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The Current Acceptance,Accessibility and Recognition of Chinese and ayurvedic medicine in the United States in the Public,Governmental,and Industrial Sectors

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Chinese Journal of Integrative medicine 2012年第6期18卷 405-408页

作者： Jongbae J.PARK Selena Beckman-Harned Gayoung Cho Duckhee Kim Hangon Kim Asian medicine and Acupuncture Research Department of Physical Medicine and RehabilitationUniversity of North Carolina at Chapel HillChapel HillNCUSA Institute AMOREPACIFIC CorporationYongin-siGyeonggi-doKorea446-729

To assess the current level of acceptance in the United States of complementary and alternative medicine, recent research into the prevalence, acceptance, accessibility, and recognition of complementary and alternative therapies were reviewed. Several signs point to an increasing acceptance of complementary and alternative medicine in the United States; the use of complementary and alternative medicine is significantly increasing, many aspects of Chinese medicine and Ayurveda are becoming mainstream, practitioners in the United States are beginning to be licensed, and insurance companies are beginning to cover some complementary and alternative therapies. Remaining challenges to true acceptance include the restrictive Western mindset, the absence of published studies, a lack of consistent manufacturing processes and quality standards, and a fear of adulteration. Although the field still faces many challenges, alternative and complementarymedicine, including Chinese medicine and ayurvedic medicine, is becoming more accepted and accessible in the United States.

关键词： complementary therapies alternative medicine Chinese medicine ayurvedic medicine United States

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Protective Roles of Shilajit in Modulating Resistin,Adiponectin,and Cytokines in Rats with Non-alcoholic Fatty Liver Disease

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Chinese Journal of Integrative medicine 2022年第6期28卷 531-537页

作者： Baran Ghezelbash Nader Shahrokhi Mohammad Khaksari Gholamreza Asadikaram Maryam Shahrokhi Sara Shirazpour Physiology Research Center Kerman University of Medical SciencesKerman***Iran Endocrinology and Metabolism Research CenterKerman University of Medical SciencesKerman***Iran Department of Biochemistry School of MedicineKerman University of Medical SciencesKerman***Iran Department of Medical Science School of DentistryShiraz University of Medical SciencesShiraz713414336Iran Department of Physiology and Pharmacology Faculty of MedicineKerman University of Medical SciencesKerman***Iran

Objective:To evaluate the effect of Shilajit,a medicine of Ayurveda,on the serum changes in cytokines and adipokines caused by non-alcoholic fatty liver disease(NAFLD).Methods:After establishing fatty liver models by feeding a high-fat diet(HFD)for 12 weeks,35 Wistar male rats were randomly divided into5 groups,including control(standard diet),Veh(HFD+vehicle),high-dose Shilajit[H-Sh,HFD+250 mg/(kg·d)Shilajit],low-dose Shilajit[L-Sh,HFD+150 mg/(kg·d)Shilajit],and pioglitazone[HFD+10 mg/(kg·d)pioglitazone]groups,7 rats in each group.After 2-week of gavage administration,serum levels of glucose,insulin,interleukin1 beta(IL-1β),IL-6,IL-10,tumor necrosis factor-alpha(TNF-α),adiponectin,and resistin were measured,and insulin resistance index(HOMA-IR)was calculated.Results:After NAFLD induction,the serum level of IL-10 significantly increased and serum IL-1β,TNF-αlevels significantly decreased by injection of both doses of Shilajit and pioglitazone(P<0.05).Increases in serum glucose level and homeostasis model of HOMA-IR were reduced by L-Sh and H-Sh treatment in NAFLD rats(P<0.05).Both doses of Shilajit increased adiponectin and decreased serum resistin levels(P<0.05).Conclusion:The probable protective role of Shilajit in NAFLD model rats may be via modulating the serum levels of IL-1β,TNF-α,IL-10,adipokine and resistin,and reducing of HOMA-IR.

关键词： non-alcoholic fatty liver disease Shilajit adipokines cytokines glucose insulin dietary supplement ayurvedic medicine

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A Strategy to Employ Clitoria ternatea as a Prospective Brain Drug Confronting Monoamine Oxidase (MAO) Against Neurodegenerative Diseases and Depression

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Natural Products and Bioprospecting 2015年第6期5卷 293-306页

作者： A.Anita Margret T.Nargis Begum S.Parthasarathy S.Suvaithenamudhan Department of Biotechnology and Bioinformatics Bishop Heber CollegeTiruchirappalli 620017India Department of Biotechnology Jamal Mohamed CollegeTiruchirappalli 620020India Department of Bioinformatics School of Life SciencesBharathidasan UniversityTiruchirappalli 620024India

Ayurveda is a renowned traditional medicine practiced in India from ancient times and Clitoria ternatea is one such prospective medicinal herb incorporated as an essential constituent in a brain tonic called as medhya rasayan for treating neurological disorders.This work emphasises the significance of the plant as a brain drug there by upholding Indian medicine.The phytochemicals from the root extract were extricated using gas chromatography–mass spectrometry assay and molecular docking against the protein Monoamine oxidase was performed with four potential compounds along with four reference compounds of the plant.This persuades the prospect of C.ternatea as a remedy for neurodegenerative diseases and depression.The in silico assay enumerates that a major compound(Z)-9,17-octadecadienal obtained from the chromatogram with a elevated retention time of 32.99 furnished a minimum binding affinity energy value of-6.5 kcal/mol against monoamine oxidase(MAO-A).The interactions with the amino acid residues ALA 68,TYR 60 and TYR 69 were analogous to the reference compound kaempferol-3-monoglucoside with a least score of-13.90/-12.95 kcal/mol against the isoforms(MAO)A and B.This study fortifies the phytocompounds of C.ternatea as MAO-inhibitors and to acquire a pharmaceutical approach in rejuvenating ayurvedic medicine.

关键词： (Z)-9,17-Octadecadienal Kaempferol-3-monoglucoside Monoamine oxidase Clitoria ternatea Molecular docking ayurvedic medicine

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Medicinal values of aquatic plant genus Nymphoides grown in Asia: A review

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Asian Pacific Journal of Tropical Biomedicine 2018年第2期8卷 113-119页

作者： Zihan Rahman Khan Nargis Sultana Chowdhury Suriya Sharmin Md.Hossain Sohrab Pharmaceutical Sciences Research Division BCSIR Laboratories Department of Pharmacy Manarat International University

Nymphoides is an aquatic genus consisting about 50 species, of which few were accepted as traditional medicinal plants in Asia. The literature review revealed that Nymphoides species are widely used in ayurvedic medicine as a popular drug, i.e. Tagara. They are also utilized by the traditional local healers of different Asian countries to treat various diseases, like convulsion, jaundice, fever, headache, etc. According to the in vivo and in vitro pharmacological studies, Nymphoides species have been claimed to possess major biological activities like anticonvulsant, antioxidant, hepatoprotective, cytotoxic, antitumor, etc. Biochemical profiling of different aquatic plants of this genus revealed the presence of some important phytochemicals as polyphenolic component, flavonoids, triterpenes, carbohydrates, glycosides, etc. Several valuable bioactive compounds including ephedrine, coumarin, secoiridoid glucosides, methyl quercetin, ferulic acid, foliamenthoic acid, etc. were also known to be isolated and identified from different Nymphoides species. The aim of this review is to analyze the published report based on the medicinal values of different Asian Nymphoides species, to provide the updated information about the ethnomedicinal, pharmacological as well as the phytochemical properties for the first time.

关键词： Nymphoides Aquatic ayurvedic medicine Phytochemicals

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