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Changing common sense:anti-platelet/coagulation therapy against cirrhosis

World Journal of Hepatology 2015年第13期7卷 1730-1734页

作者： Yoshihiro Ikura Tatsuya Osuga Department of Pathology Takatsuki General Hospital Department of Gastroenterology Takatsuki General Hospital

Until recently,anti-platelet/coagulation therapy had not been recommended for patients with *** venous thrombosis is one of the representative complications of cirrhosis and ischemic disorders associated with atherosclerosis are not infrequent in cirrhotic patients,many clinicians have tended to hesitate to introduce anti-platelet/coagulation therapy to their ***,this is due to the increased risk of hemorrhagic diathesis in cirrhotic ***,accumulating evidence has revealed the benefits of anti-platelet/coagulation therapy for cirrhotic *** addition to the safety of the therapy carried out against cardiovascular diseases in cirrhotic patients,some clinical data have indicated its preventive effect on venous ***,the efficacy of antiplatelet/coagulation therapy against cirrhosis itself has been demonstrated both clinically and *** conceptual basis for application of anti-platelet/coagulation therapy against cirrhosis was constructed through two pathologic studies on intrahepatic thrombosis in cirrhotic *** may be better to use thrombopoietinreceptor agonists,which have been tested as a treatment for cirrhosis-related thrombocytopenia,in combination with anti-platelet drugs to reduce the risk of venous *** the last decade,the World Journal of Gastroenterology,a sister journal of World Journal of Hepatology,has been one of the main platforms of active discussion of this theme.

关键词： anti-platelet/coagulation therapy Cirrhosis Hemorrhagic diathesis Thrombosis Thrombocytopenia

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