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A Study of the Cytotoxicity of a New Nonwoven Polymeric Fibrous bandaging Material In-Vitro

Journal of Biomaterials and Nanobiotechnology 2011年第3期2卷 234-238页

作者： A.M. Dygai L.M. Ogorodova S.G. Psakhie Y.P. Belsky N.V. Belska M.G. Danilets A.A. Ligatcheva A.A. Сhurin 不详

Traditionally used cotton-based bandaging materials have several disadvantages which can be overcome by using another fabric structure – nonwoven fabric. Moreover, these materials are more spongeous which increases their sorption capacity. The new bandaging material developed by the Institute of Physics of Strength and Material Science of the Siberian Branch of the Russian Academy of Sciences has even better sorption capacity with improved sorption properties. Its sorption capacity has been increased by means of an additional introduction of porous aluminum hydrate particles into fabric. It is important that a bandaging material has a good biocompatibility and does not have any cytotoxic effect on cells and tissues. Here it is present results of the study of the material's direct contact and indirect cytotoxicity assays in comparison with cotton gauze. It have found that in the direct contact of nonwoven polymeric fibrous bandaging material (NPFBM) with cells for 24 hours of cultivation no changes in cell morphology take place, nor does the amount of dead cells increase. These conclusions have been made by means of both a visual examination and an МТТ assay. The NPFBM extract did not have any cytotoxic effect on the tested cells either. The obtained results allow us to make a conclusion that the NPFBM complies with the international standard ISO 10993-5, which is applied to medical goods, and can from now on be applied in the treatment of infected wounds in clinical practice.

关键词： cytotoxicity bandaging materials development of biocompatible biomaterials

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Geometry of the bandaging procedure and its application while wrapping bandages for treatment of leg ulcers

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Journal of Biomedical Science and Engineering 2013年第12期6卷 1186-1190页

作者： Monica Puri Sikka Subrato Ghosh Arunangshu Mukhopadhyay Department of Textile Technology National Institute of Technology Jalandhar India

Appropriate compression bandaging is important for compression therapeutic medical diseases. The high compression approach employed for treating venous leg ulcers should be used correctly so that sufficient (but not excessive) pressure is applied. Bandages used to treat venous disease by compression should achieve and sustain effective levels and gradients of pressure and minimize the risk of pressure trauma. To maintain graduated compression on the limb, the bandage needs to be applied at the same tension for each layer from the ankle to the knee. In this paper, the geometry for various bandaging procedures is used to wrap each layer of bandage by marking the relaxed length of the bandage. The relaxed length is calculated depending on the stretch%, the average circumference of the limb to which it is to be applied and the bandaging technique to be used. This paper aims at developing a scientific approach while applying the bandage to reduce the inter operator variability in applying the same tension on each successive layer of bandage.

关键词： bandaging Compression Inter Operator Variability Graduated Relaxed Length Stretch

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