检索结果-南通市图书馆

Intravesical bacillus calmette-guerin(BCG)in treating non-muscle invasive bladder cancer—analysis of adverse effects and effectiveness of two strains of BCG(Danish 1331 and Moscow-I)

引用

Asian Journal of Urology 2022年第2期9卷 157-164页

作者： Yuvaraja B.Thyavihally Preetham Dev Santosh Waigankar Abhinav Pednekar Nevitha Athikari Abhijit Raut Archan Khandekar Naresh Badlani Ashishkumar Asari Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute Andheri WestMumbaiIndia

Objective:To compare the differences in adverse effects and efficacy profile between bacillus calmette-guerin(BCG)Danish 1331 and BCG Moscow-I strain in management of non-muscle invasive bladder ***:Clinical data of 188 cases of non-muscle invasive bladder cancer treated with BCG between January 2008 and December 2018 in our institute were collected prospectively and analysed retrospectively,and 114 patients who completed a minimum of 12 months of follow-up were *** and tumor characteristics,strain of BCG,adverse effects,and tumor progression were included for *** BCG was instilled in intermediate-and high-risk *** weeks of induction BCG,followed by three weekly maintenance BCG at 3,6,12,18,and 24 months was advised in high-risk ***:Overall 68 patients received BCG Danish 1331 strain and 46 patients received Moscow-I *** and tumor characteristics were well balanced between the two *** median follow-up period was 42.5 months and 34.5 months in Danish 1331 and Moscow-I groups,*** events like dropout rate,antitubercular treatment requirement,and need of cystectomy were higher in Moscow-I group(n=31,67.4%)when compared to Danish 1331 strain(n=33,48.5%)(p=0.046).On direct comparison between Danish 1331 and Moscow-I strain,there was similar 3-year recurrence-free survival(80.0%vs.72.9%)and 3-year progression-free survival(96.5%vs.97.8%).Conclusion:Study results suggest no significant differences between Danish 1331 and Moscow-I strain in recurrence-free survival and progression-free survival,but a significantly higher incidence of moderate to severe adverse events in BCG Moscow-I strain.

关键词： Adjuvant bacillus calmette-guerin bacillus calmette-guerin adverse effects Danish 1331 strain Intravesical therapy Moscow-I strain Non-muscle invasive bladder cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：