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Feasibility of Tiotropium Bromide Treatment in Patients with asthma-copd overlap syndrome and its Effect on Lung Function

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Journal of Clinical and Nursing Research 2023年第4期7卷 100-104页

作者： Li Sheng Hohhot First Hospital Hohhot 010030Inner MongoliaChina

Objective:To explore the feasibility of tiotropium bromide therapy and its effect on the lung function of patients with asthma-copd overlap syndrome(ACOS).Method:The 58 subjects selected in this study were all ACOS patients admitted to our hospital(Hohhot First Hospital)from October 2020 to October *** were grouped according to the random number table method and divided into a control group(29 cases)and an observation group(29 cases).The control group received routine treatment plus salmeterol-fluticasone powder inhalation treatment,and the observation group received tiotropium bromide *** relevant indicators of the two groups were ***:The total clinical effective rate of the observation group was significantly higher than that of the control ***,the forced vital capacity(FVC),forced expiratory volume in 1 second(FEV1)levels,and ACT scores of the two groups increased after treatment,with the observation group having better results than the control *** residual volume-total lung capacity ratio(RV/TLC),acute exacerbation frequency,and CAT scores all decreased,with the observation group showing smaller values than the control *** difference between the results of both groups were significant(P<0.05)Conclusion:Tiotropium bromide has a significant clinical effect in the treatment of ACOS patients and can effectively improve the lung function of patients.

关键词： asthma-copd overlap syndrome Tiotropium bromide Lung function Feasibility

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