检索结果-南通市图书馆

Anthrax Biomarker:a Fluorescent Probe for Dipicolinic Acid Using Eu(Ⅲ)-doped Nanosheets

Chinese Journal of Structural Chemistry 2020年第10期39卷 1788-1794,1742页

作者： WANG Bing WU Qiong XIA JIN-Feng LI Xin JIANG Dan-Yu LI Qiang School of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200062China Department of Chemistry Hebei Normal University for NationalitiesChengdeHebei 067000China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050China

A novel two-dimensional nanosheet fluorescent probe embedded with rare earth Eu(Ⅲ)was developed to detect dipicolinic acid(DPA),a biomarker of Bacillus anthracis bacterial ***,a major component of Bacillus anthracis spores which were highly toxic to humans,was not found in other common *** ability to detect ultra-low concentrations of DPA would therefore be of great ***(Ⅲ)-doped ytterbium hydroxide nanosheets were obtained by mechanical exfoliation from layered rare-earth hydroxide(LRH)*** crystallinities,layered structure and morphology of the as-synthesized nanosheets were studied by power X-ray diffraction,transmission electron microscopy and atomic force ***(Ⅲ)emission increased linearly with DPA addition in the range of 0.1~30μmol/*** on the antenna effect,the detection limit of DPA was 0.078μmol/L and much lower than the infective dose of Bacillus anthracis in humans of 60μmol/*** nanosheet fluorescent probe exhibited good specificity toward DPA,and the interferences with selected aromatic ligands and amino acids were observed to be negligibly small in comparison with that of *** findings provide a basis for the application of Eu(Ⅲ)-doped nanosheets for accurate,sensitive,and selective monitoring of DPA as a biomarker of anthrax.

关键词： layered compound nanosheets fluorescent probe dipicolinic acid bacterial spores

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Enhanced Sporicidal Activity of Alcohol and Epigallocatechin-Palmitate-Based Hand Hygiene Formulations Comprised of Plant-Derived Compounds

引用

Journal of Biosciences and Medicines 2020年第6期8卷 89-99页

作者： Tinchun Chu Lee H. Lee Ayuni Yussof Sabrina Lopez Gabriela Herrera Priscilla Luna Mahfuza Uddin Laying Wu John A. Murzaku Douglas Dickinson Stephen Hsu Department of Biological Sciences Seton Hall University South Orange NJ USA Department of Biology Montclair State University Montclair NJ USA Microscopy and Microanalysis Research Laboratory Montclair State University Montclair NJ USA Department of Mathematics and Computer Science Seton Hall University South Orange NJ USA Camellix Research Laboratory Augusta GA USA Department of Oral Biology & Diagnostic Sciences Augusta University Augusta GA USA

Pathogenic spore-forming bacteria pose high risks to healthcare settings, as well as in the food and beverage industries. We reported recently that novel alcohol-based formulations containing plant-derived compounds, including epigallocatechin-3-gallate-palmitate (EGCG-P), a green tea polyphenol ester, provide > 99.99% inactivation of bacterial spores within 60 sec. Based on recently published data from our group and others, we hypothesize that a combination of EGCG-P and alcohol formulated with other plant-derived ingredients would achieve high sporicidal efficacy against a wide spectrum of bacterial spores and can provide novel hand hygiene methods against bacterial spores without toxicity. The objectives of the current study were to optimize two novel formulations with combinations of glycerol, citric acid, and EGCG-P to increase sporicidal activity and explore the rapid inactivation mechanisms and suitability for sporicidal products with broad-spectrum activities against aerobic and anaerobic bacterial spores. Methods included suspension testing of two formulations against spores from Bacillus cereus and Clostridium sporogenes, quantification of spore germination, and scanning electron microscopy. The results demonstrated that these novel formulations were able to reduce spore germination by >99.999% after 30 sec exposure in suspension tests, and rapidly caused physical damage to the spores. Additional

关键词： Alcohol Hand Hygiene Sporicidal bacterial spores Plant-Derived Compounds

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：