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Plants’Steroidal Saponins‑A Review on Its Pharmacology Properties and analytical techniques

World Journal of Traditional Chinese Medicine 2022年第3期8卷 350-385页

作者： Sudha Porte Veenu Joshi Kamal Shah Nagendra Singh Chauhan Center for Basic Sciences Pt.Ravishankar Shukla UniversityRaipurChhattisgarhIndia Institute of Pharmaceutical Research GLA UniversityMathuraUttar PradeshIndia Drugs Testing Laboratory Avam Anusandhan KendraRaipurChhattisgarhIndia

The plant is a rich repository of useful secondary metabolites with profound medicinal ***,one type of bioactive compound,are amphitheatric glycosides with one and more hydrophilic sugar and hydrophobic steroidal and terpenoid *** former is known as steroidal saponin,and the latter is called terpenoid *** saponin is mostly distributed among monocotyledon families such as Asparagaceae,Amaryllidaceae,Dioscoreaceae,Smilacaceae,and *** though it is unusual,it could also be detected to some extent by dicotyledonous angiosperms,such as Plantaginaceae,Zygophyllaceae,Fabaceae,Asteraceae,and *** exhibits diverse pharmacological ability including antimicrobic,anti‑inflammatory,cAMP phosphodiesterase inhibitory,antiadipogenic,bactericide,cardioprotective,antitumor,antidiabetic,cytotoxic activity,antifungal,antiviral,antioxidant,and *** saponin timosaponin AIII from Anemarrhena asphodeloides has been found to possess antitumor ***,another steroidal sapogenin,has the potential of preventing neurological diseases by affecting different signaling pathways,increasing bone formation,and increasing antithrombotic *** A from Liriope platyphylla possesses anti‑inflammatory,antiasthma,and antiosteoclastogenic ***2 from Trillium tschonoskii exhibits anticancer *** cell cycle arrest and ROS‑dependent autophagy are induced by polyphyllin *** diverse biological activities of steroidal saponins are attributed to the variability of their structural *** of steroidal saponins in plant materials mainly utilizes classically and advances thin layer chromatography(TLC)on normal and reverses‑phase(high‑performance thin‑layer chromatography,densitometric TLC),gas chromatography,LC,UPLC,ultra‑high‑performance liquid chromatography(HPLC),supercritical fluid chromatography,and HPLC coupled to ultraviolet detector and diode array *** coupled with

关键词： Steroidal Saponins Glycosides Antitumour Antioxidant analytical techniques

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Recent Progress in Interfacial Dipole Engineering for Perovskite Solar Cells

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Nano-Micro Letters 2023年第10期15卷 260-286页

作者： Yinyi Ma Jue Gong Peng Zeng Mingzhen Liu School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China State Key Laboratory Electronic Thin Film and Integrated Devices University of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China

Design and modification of interfaces have been the main strategies in developing perovskite solar cells(PSCs). Among the interfacial treatments, dipole molecules have emerged as a practical approach to improve the efficiency and stability of PSCs due to their unique and versatile abilities to control the interfacial properties. Despite extensive applications in conventional semiconductors, working principles and design of interfacial dipoles in the performance/stability enhancement of PSCs are lacking an insightful elucidation. In this review, we first discuss the fundamental properties of electric dipoles and the specific roles of interfacial dipoles in PSCs. Then we systematically summarize the recent progress of dipole materials in several key interfaces to achieve efficient and stable PSCs. In addition to such discussions, we also dive into reliable analytical techniques to support the characterization of interfacial dipoles in PSCs. Finally, we highlight future directions and potential avenues for research in the development of dipolar materials through tailored molecular designs. Our review sheds light on the importance of continued efforts in this exciting emerging field, which holds great potential for the development of high-performance and stable PSCs as commercially demanded.

关键词： Perovskite solar cells Interfacial dipoles analytical techniques

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A review of traditional and novel detection techniques for melamine and its analogues in foods and animal feed

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Frontiers of Chemical Science and Engineering 2009年第4期3卷 427-435页

作者： Mengshi LIN Food Science Program Division of Food Systems&BioengineeringUniversity of MissouriColumbiaMO 65211USA

Melamine,a nitrogen-rich chemical,has received much attention in recent years due to a series of highly publicized food safety incidents,including 2007 pet food recalls in North America and 2008 melamine contamination in milk,infant formula,and other milkderived products in *** analytical methods for testing melamine are time-consuming,expensive,and ***,there is an increasing interest in the food science and analytical chemistry field to develop simple,quick,sensitive,and cost-effective methods for detection of melamine and its analogues(e.g.,cyanuric acid,melamine cyanurate,ammelide,and ammeline)in food ingredients,processed food,and animal *** review aims to summarize traditional and novel analytical techniques that have been used or show great potential to detect,characterize,and quantify melamine and its analogues in foods and animal feed.

关键词： analytical techniques melamine cyanuric acid food animal feed

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A Review on Pharmacological and analytical Aspects of Naringenin

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Chinese Journal of Integrative Medicine 2018年第7期24卷 551-560页

作者： Kanika Patel Gireesh Kumar Singh Dinesh Kumar Patel G.L.A Institute of Pharmaceutical Research MathuraIndia Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasi-221005India

Flavonoids are a widely distributed group of phytochemicals having benzo-pyrone nucleus, and more than 4,000 different flavonoids have been described and categorized into flavonols, flavones, flavanones, isoflavones, catechins and anthocyanidins. Flavonoids occurs naturally in fruits, vegetables, nuts, and beverages such as coffee, tea, and red wine, as well as in medical herbs. Flavonoids are responsible for the different colors of plant parts and are important constituents of the human diet. Flavanoids have different pharmacological activities, such as antioxidant, anti-allergic, antibacterial, anti-inflammatory, antimutagenic and anticancer activity. Naringenin belongs to the flavanones and is mainly found in fruits（grapefruit and oranges） and vegetables. Pharmacologically, it has anticancer, antimutagenic, anti-inflammatory, antioxidant, antiproliferative and antiatherogenic activities. Naringenin is used for the treatments of osteoporosis, cancer and cardiovascular diseases, and showed lipid-lowering and insulin-like properties. In the present review, detailed pharmacological and analytical aspects of naringenin have been presented, which revealed the impressive pharmacological profile and the possible usefulness in the treatment of different types of diseases in the future. The information provided in this communication will act as an important source for development of effective medicines for the treatment of various disorders.

关键词： analytical techniques flavonoids naringenin pharmacological activity phytoconstituents

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A Review on Pharmacological and analytical Aspects of Diosmetin:A Concise Report

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Chinese Journal of Integrative Medicine 2013年第10期19卷 792-800页

作者： Kanika Patel Manoj Gadewar Vijay Tahilyani Dinesh Kumar Patel GLA Institute of Pharmaceutical Research Mathura(281406)India SKIPS Warangal-Andhra Pradesh(506015)India Sonekar College of Pharmacy KoradiNagpur(440001)India Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasi(221005)India

Plants have been used as a source for food material and natural remedies for the treatment of vast range of diseases. Nature provides us remedies for the treatment of various types of disorders ranging from simpte aitments to complicated diseases. Plants are known to possess different pharmacological activities due to the presence of various phytoconstituents, Flavonoids are one of the main active phytoconstituents found in fruits, vegetables, wines, tea and cocoa. Flavonoids exhibit various pharmacological activities such as antioxidant, anti-inflammatory, anti-allergic, antibacterial, oestrogenic, cytotoxic antitumoural, hepatoprotective, antithrombotic and antiviral activity. Diosmetin （3＇, 5, 7-trihydroxy-4＇-methoxyflavone）, the aglycone part of the flavonoid glycosides diosmin occurs naturally in citrus fruit. Although it is found in herbal medicines and plays an important role in the treatment of various ailments, only limited scientific researches have been conducted. The aim of this review is to collect all available scientific literature published on diosmetin and combine it into this paper. This review contains an overview of pharmacological activities, isolation techniques and analytical techniques for diosmetin. Thus, valuable information provided in the present review will help researchers in developing alternative methods for the treatment of diseases from diosmetin.

关键词： analytical techniques diosmetin flavonoid pharmacological activity phytoconstituents

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Medicinal significance,pharmacological activities,and analytical aspects of ricinine:A concise report

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Journal of Coastal Life Medicine 2016年第8期4卷 663-667页

作者： Kanika Patel Dinesh Kumar Patel Jubilant Life Sciences NoidaUttar Pradesh 201301India Department of Pharmacy Galgotias UniversityGreater Noida 203201Uttar PradeshIndia

Ricinine(3-cyano-4-methoxy-N-methyl-2-pyridone)is an alkaloid present in leaves and seeds of castor plant *** *** can cause vomiting,convulsions,hypotension,liver and kidney damage and several other complications in *** presents mainly in young plant and it is the only cyano-substituted pyridine compounds occurred *** also found in some other plants such as Piper nigrum,Discocleidion rufescens,Aparisthmium cordatum and Nicotiana *** and intended Ricinus communis intoxications in humans and animals have been known for *** the present review,we summarize the information regarding its medicinal uses,pharmacological activities,analytical techniques and intended and unintended poisoning cases in humans and *** review will be beneficial for the researcher in the field of herbal medicine and other allied sciences.

关键词： analytical techniques Pharmacological activities Poisoning Ricinine Ricinus communis

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A review on pharmacological and analytical aspects of diosgenin:a concise report

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Natural Products and Bioprospecting 2012年第2期2卷 46-52页

作者： Kanika PATEL Manoj GADEWAR Vijay TAHILYANI Dinesh Kumar PATEL G.L.A Institute of Pharmaceutical Research MathuraIndia S.K.I.P.S.Warangal A.P.India Sonekar College of Pharmacy KoradiNagpurIndia Department of Pharmaceutics Institute of TechnologyBanaras Hindu UniversityVaranasi 221005India

Diosgenin is a steroidal sapogenin found in plants such as Dioscorea nipponoca,Solanum incanum,Solanum xanthocarpum and Trigonella foenum ***,biologically active phytochemicals have been used for the treatment of various types of disorder such as leukemia,inflammation,hypercholesterolemia and *** is also able to prevent bone loss to the same extent as that of *** is a typical initial intermediate for synthesis of steroidal compounds,oral contraceptives and sex ***,Costus and Trigonella are mainly used for the production of *** the basis of literature survey it divulges that diosgenin has very impressive pharmacological profile and could be used as a medicine for the treatment of different types of disorders in the ***,the present work aims to provide collective information in concern with its pharmacological activity and phytoanalytical *** review will be beneficial to researches for the development of an alternative method for the treatment of innumerable diseases from diosgenin.

关键词： analytical techniques cancer diosgenin pharmacological activity plant source seperation techniques

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