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检索条件"主题词=Aminoacylation"
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Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNA^(Lys)
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Science China(Life Sciences) 2020年 第8期63卷 1227-1239页
作者： Yong Wang Jing-Bo Zhou Qi-Yu Zeng Siqi Wu Mei-Qin Xue Pengfei Fang En-Duo Wang Xiao-Long Zhou State Key Laboratory of Molecular Biology CAS Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China State Key Laboratory of Bioorganic and Natural Products Chemistry Center for Excellence in Molecular SynthesisShanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China
Aminoacyl-tRNA synthetases(aaRSs)are ubiquitously expressed,essential enzymes,synthesizing aminoacyl-tRNAs for protein synthesis.Functional defects of aaRSs frequently cause various human disorders.Human KARS encodes ... 详细信息
来源： 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
线粒体RNAm^(3)C修饰酶METTL8的活力依赖于亚型特异的N-末端延伸结构且METTL8能修饰多种非天然底物tRNA
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科学通报:英文版 2023年 第18期68卷 2094-2105,M0004页
作者： 黄梦涵 王金涛 张剑辉 毛雪玲 彭桂鑫 林秀颖 吕岱竹 袁晨 林桓 王恩多 周小龙 Key Laboratory of RNA Science and Engineering State Key Laboratory of Molecular BiologyCAS Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China Key Laboratory of Systems Health Science of Zhejiang Province School of Life ScienceHangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China State Key Laboratory of Marine Resource Utilization in South China Sea Hainan UniversityHaikou 570228China School of Life Sciences Hainan UniversityHaikou 570228China Analysis and Testing Center Chinese Academy of Tropical Agricultural SciencesHaikou 571101China School of Pharmacy China Pharmaceutical UniversityNanjing 211198China
定位于线粒体的METTL8-Iso1和分布在核仁的METTL8-Iso4均为甲基转移酶基因METTL8通过mRNA选择性剪接产生的亚型,它们的区别仅为前者有N-末端延伸结构.METTL8-Iso1的功能是催化产生线粒体tRNATh和tRNASe(UCN)第32位3-甲基胞苷(mC32)修饰.... 详细信息
来源： 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Effect of Rare Earth Ions on Kinetic Properties of Escherichia coli Leucyl-tRNA Synthetase
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Journal of Rare Earths 2000年 第3期18卷 224-228页
作者： 涂华民 杨燕生 李勇 王恩多 Department of Chemistry Hebei Normal University Shijiazhuang 050091 China Department of Chemistry Zhongshan University Guangzhou 510275 China State-Key Laboratory of Molecular Biology Shanghai Institute of Biochemistry Chinese Academy of Sciences Shanghai 200031 China
Escherichia coli leucyl-tRNA synthetase (LeuRS) is one of aminoacyl-tRNA synthetases (aaRSs) and belongs to class 1 aaRSs. The apparent steady-state kinetics of the aminoacylation reaction catalyzed by LeuRS in the pr... 详细信息
来源： 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
The role of polysaccharides in the molecular evolution of biopolymers
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Natural Science 2014年 第2期6卷 59-70页
作者： Aleksander N. Zimnitskii Sergey A. Bashkatov Vadym N. Urazbaev Aleksey V. Chemeris Renat S. Yamidanov Bashkir State University Ufa Russia Biochemistry and Genetics Institute of Russian Academy of Sciences Ufa Russia Institute of Organic Chemistry Russian Academy of Sciences Ufa Russia Research and Production Association “Plazan” Moscow Russia
The empirical (biochemical, the PCR method) and computational (quantum-chemical, PM3) methods have shown the ability of polysaccharides to catalyze the polymerization of amino acids and nucleotides within the physiolo... 详细信息
来源： 维普期刊数据库 维普期刊数据库 评论
Theoretical and experimental biology in one<br>—A symposium in honour of Professor Kuo-Chen Chou’s 50th anniversary and Professor Richard Giegé’s 40th anniversary of their scientific careers
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Journal of Biomedical Science and Engineering 2013年 第4期6卷 435-442页
作者： Sheng-Xiang Lin Jacques Lapointe Department of Biochemistry Microbiology and Bioinformatics and PROTEO Laval University Quebec Canada Laboratory of Molecular Endocrinology and Oncology Research Center of Laval University Hospital Center (CHUQ-CHUL) and PROTEO Laval University Quebec Canada
It has been a dream that theoretical biology can be extensively applied in experimental biology to accelerate the understanding of the sophiscated movements in living organisms. A brave assay and an excellent example ... 详细信息
来源： 维普期刊数据库 维普期刊数据库 评论
Human mitochondrial threonyl-t RNA synthetase and disease
Human mitochondrial threonyl-t RNA synthetase and disease
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中国生物化学与分子生物学会2016年全国学术会议
作者： Xiao-Long Zhou Yong Wang Zhi-Rong Ruan Ru-Juan Liu Gilbert Eriani En-Duo Wang State Key Laboratory of Molecular Biology Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences University of Chinese Academy of Sciences Architecture et Réactivité de l'ARN Université e Strasbou rgdUPR9002 CNRS Institut de Biologie Moléculaire et Cellulaire 15 rue René Descartes
Mitochondria require all translational components,including aminoacyl-t RNA synthetases(aa RSs),to complete organelle protein synthesis.Some aa RS mutations caused mitochondrial disorders,including human mitochondrial... 详细信息
来源： cnki会议 评论
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