检索结果-南通市图书馆

软件和集成电路 1999年第1期 87-87页

作者：任永杰

Panda EnterpriSecure antivirus：多重防护

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网管员世界 2004年第6期 33-33页

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备份诺顿antivirus病毒库

玩电脑（在线技术） 2005年第10期 83-83页

作者：独行

诺顿的Live Update在线升级以后，打开系统盘的“／***／common files／symantec shared／virusdefs”目录，在里面有几个以时间命名的文件夹，备份其中最新的一个文件夹。

关键词： antivirus 备份病毒库 Update Live 在线升级文件夹系统盘目录

缉毒勇士[Norton antivirus 2003中文版]

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个人电脑 2003年第4期9卷 64-64页

作者：郑昊

Symantec公司的Norton antivirus（NAV）一直有着良好的口碑，它非常直观、易于上手NAV 2003会自动连接Internet更新软件和病毒定义。<（共1页)

关键词：赛门铁克公司杀毒软件 Norton antivirus 2003中文版病毒防护功能 NAV隔离区防毒效果

Synthesis and antiviral activity of 4H-[1,2,5]oxadiazolo-[3,4-d]pyrimidine-5,7-dione 1-oxide nucleosides

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Chinese Chemical Letters 2009年第4期20卷 404-406页

作者： Jing Bo Shi Jing Gao Ya Ping Wang Qi Zheng Yao School of Pharmacy China Pharmaceutical University Nanjing 210009 China School of Pharmacy Anhui Medical University Hefei 230032 China School of Pharmaceutical Science Jiangsu University Zhenjiang 212013 China Zhaoke Pharmaceutical Company Limited Hefei 230088 China

A series of 4H-[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-dione 1-oxide nucleosides was designed, synthesized and evaluated against vesicular stomatitis virus （VSV） in Wish cell. The antiviral activities of all compound... 详细信息

关键词： Oxadiazolo[3,4-d]pyrimidine nucleoside antivirus Synthesis

Virus-Encoded microRNAs: Future Therapeutic Targets?

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Cellular & Molecular Immunology 2006年第6期3卷 411-419页

作者： Peng Qi Jinxiang Han Yanqin Lu Chuanxi Wang Fanfeng Bu Shandong Medicinal Biotechnology Center Shandong Academy of Medical Science Key laboratory of Ministry of Health for Biotech-Drug Jinan 250062 China School of Medicine Shandong University Jinan 250012 China

The discovery of microRNAs （miRNAs） is a remarkable breakthrough in the field of molecular genetics, as miRNAs are key actors which regulate gene expression in diverse cellular processes from unicellular yeast to human. The recent discovery of virus-encoded miRNAs indicates that viruses also use this fundamental mode of gene regulation. Research into viral miRNAs function demonstrates that some miRNAs play an important role in regulating both the viral life cycle and the interaction between viruses and their hosts. The first in vivo ＂antagomir＂ study provides an exciting first step towards miRNA therapy, and the potential for ultimately designing molecular medicines based on the modulation of miRNAs seems good.

关键词： microRNA gene expression anti-miRNA oligonucleotide therapeutic target antivirus

Review on supermolecules as chemical drugs

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Science China Chemistry 2009年第4期52卷 415-458页

作者： ZHOU ChengHe GAN LinLing ZHANG YiYi ZHANG FeiFei WANG GuangZhou JIN Lei GENG RongXia School of Chemistry and Chemical Engineering Southwest UniversityChongqing 400715China School of Pharmaceutical Sciences Southwest UniversityChongqing 400715China

Supramolecular medicinal chemistry field has been a quite rapidly developing,increasingly active and newly rising interdiscipline which is the new expansion of supramolecular chemistry in pharmaceu-tical sciences,and is gradually becoming a relatively independent scientific area. Supramolecular drugs could be defined as medicinal supermolecules formed by two or more molecules through non-covalent bonds. So far a lot of supermolecules as chemical drugs have been widely used in clinics. Supermolecules as chemical drugs,i.e. supramolecular chemical drugs or supramolecular drugs,which might have the excellences of lower cost,shorter period,higher potential as clinical drugs for their successful research and development,may possess higher bioavailability,better biocompatibility and drug-targeting,fewer multidrug-resistances,lower toxicity,less adverse effect,and better curative effects as well as safety,and therefore exhibit wide potential application. These overwhelming advan-tages have drawn enormous special attention. This paper gives the definition of supramolecular drugs,proposes the concept of supramolecular chemical drugs,and systematically reviews the recent ad-vances in the research and development of supermolecules,including organic and inorganic complex ones as chemical drugs in the area of antitumor,anti-inflammatory,analgesic,antimalarial,antibacterial,antifungal,antivirus,anti-epileptic,cardiovascular agents and magnetic resonance imaging agents and so on. The perspectives of the foreseeable future and potential application of supramolecules as chemical drugs are also presented.

关键词： supramolecular chemistry cyclodextrin porphyrin complex anticancer anti-inflammatory antibacterial antifungal antivirus cardiovascular agent magnetic resonance imaging agent supramolecular drug

Potential Treatment of COVID-19 with Traditional Chinese Medicine: What Herbs Can Help Win the Battle with SARS-CoV-2?

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Engineering 2022年第12期19卷 139-152页

作者： Lin Li Yuzheng Wu Jiabao Wang Huimin Yan Jia Lu Yu Wang Boli Zhang Junhua Zhang Jian Yang Xiaoying Wang Min Zhang Yue Li Lin Miao Han Zhang State Key Laboratory of Component-Based Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae Ministry of EducationTianjin University of Traditional Chinese MedicineTianjin 301617China Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Laboratory of Pharmacology of TCM Formulae Co-Constructed by the Province–Ministry Tianjin University of Traditional Chinese MedicineTianjin 301617China School of Integrative Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Evidence-Based Medicine Center Tianjin University of Traditional Chinese MedicineTianjin 301617China College of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China

Traditional Chinese medicine(TCM)has been successfully applied worldwide in the treatment of coronavirus disease 2019(COVID-19),which is caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).However,the pharmacological mechanisms underlying this success remain ***,the aim of this review is to combine pharmacological assays based on the theory of TCM in order to elucidate the potential signaling pathways,targets,active compounds,and formulas of herbs that are involved in the TCM treatment of COVID-19,which exhibits combatting viral infections,immune regulation,and amelioration of lung injury and *** reports on target screening are elucidated using virtual prediction via docking analysis or network pharmacology based on existing *** results of these reports indicate that an intricate regulatory mechanism is involved in the pathogenesis of ***,more pharmacological research on the natural herbs used in TCM should be conducted in order to determine the association between TCM and COVID-19 and account for the observed therapeutic effects of TCM against COVID-19.

关键词： Traditional Chinese medicine SARS-CoV-2 COVID-19 antivirus Anti-inflammation Immune regulation

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反病毒软件防护EANSS模型的设计与实现

哈尔滨理工大学学报 2017年第6期22卷 72-75页

作者：刘鑫宋显华吴世鹏李增光张欢王凯哈尔滨理工大学现代教育技术中心黑龙江哈尔滨150080 哈尔滨理工大学应用科学学院黑龙江哈尔滨150080

针对ANSS(antivirus software shield)模型的不足,扩展了ANSS模型提出了EANSS(enhanced antivirus software shield)模型,将新的攻击规则融入到新的模型中,并且在EANSS模型中加入了实时监控机制、自学习机制来提高保护的能力。实验结果... 详细信息

针对ANSS(antivirus software shield)模型的不足,扩展了ANSS模型提出了EANSS(enhanced antivirus software shield)模型,将新的攻击规则融入到新的模型中,并且在EANSS模型中加入了实时监控机制、自学习机制来提高保护的能力。实验结果表明:EANSS模型不影响系统的正常运行,可以对反病毒软件进行更好的保护,同时占用较低的系统内存和CPU占用率。

关键词：杀毒软件 antivirus Software Shield模型恶意软件 Application Programming

Synthesis of new pyrimidine nucleoside derivatives with nitric oxide donors for antiviral activity

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Chinese Chemical Letters 2011年第8期22卷 899-902页

作者： Jing Bo Shi Song Xu Ya Ping Wang Jing Jing Li Qi Zheng Yao School of Pharmacy China Pharmaceutical University Naniing 210009 China School of Pharmacy Anhui Medical University Hefei 230032 China Anhui Zhaoke Pharmaceutical Co. Ltd. Hefei 230088 China

New pyrimidine nucleoside derivatives with nitric oxide（NO） donor were systematically *** antivirus activities of these nucleoside analogues against vesicular stomatitis virus（VSV） in Wish cell were *** was demonstrated that most of compounds had stronger antiviral acitivity than acyclovir,while their toxicities were similar or lower to acyclovir.

关键词： Pyrimidine nucleoside NO-donor antivirus Furoxans Oximes Synthesis