检索结果-南通市图书馆

Influence of coronary bifurcation angle on atherosclerosis

Acta Mechanica Sinica 2019年第6期35卷 1269-1278页

作者： Zhaomiao Liu Shengwei Zhao Yunjie Li Feng Shen Yipeng Qi Qi Wang College of Mechanical Engineering and Applied Electronics Technology Beijing University of TechnologyBeijing 100124China Department of Cardiology PLA General HospitalBeijing 100853China

Hemodynamics plays a crucial role in the development and progression of coronary atherosclerosis,which is prone to occur in branch bifurcation.A n individual aortic-coronary artery model and three changed bifurcation angle models are constructed by Mimics and Freeform based on computed tomography *** influence of different coronary bifurcation angles between left main(LM),left anterior descending(LAD),and left circumflex(LCX)on the blood flow field and related hemodynamic parameters are *** is shown that a wider bifurcation angle between LAD and LCX can cause a wider low-wall shear stress area,leading to ***,a decreased angle between LM and LAD is predisposed to prevent *** results help to better understand the hemodynamic causes of atherosclerosis with various bifurcation angles in coronary arteries and to provide guidance for clinical assessment and prevention.

关键词： Atherosclerosis Coronary artery bifurcation angle Hemodynamics Wall shear stress

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Coronary bifurcation angle from 3-D predicts clinical outcomes after stenting bifurcation lesions

引用

Chinese Medical Journal 2012年第12期125卷 2083-2088页

作者： CHEN Shao-liang Teguh Santoso ZHANG Jun-jie YE Fei XU Ya-wei FU Qiang KAN Jing Chitprapai Paiboon ZHOU Yong DING Shi-qing Tak W Kwan Department of Cardiology Nanjing First Hospital NanjingMedical University Nanjing Jiangsu 210006 China Department of Cardiology Medistra Hospital University ofIndonesia Medical School Jakarta Indonesia Department of Cardiology Shanghai 10th People＇s HospitalShanghai 200072 China Department of Cardiology Xuzhou Central Hospital XuzhouJiangsu 221009 China Department of Cardiology Bangkok General Hospital BangkokThailand Department of Cardiology Zhangjiagang People＇s HospitalZhangjiagang Jiangsu 215600 China Department of Cardiology Huainan Xinhua Hospital HuainanAnhui 232038 China Department of Cardiology Beth Israel Hospital NewYork USA

Background The predictive value of bifurcation angle （BA） for worse events after stenting bifurcation lesions remains to be unknown. The present study was to investigate the dynamic change of BA and clinical relevance for patients with coronary bifurcation lesions treated by drug-eluting stent （DES）. Methods BA was calculated by 3-D quantitative coronary analysis from 347 patients in DKCRUSH-II study. Primary endpoint was the occurrence of composite major adverse cardiac events （MACE） at 12-month, including cardiac death, myocardial infarction （MI） and target vessel revascularization （TVR）. Secondary end points were the rate of binary restenosis and stent thrombosis at 12-month. Results Stenting was associated with the reduction of distal BA. The cut-off value of distal BA for predicting MACE was 60°. Distal BA in 〈60° group had less reduction after stenting （（-1.96＋13.58）°vs. （-12.12±23.58）°, P 〈0.001）; two-stent technique was associated with significant reduction of distal BA （△（-4.05±14.20）°）, compared to single stent group （4＋1.55±11.73, P=0.003）; the target lesion revascularization （TLR）, TVR and MACE rate was higher in one-stent group （16.5%, 19.0% and 21.5%）, compared to two-stent group （3.8%, P=0.002; 7.5%, P=0.016; and 9.8%, P=0.024）, respectively. Among patients in ≥60° group, there were no significant differences in distal BA, stent thrombosis （ST）, MI, MACE, death, TLR, TVR between one- and two-stent groups; after stenting procedure, there was only slight change of distal BA in left anterior descending （LAD）-Ieft circumflex （LCX） subgroup （from （88.54±21.33）° at baseline to （82.44±31.72）° post-stenting）, compared to either LAD-diagonal branch （Di）, or LCX-obtuse marginal branch （OM）, or IRCA distal （RCAd）（all P 〈0.001 ）. Conclusion Two-stent technique was associated with significant reduction of distal BA. DK crush stenting had reduced rate of MACE in patients in 〈60° group, compared to one-stent technique.

关键词： coronary bifurcation lesions bifurcation angle major adverse cardiac events ROC curve

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of coronary bifurcation angle on clinical outcomes in Chinese patients treated with crush stenting： a subgroup analysis from DKCRUSH-1 bifurcation study

引用

Chinese Medical Journal 2009年第4期122卷 396-402页

作者： CHEN Shao-liang ZHANG Jun-jie YE Fei CHEN Yun-dai FANG Wei-yi WEI Meng HE Ben SUN Xue-wen YANG Song CHEN Jin-guo SHAN Shou-jie TIAN Nai-liang LI Xiao-bo LIU Zhi-zhong KAN Jing Lee Michael Kwan Tak W Nanjing First Hospital Nanjing Medical University NanjingJiangsu 210006 China Department of Cardiology Beijing Anzhen Hospital CapitalMedical University Beijing 100029 China Department of Cardiology Shanghai Chest Hospital Shanghai 200030 China Department of Cardiology Shanghai Sixth Hospital Shanghai JiaoTong University School of Medicine Shanghai 200233 China Department of Cardiology Shanghai Renji Hospital Shanghai JiaoTong University School of Medicine Shanghai 200001 China Queen Mary Hospital Hongkong China Beth Israel Medical Center New York USA

Background bifurcation angles may have an impact on the clinical outcomes of crush stenting. We sought to compare high （≥60°） with low （〈60°） bifurcation angle in patients who underwent either classical or double kissing （DK） crush stenting for bifurcation lesions from the DKCRUSH-1 data base. Methods There were 212 patients with 220 lesions, some with low-angle （n=138） and some with high-angle （n=74）. Angiography was indexed at 8-month after procedure. Primary endpoint was the occurrence of major adverse cardiac events （MACEs）, defined as cardiac death, myocardial infarction and target lesion revascularization （TLR）. Secondary endpoint included late lumen loss, the rate of restenosis, and final kissing balloon inflation （FKBI）. Results At 8 months, clinical follow-up was 100%; angiographic follow-up was 75% in the low-angle group and 83.3% in the high-angle group. There were no significant differences in the FKBI between the high-angle group （91.43%） and the low-angle group （82.39%）. In the high angle group, there was a significant difference in contrast volume used （P=0.005） but no significant difference in acute gain, minimum lumen diameter （MLD）, late loss and diameter stenosis in the pre-bifurcation segment, post-bifurcation segment or side branch. When lesions were assigned into with- （n=-133） and without-FKBI （n=42）, significant side-branch late loss was seen in the group without-FKBI （（0.65±0.49） mm vs （0.47±0.62） mm, P=0.02）, with a resultant greater restenosis rate （37.68% vs 18.32%, P=0.001）. No difference was detected in the MACE free survival rate between the high and low angle groups （82.39% vs 82.36%, P=0.84）. The rate of stent thrombosis tended to be higher in the lower-angle group although there was no significant difference （P=0.38）. The TLR free survival rate was 87.2% in the with-FKBI group vs 73.5% in the without-FKBI group （P=0.001）. Cox regression analysis showed that the independent predictors for target vessel revascularization were the

关键词： coronary bifurcation angle double kissing crush stenting

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Importance of bifurcation angle in bifurcation stenting

引用

Chinese Medical Journal 2012年第22期125卷 4122-4125页

作者： Dobrin Vassilev Alexander Alexandrov Dan Le Katrina Nguyen James Nguyen Hung Phan Robert J. Gil Cardiac Catheterization Laboratory National Heart HospitalSofiaBulgaria"Medikacor"Heart HospitalRuseBulgaria Cardiac Catheterization Laboratory National Heart HospitalSofiaBulgaria Heart Failure Program the University of Alabama in Birmingham(UAB)BirminghamAlabamaUSA University of California at San Diego San DiegoCaliforniaUSA The University of Arizona Medical Center TucsonArizonaUSA Department of Medicine Weiss Memorial HospitalChicago IllinoisUSA Central Clinical Hospital of the Internal Affairs and Administration Ministry WarsawPolandInstitute of Experimental and Practical MedicinePolish Academy of ScienceWarsawPoland

bifurcation coronary lesions are relatively frequent in today＇s interventional cardiology practice, averaging between 10%-15% of all interventions （PCIs）. Several percutaneous coronary problems inherent in the treatment of bifurcation lesions are periprocedural side branch （SB） compromise （composite of SB closure or appearance of significant ostial stenosis after main vessel （MV） stenting causing ischemia） frequently related to periprocedural myonecrosis,

关键词： bifurcation angle stenting

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：