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Prevalence of Primary Open angle glaucoma among Patients with Diagnosis of Systemic Hypertension and Diabetes Mellitus: The Colombian glaucoma Study

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Open Journal of Ophthalmology 2020年第2期10卷 99-114页

作者： Carlos E. Rivera Erika Cantor Andres Castillo Alexander Martinez Lyle Newball Juan C. Rueda Alejandro Valencia Sandra Belalcazar Tulio Cabal Oscar Albis-Donado Fabian Mendez Fundación Oftalmológica del Valle Cali Colombia Institute of Statistics Universidad de Valparaiso Valparaiso Chile Department of Biology Faculty of Natural & Exact Sciences Universidad del Valle Cali Colombia Ophthalmology Residency Program Universidad del Valle Centro Médico Imbanaco Cali Colombia Clínica Lynd Newball San Andrés Islas Colombia FOSCAL Internacional Bucaramanga Colombia glaucoma Unit Medellin Colombia Fundación Oftalmológica Nacional Bogotá Colombia Clínica Visión Cabal Buga Colombia Visual Sense Private Practice Mexico City Mexico School of Public Health GESP Group Universidad del Valle Cali Colombia

Objective: To establish the prevalence and risk factors of Primary Open angle glaucoma (POAG) among patients with Systemic Hypertension (SH) and Diabetes Mellitus (DM) in six cities of Colombia. Methods: A cross-sectional study among hypertensive and diabetic patients was conducted in Colombia. This study included 2067 subjects older than 50 years of age diagnosed with SH and/or DM. Participants underwent a complete ophthalmic examination including intraocular pressure (IOP) measurement by Goldmann tonometry and blood pressure measurement. The glaucoma diagnosis was confirmed by structural and functional evidence. Interviews and standardized questionnaires were used to evaluate participants’ lifestyle and other health conditions. Results: Among participants with DM/SH, 142 cases of POAG were confirmed for a prevalence of 5.6% [95% CI: 4.6 - 6.6], while 9.1% were glaucoma suspects [95% CI: 7.8% - 10.4%]. The majority of confirmed cases (77.5%) were undiagnosed. The prevalence of POAG was significantly higher with male gender, greater age, and diastolic blood pressure > 90 mmHg as risk factors. Conclusion: We found a high prevalence of POAG in patients with adequate SH and DM care in a novel Latino population. We also found great unawareness of the disease in this population. Our results have potentially enormous public health implications for Colombia and other Latino populations.

关键词： Open angle-glaucoma glaucoma Systemic Hypertension Diabetes Mellitus

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