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The Role of atherosclerosis and inflammation in the Development of Descending Aortic Aneurysms: Special Aspects of Medical Correction

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Health 2016年第13期8卷 1335-1348页

作者： Vladimir Petrovich Krylov Nikolay Andreevich Mana Leonid Petrovich Titov Valentina Nikolaevna Gayduk Leonid Ivanovich Reut Nadezhda Vladimirovna Mankevich Alexander Stanislavovich Zhigalcovitch Aleksey Leonidovich Smolyakou Gennady Adolfovich Popel Roman Nikolaevich Pyzhyk Republican Scientific and Practical Centre “Cardiology” Ministry of Health of Belarus Minsk Belarus Republican Scientific and Practical Centre “Epidemiology and Microbiology” Ministry of Health of Belarus Minsk Belarus Belarusian Medical Academy of Post-Graduate Education Minsk Belarus

Modern medicine has achieved much progress in the field of medical and surgical repair of a variety of disorders. It is especially true for the early stages of treatments. In long-term period, however, instead of recovery, we frequently observe progressive regression, which completely annuls all our efforts. Moreover, the algorithm used to correct acute process may sometimes be detrimental to organs and tissues. Such situation is also frequent in the treatment of atherosclerotic descending aortic aneurysms (DAA). This is because the successful medical and even surgical repair to prevent aneurysm rupture in long-term period may trigger some detrimental processes in other regions thus producing negative results of the treatment. The present article doesn’t aim to prove some provisions in DAA clinical picture, atherosclerosis and inflammatory states. But we have faced some systematicity at these clinical implications which are absolutely not specified in literature. We have managed to find an explanation for this thing making a scrupulous analysis of nonsurgical sources. Comparing them with our observations, we have found out that aseptic and septic inflammation of connective tissue, probably, is a key component in the formation of DAA disregarding of which correction of dyslipidemia may lead to negative results. We are looking for in-depth research and discussion.

关键词： Aneurism Formation atherosclerosis and inflammation Aortic Aneurisms

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