on cardiovascular cells have not been well recognized. In this study, sub-cultured human umbilical vein endothelial cells （HUVECs） were exposed to increasing concentrations of pure quartz particles （DQ） of three sizes （DQPM1, 〈1 μm; DQPM3-5, 3-5 μm; DQPM5, 5 μm） and carbon black particles of two sizes （CB0.1, 〈0.1 μm; CB 1, 〈 1 μm） for 24 h. Cytotoxicity was estimated by measuring the activity of lactate dehydrogenase （LDH） and cell viability. Nitric oxide （NO） generation and cyto- kines （TNF-α and IL-1β） releases were analyzed by using NO assay and enzyme-linked immunoabsorbent assay （ELISA）, respectively. It was found that both particles induced adverse biological effects on HUVECs in a dose-dependent manner. The size of particle directly influenced the biological activity. For quartz, the smaller particles induced stronger cytotoxicity and higher levels of cytokine responses than those particles of big size. For carbon black particles, CB0.1 was more capable of inducing adverse responses on HUVECs than CB 1 only at lower particle concentrations, in contrast to those at higher concentrations. Meanwhile, our data also revealed that quartz particles performed stronger cell damage and produced higher levels of TNF-α than carbon black particles, even if particles size was similar. In conclusion, particle size as well as particle composition should be both considered in assessing vascular endothelial cells injury and inflammation responses induced by particles.

关键词： particles vascular endothelial cells biological effects size-dependent

biological effects and mechanisms of shortwave radiation： a review

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Military Medical Research 2018年第1期5卷 79-84页

作者： Chao Yu Rui-Yun Peng Beijing Institute of Radiation Medicine Beijing 100850 China

With the increasing knowledge of shortwave radiation,it is widely used in wireless communications,radar observations,industrial manufacturing,and medical *** of the benefits from shortwave,these wide applications expose humans to the risk of shortwave electromagnetic radiation,which is alleged to cause potential damage to biological *** review focused on the exposure to shortwave electromagnetic radiation,considering in vitro,in vivo and epidemiological results that have provided insight into the biological effects and mechanisms of ***,some protective measures and suggestions are discussed here in the hope of obtaining more benefits from shortwave with fewer health risks.

关键词： Shortwave Electromagnetic radiation biological effects

biological effects of Sunflower Seeds Implanted by Carbon Ion

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Agricultural Biotechnology 2013年第3期2卷 12-17页

作者： Huan YANG Yang WANG Lixian HE Fang JIN Fengshou ZHANG Tao ZHANG Ying SU Mulan LIAN Yunlong ZHOU College of Life Science Beijing Normal University College of Nuclear Science and Technology Beijing Normal University Key Laboratory of Beam Technology and Material Modification of Ministry of Education Beijing Normal University

[ Objective ] This study aimed to investigate the effects of carbon ion implantation and implantation times on growth and genetic variation of sunflowers. [ Method] Carbon ions were implanted into Bakui 138, Bakui i36 and Bakui 118 seeds at dose of 5 - 10is C/cm2, before they were planted. Their Fl-generation seeds were irradiated again. Seeds of the both generations were planted and the growth d the seedlings was observed in field tests. Finally, their genetic variation was analyzed through RAPD. [ Result] The germination rate and several agronomic traits like plant height, stem diameter, leaf number and yields of Bakui 138 of once-irradiated group were significantly improved, while that of twice-irradiated group showed opposite trend. The variation of Bakui 136 and Bakui 118 was insig- nificant. At the molecular level, the genetic distance with the control group of once and twice-irradiated groups was 0. 111 1, 0. 108 7 in Bakui 138; 0. 068 O, O. 030 3 in Bakui 136 and 0.062 5,0.043 5 in Bakui 118. [Conclusion] Carbon ion implantation had a significant effect on the growth and development of Bakui 138, and the effect varied with irradiation times. Moreover, it caused genomic variation in the three sunflower cuhivars.

关键词： Carbon ion implantation biological effects RAPD Sunflower

Impact of Fertilizer Types on Photosynthetic and biological effects of Direct-seeded Brassica napus at Flowering Stage

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Agricultural Science & Technology 2012年第3期13卷 554-557页

作者：李俊余常兵张春雷余利平程雨贵李玲马霓中国农业科学院油料作物研究所农业部油料作物生物学与遗传育种重点实验室农业部作物生理生态与栽培重点开放实验室湖北武汉430062 宜昌市农业科学院湖北宜昌443202

[Objective] The aim was to investigate the effects of fertilizer type on di- rect-seeded rapeseed and to explore effective fertilizing. [Method] Four treatments including different types of fertilizers were set in the test. Growth, photosynthesis and chlorophyll fluorescence parameters at flowering stage such as plant height, stem diameter, shoot and root dry matter, net photosynthesis, light energy conversion effi- ciency （Fv/Fm） and SPAD value, were investigated. The effects of fertilizer treat-ments on the yield of rapeseed were evaluated as well. [Result] Both multi-functional fertilizer and controlled release fertilizer could improve plant height, stem diameter, shoot dry matter, SPAD value, net photosynthesis, non-photochemical quenching （NPQ）, etc., which helped increase yield and stress resistance. [Conclusion] Both multi-functional fertilizer and controlled release fertilizer could improve yield significantly while multi-functional fertilizer （MFF） was better than controlled release fertilizer （CRF）.

关键词： Fertilizer type Photosynthesis biological effects Brassica napus

Photochemistry and pharmacology of 9,19-cyclolanostane glycosides isolated from genus Cimicifuga

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Chinese Journal of Natural Medicines 2016年第10期14卷 721-731页

作者： SU Yang CHI Wen-Cheng WU Lun WANG Qiu-Hong KUANG Hai-Xue Department of Microbiology Immunology&Molecular GeneticsUniversity of California Los AngelesLos AngelesCA 90025USA Key Laboratory of Chinese Materia Medica Department of PharmacologyHeilongjiang University of Chinese MedicineHarbin 150040China The University of Sydney NSW 2006Australia

The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9, 19-cyclolanostane triterpenoid glycosides, which often exhibit extensive pharmacological activities. 9, 19-Cyclolanostane triterpenoid glycosides are distributed widely in genus Cimicifuga rather than in other members of the Ranunculaceae family. So far, more than 140 cycloartane triterpene glycosides have been isolated from Cimicifuga spp.. The aim of this review was to summarize all 9, 19-cyclolanostane triterpenoid glycosides based on the available relevant scientific literatures from 2000 to 2014. biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed.

关键词： Cimicifuga spp 9,19-Cyclolanostane glycosides Chemical structure biological effects

effects of Nano-TiO2 on Chlamydomonas reinhardtii Cell Surface under UV,Natural Light Conditions

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Journal of Wuhan University of Technology(Materials Science) 2017年第1期32卷 217-222页

作者：陈小娟 LU Ruirui 刘鹏 LI Xi Key Laboratory of Ecological Impacts of Hydraulic-Projects and of Aquatic Ecosystem of Ministry of Water Resources Institute of HydroecologyMinistry of Water Resources and Chinese Academy of SciencesWuhan 430079China Department of Chemistry School of SciencesWuhan University of TechnologyWuhan 430070China

Cell surface of aquatic organisms constitutes a primary site for the interaction and a barrier for the nano-TiO2 biological *** the present study,the biological effects of nano-TiO2 on a unicellular green algae Chlamydomonas reinhardtii were studied by observing the changes of the cell surface morphology and functional groups under UV or natural *** SEM,the cell surface morphology of *** was changed under UV light,nano-TiO2 with UV light or natural light,which indicated that photocatalysis damaged cell *** was also observed that cell surface was surrounded by TiO2 *** ATR-FTIR spectra showed that the peaks of functional groups such as C-N,-C=O,-C-O-C and P=O,which were the important components of cell wall and membrane,were all depressed by the photocatalysis of nano-TiO2 under UV light or natural *** photocatalysis of nano-TiO2 promoted peroxidation of functional groups on the surface of *** cells,which led to the damages of cell wall and membrane.

关键词： nano-TiO2 Chlamydomonas reinhardtii biological effects cell surface morphology functional groups