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The bethesda system for Reporting Thyroid Cytopathology(TBSRTC):A report of 2,781 cases in a Chinese population

Chinese Journal of Cancer Research 2020年第2期32卷 140-148页

作者： Yanli Zhu Yuntao Song Guohui Xu Zhihui Fan Wenhao Ren Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of PathologyPeking University Cancer Hospital and InstituteBeijing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Head and Neck SurgeryPeking University Cancer Hospital and InstituteBeijing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of UltrasoundPeking University Cancer Hospital and InstituteBeijing 100142China

Objective:To evaluate the diagnostic utility of The bethesda system for Reporting Thyroid Cytology(TBSRTC)at Peking University Cancer Hospital,the incidence of noninvasive follicular thyroid neoplasms with papillary-like nuclear features(NIFTP),and the impact of reclassification on cytopathological ***:We performed a retrospective study of thyroid fine-needle aspiration(FNA)cases between April 2014 and March *** FNA results were classified according to ***-surgery histological findings were followed ***:A total of 2,781 thyroid FNAs were *** incidences of the 6 diagnostic categories(DCs I-VI)were 14.8%,17.1%,15.8%,2.3%,11.6%and 38.5%,respectively.A total of 1,122 patients(40.3%)had corresponding histological *** accounted for 0.4%of papillary thyroid carcinoma(PTC)cases,and there was no significant difference in the risk of malignancy(ROM)for each TBSRTC DC between"NIFTP=carcinoma(Ca)"and"NIFTP≠Ca".When"NIFTP=Ca",the sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),and accuracy of TBSRTC were 98.0%,84.0%,99.4%,58.3%,and97.5%,***"NIFTP≠Ca",the sensitivity,specificity,PPV,NPV and accuracy of the TBSRTC were 98.1%,81.5%,99.3%,61.1%,and 97.5%,***:TBSRTC is effective in the preoperative diagnosis of thyroid nodules in Peking University Cancer *** impact of the reclassification of NIFTP on cytopathological outcomes is limited because of its low incidence,and the revised ROMs are not suitable for Asian patients.

关键词： bethesda system thyroid FNA cytopathology NIFTP

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Study of Prevalence of Abnormal Cervical Cytology in Al-Shatby Maternity University Hospital

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Open Journal of Obstetrics and Gynecology 2021年第4期11卷 434-449页

作者： Ahmed Essmat Mahmoud Meleis Hossam Elsokkary Sanna Shawky Ahmed Enas El-Soody Department of Obstetrics and Gynecology Faculty of Medicine Alexandria University Alexandria Egypt Department of Pathology Medical Research Institute Alexandria University Alexandria Egypt

Introduction: Cervical cancer is the most common cause of preventable cancer related deaths;cervical cancer has a long pervasive phase (cervical dysplasia);the prevalence of cervical dysplasia varies according to the socioeconomic characteristics and geographic areas of the population studied. Low-grade lesions regress spontaneously in a significant number of patients, while high grade lesions will progress to an invasive cancer if left untreated. Cervical cancer screening is an important component of the World Health Organization (WHO) strategy for combating cervical cancer. The incidence and prevalence of cervical cancer has reduced remarkably over the last three decades in developed countries where there are effective, well-coordinated screening programs, and treatment of cervical dysplasia, while in developing countries it has been increasing and has constituted major health problems among women where there are no well-coordinated and effective screening programs, also resources are very low and no insurance can cover this programs. Aim of the work: The aim is to assess the prevalence of abnormal cervical cytology in Al Shatby Maternity University Hospital patients using Pap smear. Materials and methods: Inclusion criteria: 1) Married woman from 3 years or more;2) Women age from 21 to age 65 years. Exclusion criteria: 1) Previously known cervical cancer patient;2) Virgin females;3) Woman with active vaginal bleeding. Results: 83% of patients were -ve intraepithelial neoplasia {37.7% was normal cytology and 45.3% was inflammatory}. 17% was +ve intraepithelial neoplasia (abnormal cytology), {11.1% ASCUS, 2.9% LSIL, 1.3% HSIL, 1.1% ASC-H, 0.3% AGS

关键词： Abnormal Cervical Cytology bethesda system Cervical Cancer Screening Pap Smear Preinvasive Cervical Cancer

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