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Observation of peripheral refraction in myopic anisometropia in young adults

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 2082-2088页

作者： Yu-Qin Du Yue-Hua Zhou Ming-Wei Ding Ming-Xu Zhang Yu-Juan Guo Shan-Shan Ge Eye School of Chengdu University of TCM Ineye Hospital of Chengdu University of TCMChengdu 610036Sichuan ProvinceChina Beijing Ming Vision and Ophthalmology Beijing 100010China

AIM:To investigate the differences in retinal refraction difference values(RDVs)of adult patients with myopic anisometropia compared with those without myopic anisometropia,and to investigate the relationship between ocular biometric measurements and relative peripheral ***:This clinical observation study included 130 patients with myopia(-0.25 to-10.00 D)between October 2022 and January 2023 aged between 18 and *** patients were divided into anisometropia(n=63;difference in binocular anisometropia≥1.00 D)and non-anisometropia(n=67;difference in binocular anisometropiaanisometropia group,the TRDV,RDV-20-53,RDV-superior,and more myopic eyes had significantly higher RDVtemporal values than less myopic eyes.(Panisometropia group,there was no significant difference in the RDV between the more and less myopic eyes at different eccentricities(P>0.05).There was a negative correlation between SE and TRDV(r=-0.205,P=0.001),RDV-20-53(r=-0.281,-0.183,-0.176,P<0.05),RDV-superior(r=-0.251,P<0.001),and RDV-temporal(r=-0.230,P<0.001),a negative correlation between CYL and RDV-10-30(r=-0.147,-0.180

关键词： myopia anisometropia peripheral refraction multispectral refractive topography axial length

Effectiveness and the nomogram of small incision lenticule extraction in the correction of myopic anisometropia in adults

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International Journal of Ophthalmology(English edition) 2023年第11期16卷 1838-1844页

作者： Tong Zhang Lu Zhu Hang-Jia Zuo Zhi-Jun Chen Yan Ji Xin Yang Xiao-Rong Lu Qiong Wu Qing Wang Jiu-Yi Xia Meng Li Chun-Jiang Zhou Yao Wang Ke Hu Wen-Juan Wan Nomogram of SMILE surgery for adult anisometropia 1Chongqing Medical University Chongqing 400000China The First Affiliated Hospital of Chongqing Medical University Chongqing Key Laboratory of OphthalmologyChongqing Eye InstituteChongqing Branch(Municipality Division)of National Clinical Research Center for Ocular DiseasesChongqing 400000China

AIM:To evaluate the safety,effectiveness,and predictability of small incision lenticule extraction(SMILE)for the treatment of anisometropia,and to explore the personalized design scheme of SMILE in correcting adult myopia anisometropia based on the ***:It’s a prospective cohort *** with anisometropic myopia of refractive difference≥2.0 diopters(D)who underwent SMILE between September 2020 and March 2021 were *** features and visual function were assessed preoperatively and at 1wk,1,3,and 6mo after the *** examination included tests for uncorrected distance visual acuity(UDVA),corrected distance visual acuity(CDVA),refractive errors,effectiveness index(preoperative CDVA/postoperative UDVA),safety index(postoperative CDVA/preoperative CDVA),nomogram and stereoscopic *** t-test,Wilcoxon signed-rank test and repeated-measures analyses of variance were used for continuous variables,and Pearson Chi-squared test was used for categorical ***:The study involved 45 consecutive patients(average age:25.0±6.9y;82 out of 90 eyes underwent SMILE,while 8 eyes were not operated).The average preoperative spherical equivalent(SE)was-4.74±0.22 *** months after surgery,the effectiveness index was 1.05±0.12,and the safety index was 1.09±*** eyes(85.4%)exhibited SE correction error within±0.5 *** percentage of eyes with Titmus stereoscopic function equal to or less than 200”significantly increased from 55.6%preoperatively to 88.9%postoperatively(Panisometropia,and it improves stereoscopic visual function of anisometropia *** precise and individualized design of the nomogram is a vital element to ensure the balance of both eyes after SMILE.

关键词： refractive surgery small incision lenticule extraction anisometropia nomogram

Noninvasive stiffness assessment of the human lens nucleus in patients with anisometropia using an ultrasound elastography system

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International Journal of Ophthalmology(English edition) 2020年第3期13卷 399-405页

作者： Hai-Yan Zhou Hong Yan Wei-Jia Yan Xin-Chuan Wang Qiao-Ying Li Department of Ophthalmology Shaanxi Provincial People’s HospitalThird Affiliated Hospital of the School of MedicineXi’an Jiaotong UniversityXi’an 710038Shaanxi ProvinceChina Xi’an Fourth Hospital Shaanxi Eye HospitalAffiliated Xi’an Fourth HospitalNorthwestern Polytechnical UniversityXi’an 710004Shaanxi ProvinceChina Medical School the University of SheffieldWestern BankSheffieldS102TNUK Basic Medical School Air Force Medical UniversityXi’an 710068Shaanxi ProvinceChina Department of UItrasonic Diagnosis Tangdu HospitalAir Force Medical UniversityXi’an 710038Shaanxi ProvinceChina

AIM:To investigate the significance of ultrasound elastography for evaluating stiffness of the human lens nucleus in patients with ***:A total of 14 patients(28 eyes)with anisometropia were *** difference in refractive status between two eyes≥-4.0 diopters(D)and the difference in axial length(AL)of the eyes was≥3 *** were 5 males and 9 females with an average age of 62±3.3 *** test data of the long AL eye of each patient was included in group A(14 eyes),and test data of the eye with relative short AL was included in group *** nuclear stiffness was measured with free-hand qualitative elastography by independent *** gray scale and color-coded elastography maps were *** each case,three consecutive measurements were performed and strain ratio was used for statistical *** and sectional view of the lens were analyzed and archived by anterior segment ***:In the long AL group,the strain rate in the nucleus of the lens was 0.16%±0.08%;in the short AL group,the strain rate in the nucleus of the lens was 0.54%±0.16%.Independent sample t-test analyses showed that the long AL group lens had a significantly smaller nuclear strain rate than the relatively short AL group,P<***:The relationship between human lens stiffness and different AL is demonstrated by ultrasound *** long AL is associated with lower strain ratio and less resilience of the lens.

关键词： ultrasound elastography human lensnucleus stiffness anisometropia

Assessment of the effects of induced anisometropia on binocularity with glasses-free 3D technique

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International Journal of Ophthalmology(English edition) 2023年第4期16卷 601-607页

作者： Xu-Bo Yang Wei-Dong Huang Yong-Chuan Liao Department of Ophthalmology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Optometry and Visual Science West China School of MedicineSichuan UniversityChengdu 610041Sichuan ProvinceChina

AIM:To assess the effect of experimentally induced anisometropia on binocularity in normal adults with glassesfree three-dimensional(3D)***:Totally 54 healthy medical students with normal binocularity in the cross-sectional study were *** was induced by placing trail lenses over the right eye,in 0.5 D steps including lenses of-0.5,-1,-1.5,-2,-2.5 D(hyperopic anisometropia)and lenses of+0.5,+1,+1.5,+2,+2.5 D(myopic anisometropia).The glasses-free 3D technique was used to evaluated not only fine stereopsis,but also coarse stereopsis,dynamic stereopsis,foveal suppression,and peripheral suppression in these ***-way analysis of variance was used to compare quantitative data such as fine stereopsis,coarse ***’s Chi-square test was performed to compare categorical data such as dynamic stereopsis,foveal suppression and peripheral ***:The subjects showed a statistically significant decline in fine stereopsis,coarse stereopsis,and dynamic stereopsis with increasing levels of anisometropia(Panisometropia was more than 1 D(Panisometropia(Panisometropia may have a potentially significant effect on high-grade binocular *** mechanisms underlying the defect of binocularity seem to involve not only foveal suppression,but also peripheral suppression.

关键词： anisometropia binocularity stereopsis glasses-free 3D technique

Relative peripheral refractive errors in Chinese children with myopic anisometropia

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International Journal of Ophthalmology(English edition) 2024年第11期17卷 2074-2081页

作者： Yu-Ting Tong Yu-Qin Du Shan-Shan Ge Li Chen Xiao-Qi Ma Yu-Juan Guo Yue-Hua Zhou Eye School of Chengdu University of Traditional Chinese Medicine(TCM) Chengdu 610036Sichuan ProvinceChina Ineye Hospital of Chengdu University of TCM Chengdu 610036Sichuan ProvinceChina Key Laboratory of Sichuan Province Ophthalmopathy Prevention&Cure and Visual Function Protection with TCM Laboratory Chengdu 610036Sichuan ProvinceChina Beijing Ming Vision and Ophthalmology Beijing 100010China

AIM:To compare relative peripheral refractive errors(RPREs)in Chinese children with and without myopic anisometropia(MAI)and to explore the relationship between RPRE and ***:This observational cross-sectional study included 160 children divided into two groups according to the interocular spherical equivalent refraction(SER)difference≥1.0 D in the MAI group(n=80)and<1.0 D in the non-MAI group(n=80).The MAI group was further divided into two subgroups:ΔSER<2.0 D group and ΔSER≥2.0 D *** ocular biometric parameters of axial length(AL),average keratometry(Ave K),cylinder(CYL),surface regularity index(SRI),and surface asymmetry index(SAI)were *** addition,multispectral refraction topography was performed to measure RPRE,and the parameters were recorded as total refraction difference value(TRDV),refraction difference value(RDV)0-10,RDV10-20,RDV20-30,RDV30-40,RDV40-53,RDV-superior(RDV-S),RDV-inferior(RDV-I),RDV-temporal(RDV-T)and RDV-nasal(RDV-N).RESULTS:In the non-MAI group,the interocular differences of all parameters of RPRE were not *** the MAI group,the interocular differences of TRDV,RDV10-53,RDV-S,RDV-I,RDV-T,and RDV-N were *** subgroup analysis,the interocular differences of TRDV,RDV30-53,RDV-I,and RDV-T were significant in ΔSER<2.0 D group and ΔSER≥2.0 D group,but the interocular differences of RDV10-30,RDV-S and RDV-N were only significant in the ΔSER≥2.0 D *** correlation analysis,ΔTRDV,ΔRDV 10-53,ΔRDV-S,and ΔRDV-N were negatively correlated with ΔSER but positively correlated with Δ***:The more myopic eyes have larger hyperopic RPRE in Chinese children with MAI in certain retinal range,and partialΔRPRE is closely associated with ΔSER and ΔAL.

关键词： myopia anisometropia relative peripheral refractive error ocular biometric parameters

Association between anisometropia as Well as Visual Acuity, Aniseikonia, and Stereopsis in the Absence of Strabismus

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Open Journal of Ophthalmology 2022年第2期12卷 129-141页

作者： David Tayah Marcelo Tannous Youssef Sabba Tayah Milton Ruiz Alves Universidade de Sã o Paulo S&#227 o Paulo Brazil Universidade Federal do Amazonas Manaus Brazil Universidade Nilton Lins Manaus Amazonas Brazil

Objective: The current study aimed to assess the association between the type of anisometropia and its effects on monocular and binocular best-corrected vision acuity (BCVA), aniseikonia, and stereopsis in the absence of strabismus. Methods: In total, 162 individuals with anisometropia and healthy eyes and without a previous history of amblyopia therapy and eye surgery were included in the analysis. According to spherical and cylindrical components and spherical equivalent, they were divided into the spherical hyperopic anisometropia (SHA, n = 31), spherical myopic anisometropia (SMA, n = 45), astigmatic or cylindrical hyperopic anisometropia (CHA, n = 22), and astigmatic or cylindrical myopic anisometropia (CMA, n = 64) groups. Patients without anisometropia (NA, n = 188) were classified under the control group. The effects of anisometropia on monocular and binocular BCVA, aniseikonia, and stereoacuity were examined. Results: The NA group had a significantly lower LogMAR of BCVA of the right eye (RE), left eye (LE), worse eye than the SHA, SMA, CMA, and CHA groups. Moreover, the SMA group had significantly lower LogMAR of BCVA than the CHA group (p Conclusion: Worse visual levels of the RE, LE, worse eye, BCVA difference, and lower stereopsis were evidenced in each type of anisometropia defined in this study. Cylindrical hyperopic anisometropia (CHA) resulted in a statically significant worsening VA level and stereopsis than cylindrical myopic (CMA) or spherical myopic anisometropia.

关键词： anisometropia Visual Acuity Aniseiconia Stereoacuity Depth Perception

Stereopsis, Aniseikonia, and Associated Symptoms in Patients with Bilateral Pseudophakia with and without anisometropia: A Comparative Study

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Open Journal of Ophthalmology 2022年第1期12卷 107-120页

作者： Marcelo Tannous Daniel Dantas Paulo Roberto de Arruda Zantut David Tayah Pedro Carricondo Amaryllis Avakian Milton Ruiz Alves Departament of Ophthalmology and Otolaryngology of HOSPITAL das Clinicas from University of Sã o Paulo Medical School Sao Paulo Brazil Department of Computer Federal University of Sergipe Aracaju Brazil

Objectives: The study aimed to compare stereopsis, aniseikonia, and associated symptoms in bilateral pseudophakia with and without anisometropia. Methods: Patients with senile cataracts, previously scheduled for phacoemulsification with an IOL implant in both eyes were included in this cross-sectional study. Patients were divided into two groups: control group (n = 69) with an interocular post-surgical refraction difference in Spherical Equivalent (SE) ?;Stereotest. Ten symptoms related to aniseikonia were evaluated with a questionnaire. Statistical evaluation of data included models of univariate, multivariate, and regression analyses. Results: Cataract surgery-induced aniseikonia was 0.64% ± 1.41% in control group and 0.62% ± 1.76% in anisometropia group with an insignificant difference (p = 0.766). Measured stereoacuity was 1.95 ± 0.17 log10 seconds of arc in the control group and 2.12 ± 0.22 log10 seconds of arc in the anisometropia group with a significant difference (p Conclusions: The study showed that stereopsis, aniseikonia, and associated symptoms did not stand for a substantial problem for visual comfort of bilateral pseu- dophakia with anisometropia less than 3D.

关键词： Cataract Phacoemulsification Pseudophakia Aniseikonia Depth Perception anisometropia

Structural and functional alterations in the brains of patients with anisometropic and strabismic amblyopia:a systematic review of magnetic resonance imaging studies

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Neural Regeneration Research 2023年第11期18卷 2348-2356页

作者： Yuxia Wang Ye Wu Lekai Luo Fei Li Huaxi MR Research Center(HMRRC) Department of RadiologyWest China Hospital of Sichuan UniversityChengduSichuan ProvinceChina Department of Ophthalmology Laboratory of Optometry and Vision SciencesWest China Hospital/West China School of MedicineSichuan UniversityChengduSichuan ProvinceChina Department of Radiology West China Second Hospital of Sichuan UniversityChengduSichuan ProvinceChina

Amblyopia is the most common cause of vision loss in children and can persist into adulthood in the absence of effective *** clinical and neuroimaging studies have suggested that the neural mechanisms underlying strabismic amblyopia and anisometropic amblyopia may be ***,we performed a systematic review of magnetic resonance imaging studies investigating brain alterations in patients with these two subtypes of amblyopia;this study is registered with PROSPERO(registration ID:CRD42022349191).We searched three online databases(PubMed,EMBASE,and Web of Science) from inception to April 1,2022;39 studies with 633 patients(324patients with anisometropic amblyo pia and 309 patients with strabismic amblyopia) and 580 healthy controls met the inclusion criteria(e.g.,case-control designed,pee r-reviewed articles) and were included in this *** studies highlighted that both strabismic amblyopia and anisometropic amblyopia patients showed reduced activation and distorted topological cortical activated maps in the striate and extrastriate co rtices during tas k-based functional magnetic resonance imaging with spatial-frequency stimulus and retinotopic representations,respectively;these may have arisen from abnormal visual *** for amblyopia that are reflected in enhanced spontaneous brain function have been reported in the early visual cortices in the resting state,as well as reduced functional connectivity in the dorsal pathway and structural connections in the ventral pathway in both anisometro pic amblyopia and strabismic amblyopia *** shared dysfunction of anisometro pic amblyopia and strabismic amblyopia patients,relative to controls,is also chara cterized by reduced spontaneous brain activity in the oculomotor co rtex,mainly involving the frontal and parietal eye fields and the cerebellu m;this may underlie the neural mechanisms of fixation instability and anomalous saccades in *** regards to

关键词： amblyopia anisometropia brain function magnetic resonance imaging oculomotor system precortical pathway strabismus structure visual cortex

Factors influencing stereoacuity levels after surgery to correct unilateral developmental cataracts in children

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International Journal of Ophthalmology(English edition) 2013年第3期6卷 331-336页

作者： Soo Jung Lee Wan-Soo Kim Department of Ophthalmology Haeundae Paik Hospital

·AIM: To evaluate factors influencing stereoacuity after surgery to correct unilateral developmental pediatric cataracts. ·METHODS: We retrospectively surveyed 110 patients who had undergone removal of unilateral acquired developmental cataracts and primary posterior chamber intraocular lens implantation between February 1992 and December 2009. In all patients, stereoacuity was assessed using the Titmus test at the last follow -up period of minimum 2 years after surgery. Patients were divided into two groups according to the extent of stereoacuity : group 1 ( = 42 ) had stereoacuity values ≤ 100sec/arc and group 2 ( =68) values >100sec/arc. The values of ten parameters associated with stereoacuity were measured in each group: Cataract types, preoperative best corrected visual acuity (BCVA) of the affected eyes, preoperative inter -ocular difference of BCVA, age at cataract surgery, operative method, secondary cataract, postoperative strabismus, postoperative BCVA of the affected eyes, postoperative inter-ocular difference of BCVA, and anisometropia. ·RESULTS: The extent of stereoacuity was significantly associated with both operative method and secondary cataract ( =0.000 and =0.016, respectively). All patients in whom the posterior capsule was preserved, had poor stereoacuity >100sec/arc. Significant correlations with the extent of stereoacuity were found with postoperative strabismus ( =0.048),postoperative BCVA of the affected eyes ( =0.002), anisometropia ( =0.034). ·CONCLUSION: Postoperative stereoacuity was better in patients who underwent either optic capture or anterior vitrectomy after posterior continuous curvilinear capsulorhexis, and who didn’t develop secondary cataracts or strabismus postoperatively. Furthermore, postoperative BCVA of the affected eyes, and anisometropia influenced the stereoacuity of the patients surgically treated for unilateral developmental pediatric cataracts. ·

关键词： anisometropia developmental cataract secondary cataract stereoacuity stereopsis strabismus unilateral pediatric cataract visual acuity