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Biological removal of antiandrogenic activity in gray wastewater and coking wastewater by membrane reactor process

Journal of Environmental Sciences 2015年第7期27卷 195-202页

作者： Dehua Ma Lujun Chen Cong Liu Chenjun Bao Rui Liu School of Environment Tsinghua University Zhejiang Provincial Key Laboratory of Water Science and Technology

A recombinant human androgen receptor yeast assay was applied to investigate the occurrence of antiandrogens as well as the mechanism for their removal during gray wastewater and coking wastewater treatment. The membrane reactor（MBR） system for gray wastewater treatment could remove 88.0% of antiandrogenic activity exerted by weakly polar extracts and 97.3% of that by moderately strong polar extracts, but only 32.5%of that contributed by strong polar extracts. Biodegradation by microorganisms in the MBR contributed to 95.9% of the total removal. After the treatment, the concentration of antiandrogenic activity in the effluent was still 1.05 μg flutamide equivalence（FEQ）/L, 36.2%of which was due to strong polar extracts. In the anaerobic reactor, anoxic reactor, and membrane reactor system for coking wastewater treatment, the antiandrogenic activity of raw coking wastewater was 78.6 mg FEQ/L, and the effluent of the treatment system had only 0.34 mg FEQ/L. The antiandrogenic activity mainly existed in the medium strong polar and strong polar extracts. Biodegradation by microorganisms contributed to at least 89.2%of the total antiandrogenic activity removal in the system. Biodegradation was the main removal mechanism of antiandrogenic activity in both the wastewater treatment systems.

关键词： Biological removal antiandrogenic activity Gray wastewater Coking wastewater Membrane reactor

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ANDROGEN RECEPTOR ACTIVITIES OF P,P’ -DDE, FENVALERATE AND PHOXIM DETECTED BY ANDROGEN RECEPTOR REPORTER GENE ASSAY

ANDROGEN RECEPTOR ACTIVITIES OF P,P’ -DDE, FENVALERATE AND ...

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海峡两岸第三届毒理学研讨会

作者：徐莉春王心如 Institute of Toxicology Nanjing Medical University Institute of Toxicology Nanjing Medical University

＜正＞In this study, we have developed a transient human androgen receptor （hAR） reporter gene assay using African monkey kidney cell line CV-1. The assay displayed appropriate response to the known AR agonist 5α-dihydrotestosterone （DHT） and AR antagonist nilutamide. DHT induced AR-mediated transcriptional activity in a concentration-dependent manner with median

关键词： Reporter gene assay Human androgen receptor African monkey kidney cell antiandrogenic activity Pesticide

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