检索结果-南通市图书馆

Investigation of the processing technology and mechanism of Kansui radix by licorice based on response surface methodology and integrative pharmacology

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Traditional Medicine Research 2021年第3期6卷 5-15页

作者： Xiao-Yan Zhang Xiao-Juan Su Chen-Xu Ning Xiang-Long Meng Shuo-Sheng Zhang College of Chinese Materia Medica and Food Engineering Shanxi University of Chinese MedicineJinzhong 030619China

Background:The herbs should be processed by different methods before use,and the efficacy and toxicity of Chinese herbal medicines may change,which may enhance efficacy and reduce toxicity after ***(Kansui radix)is a common clinical herbal medicine,and there are considerable changes in its toxicity and efficacy after ***(Glycyrrhizae radix et rhizome)has a detoxifying ***:Using the contents of euphorbiadienol and the alcohol-soluble extract of Glycyrrhizae radix-processed Kansui radix as evaluation indexes,response surface methodology was used to optimize the processing technology of Kansui radix by exploring the effects of Glycyrrhizae radix et rhizoma-addition amount,frying temperature,and frying time on the processing technology of Kansui ***,response surface software was used to analyze experimental data to determine the processing parameters of Kansui radix by Glycyrrhizae radix et *** Pharmacology-based Research Platform of Traditional Chinese Medicine is used to analysis the potential ingredients of Kansui radix and verify the potential ingredients by western ***:The technology of Glycyrrhizae radix et rhizoma-processed Kansui radix was optimized for the Glycyrrhizae radix et rhizoma-addition amount of 27%,frying temperature of 180℃,and frying time of 11 *** network pharmacology analysis revealed that Kansui radix could cause kidney,liver,and heart injury by the PI3K/AKT signaling *** radix at high or low dose could decrease the ratio of p-AKT/AKT while Glycyrrhizae radix et rhizoma-processed Kansui could increase ***:The model established by response surface methodology is relatively accurate and can predict the contents of euphorbiadienol and alcohol extract of processed Kansui *** toxic effects and its mechanism of action of Kansui radix and processed Kansui radix on kidney,liver,and heart,from the perspective of systems biology,have provided scie

关键词： Kansui Response surface methodology Processing technology Euphadienol alcohol extract Network pharmacology

A preliminary study on the anti-inflammatory and analgesic effects of two extracts of pine pollen on anoxia and fatigue resistance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

TMR Aging 2020年第2期2卷 59-66页

作者： Shi-Bo Zhao Suo-Yi Huang Yu-Xin Wei Zhong-Gang Wu Han-Jun Ma Xue-Ying Yu Hui-Man Yang Yi-Jie Wang Yu-Zhu Zeng College of Clinical Medicine Youjiang Medical University For NationalitiesBaise 533000China College of Pharmacy Youjiang Medical University for NationalitiesBaise 533000China Key Laboratory of Guangxi's College for the Study of Characteristic Medicine in Youjiang River Basin Youjiang Medical University for NationalitiesBaise 533000China College of Basic Medicine Youjiang Medical University for NationalitiesBaise 533000China College of Medical Imaging Youjiang Medical University for NationalitiesBaise 533000China

Background:To study the anti-inflammatory,analgesic,fatigue resistant and antihypoxia effects of ethanol extract and water extract of pine ***:Two different extracts of pine pollen were prepared into there different concentrations,that is 1.5 mg·mL^-1,4.5 mg·mL^-1 and 7.5 mg·mL^-1 *** extract were studied by xylene-induced ear swelling,acetic acid distortion test and hot plate *** antihypoxia and antifatigue effects were explored by weight-bearing swimming experiment,routine pressure hypoxia tolerance experiment and liver weight coefficient ***:Through the study of the four pharmacological effects of ethanol extract and water extract,we found that the anti-inflammatory,analgesic,antithyposia and antifatigue effects of ethanol extract were better than that of water ***,the experimental effects significantly improved with the increase of the concentration,and the effect of alcohol increased dose group was accurate(P<0.05).Conclusion:Pine pollen has excellent effects of anti-inflammatory,analgesic,antihypoxia and ***,with the increase of drug concentration,effects tend to be more obvious with positive correlation.

关键词： Pine pollen alcohol extract Water extract Anti-inflammatory effect Analgesic effect Antihypoxia Fatigue resistance

alcohols extraction Process and Content of Active Ingredients in Chinese Northeastern Auricularia auricula

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Medicinal Plant 2018年第4期9卷 41-45页

作者： Xianghui KONG Guoli YANG Xijun CHEN Hui WANG Dan CHEN Institute of Microbiology Heilongjiang Academy of Sciences Institute of Advanced Technology Heilongjiang Academy of Sciences Heilongjiang Engineering Technology Research Center of Black Fungus Resource Utilization Heilongjiang Johnsun Biological Engineering Co. Ltd. Heilongjiang Engineering Technology Research Center of Mycomedicine

[Objectives] The aim was to study the type and content of alcohol-soluble active ingredients in Auricularia auricula. [Methods]With total yield of alcohol extract as an indicator,the optimal concentrations of ethanol,isopropanol and n-butanol for alcohol extraction of A. auricula powder were determined. The contents of total flavonoids,polyphenols and triterpenoids in three different alcohol extracts of A. auricula,as well as in the alcohol extracts of polysaccharides and melanin extraction residue of A. auricula were determined. [Results] When90% ethanol was used,the yield of alcohol extract of A. auricula was 10. 7%. In the alcohol extract,the contents of total flavonoids,polyphenols and triterpenoids were 5. 68 mg/100 g,0. 43% and 0. 55%,respectively. When 100% isopropanol was used,the yield of alcohol extract was 10. 1%. In the alcohol extract,the contents of total flavonoids,polyphenols and triterpenoids were 4. 84 mg/100 g,0. 66% and 0. 37%,respectively. When 70% n-butanol was used,the yield of alcohol extract was 5. 4%. In the alcohol extract,the contents of total flavonoids,polyphenols and triterpenoids were 4. 07 mg/100 g,1. 68% and 0. 30%,respectively. The yields of ethanol,isopropanol and n-butanol extracts of polysaccharide and melanin extraction residue of A. auricula were 13. 8%,14. 3% and 8. 9%,respectively. In the three kinds of alcohol extracts,the contents of total flavonoids were 8. 28,11. 99,and 12. 38 mg/100 g,respectively; the contents of polyphenols were 0.14%,0. 38% and 0. 75%,respectively; and the contents of triterpenoids were 0. 25%,0. 60% and 0. 58%,respectively. [Conclusions]This study will provide certain reference for the in-depth study and development and utilization of active ingredients in A. auricula.

关键词： Auricularia auricula alcohol extract Total flavonoids Polyphenols Triterpenoids

Analysis and Study on Quality Control of Yao Medicine Damnacanthus macrophyllus Based on Methods in Chinese Pharmacopoeia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Medicinal Plant 2021年第2期12卷 40-43页

作者： Jiangcun WEI Xiumei MA Yanxiu WANG Bihua NONG Chunli TANG Jingrong LU Fengxian ZHAO Guangxi International Zhuang Medicine Hospital Nanning 530201 China The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning 530023 China

[Objectives]To establish a quality analysis method for Yao medicine Damnacanthus macrophyllus *** ***(Makino)Koidz..[*** *** Makino].[Methods]The moisture,total ash and alcohol extracts of *** medicinal materials were determined according to the experimental methods in the Chinese Pharmacopoeia(2020).[Results]All the 10 batches of *** medicinal materials from different collection times and different regions in Guangxi had the same plant morphological *** experimental results indicate that the moisture was 9.81%-11.52%,the total ash content was 7.37%-9.53%,the acid-insoluble ash content was 1.10%-1.97%,and the extract was 8.25%-10.22%.[Conclusions]This study provides a scientific basis for establishing a quality standard for Yao medicine *** medicinal materials,and it is expected to better utilize and develop ***.

关键词： Damnacanthus macrophyllus Sieb.ex Miq.var.giganteus(Makino)Koidz..[D.indicus Gaertn.f.var.giganteus Makino] Moisture Total ash content alcohol extract Quality analysis