检索结果-南通市图书馆

Role of Adipose tissue grafting and adipose-derived stem cells in peripheral nerve surgery

Neural Regeneration Research 2022年第10期17卷 2179-2184页

作者： Tiam M.Saffari Sara Saffari Krishna S.Vyas Samir Mardini Alexander Y.Shin Department of Orthopedic Surgery Division of Microvascular and Hand SurgeryMayo ClinicRochesterMNUSA Radboud University Medical Center Radboud Institute for Health SciencesDepartment of Plastic SurgeryNijmegenThe Netherlands Department of Surgery Division of Plastic and Reconstructive SurgeryMayo ClinicRochesterMNUSA

The application of autologous fat grafting in reconstructive surgery is commonly used to improve functional form.This review aims to provide an overview of the scientific evidence on the biology of Adipose tissue,the role of adipose-derived stem cells,and the indications of Adipose tissue grafting in peripheral nerve surgery.Adipose tissue is easily accessible through the lower abdomen and inner thighs.Non-vascularized Adipose tissue grafting does not support oxidative and ischemic stress,resulting in variable survival of adipocytes within the first 24 hours.Enrichment of Adipose tissue with a stromal vascular fraction is purported to increase the number of adipose-derived stem cells and is postulated to augment the long-term stability of Adipose tissue grafts.Basic science nerve research suggests an increase in nerve regeneration and nerve revascularization,and a decrease in nerve fibrosis after the addition of adipose-derived stem cells or Adipose tissue.In clinical studies,the use of autologous lipofilling is mostly applied to secondary carpal tunnel release revisions with promising results.Since the use of adipose-derived stem cells in peripheral nerve reconstruction is relatively new,more studies are needed to explore safety and long-term effects on peripheral nerve regeneration.The Food and Drug Administration stipulates that adipose-derived stem cell transplantation should be minimally manipulated,enzyme-free,and used in the same surgical procedure,e.***.Adipose tissue grafts that contain native adipose-derived stem cells or stromal vascular fraction.Future research may be shifted towards the use of tissue-engineered Adipose tissue to create a supportive microenvironment for autologous graft survival.Shelf-ready alternatives could be enhanced with adipose-derived stem cells or growth factors and eliminate the need for Adipose tissue harvest.

关键词： Adipose tissue adipose-derived stem cells angiogenesis autologous fat grafting nerve injury nerve regeneration paracrine environment peripheral nerve reconstruction stem cell secretome tissue engineering

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of high‑grain diet feeding on fatty acid profiles in milk,blood,muscle,and Adipose tissue,and transcriptional expression of lipid‑related genes in muscle and Adipose tissue of dairy cows

引用

畜牧与生物技术杂志:英文版 2023年第5期14卷 2063-2078页

作者： Qiaorong Cui Limei Lin Zheng Lai Shengyong Mao Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health Laboratory of Gastrointestinal MicrobiologyCollege of Animal Science and TechnologyNanjing Agricultural UniversityNanjingJiangsu Province 210095China National Center for International Research on Animal Gut Nutrition Nanjing Agricultural UniversityNanjing 210095China National Experimental Teaching Demonstration Center of Animal Science Nanjing Agricultural UniversityNanjing 210095China

Background High-grain(HG)diets affect lipid metabolism in the liver and mammary tissue of dairy cows,but its effects on muscle and Adipose tissue have not been wide evaluated.Thus,the aim of this study is to clarify this issue.Methods Twelve Holstein cows were randomly divided into two groups:conventional diet group(CON,n=6)and the HG diet group(n=6).On day 7 of week 4,rumen fluid was sampled to measure pH,milk was sampled to meas-ure components,and blood was sampled to measure biochemical parameters and fatty acid composition.After the experiment,cows were slaughtered to collect muscle and Adipose tissue for fatty acid composition and transcriptome analysis.Results HG feeding decreased the ruminal pH,milk’s fat content and long-chain fatty acid proportion(Ptissue,HG feeding tended to increase the triacylglycerol(TG)concentration(PAdipose tissue,HG feeding increased the concentration of TG and decreased the concentration of C18:1 cis9(PAdipose tissue,HG feeding increased TG concentration and up-regulated the expression of genes related to adipogenesis,while down-regulated the expression of genes related to lipid transport.These results complement our knowledge of the fatty acid composi-tion of muscle and adipose ti

关键词： Adipose tissue Fatty acid composition High-grain diets Lipid transcriptional profiles Muscle tissue

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Activating Connexin43 gap junctions primes Adipose tissue for therapeutic intervention

引用

Acta Pharmaceutica Sinica B 2022年第7期12卷 3063-3072页

作者： Yi Zhu Na Li Mingyang Huang Xi Chen Yu AAn Jianping Li Shangang Zhao Jan-Bernd Funck Jianhong Cao Zhenyan He Qingzhang Zhu Zhuzhen Zhang Zhao VWang Lin Xu Kevin W.Williams Chien Li Kevin Grove Philipp E.Scherer Touchstone Diabetes Center Department of Internal Medicinethe University of Texas Southwestern Medical Center at DallasDallasTX 75390USA Division of Cardiology Department of Internal Medicinethe University of Texas Southwestern Medical Center at DallasDallasTX 75390USA Division of Hypothalamic Research Department of Internal Medicinethe University of Texas Southwestern Medical Center at DallasDallasTX 75390USA Quantitative Biomedical Research Center Department of Population and Data Sciencesthe University of Texas Southwestern Medical Center at DallasDallasTX 75390USA Department of Pediatrics the University of Texas Southwestern Medical Center at DallasDallasTX 75390USA Novo Nordisk Research Center SeattleWA 98109USA Children’s Nutrition Research Center Department of PediatricsBaylor College of MedicineHoustonTX 77030USA Department of Cell Biology the University of Texas Southwestern Medical Center at DallasDallasTX 75390USA

Adipose tissue is a promising target for treating obesity and metabolic diseases.However,pharmacological agents usually fail to effectively engage adipocytes due to their extraordinarily large size and insufficient vascularization,especially in obese subjects.We have previously shown that during cold exposure,connexin43(Cx43)gap junctions are induced and activated to connect neighboring adipocytes to share limited sympathetic neuronal input amongst multiple cells.We reason the same mechanism may be leveraged to improve the efficacy of various pharmacological agents that target Adipose tissue.Using an Adipose tissue-specific Cx43 overexpression mouse model,we demonstrate effectiveness in connecting adipocytes to augment metabolic efficacy of theβ_(3)-adrenergic receptor agonist Mirabegron and FGF21.Additionally,combing those molecules with the Cx43 gap junction channel activator danegaptide shows a similar enhanced efficacy.In light of these findings,we propose a model in which connecting adipocytes via Cx43 gap junction channels primes Adipose tissue to pharmacological agents designed to engage it.Thus,Cx43 gap junction activators hold great potential for combination with additional agents targeting Adipose tissue.

关键词： GJA1 Adipose tissue Gap junction Connexin43 FGF21 β3-Adrenergic receptor agonist Obesity Type 2 diabetes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Vitamin A regulates intramuscular Adipose tissue and muscle development:promoting high-quality beef production

引用

Journal of Animal Science and Biotechnology 2021年第3期12卷 1138-1147页

作者： Dong Qiao Peng Stephen B.Smith Hong Gu Lee Department of Animal Science and Technology Sanghuh College of Life SciencesKonkuk UniversitySeoul 05029South Korea Department of Animal Science Texas A&M UniversityCollege StationTX 77843USA

During growth in cattle,the development of intramuscular Adipose tissue and muscle is dependent upon cell hyperplasia(increased number of adipocytes)and hypertrophy(increased size of adipocytes).Based on the results of previous studies,other Adipose tissue depots(e.g.,perirenal and subcutaneous)develop from the fetal stage primarily as brown Adipose tissue.The hyperplastic stage of intramuscular adipose is considered to develop from late pregnancy,but there is no evidence indicating that intramuscular Adipose tissue develops initially as brown Adipose tissue.Hyperplastic growth of intramuscular adipose continues well into postweaning and is dependent on the timing of the transition to grain-based diets;thereafter,the late-stage development of intramuscular Adipose tissue is dominated by hypertrophy.For muscle development,hyperplasia of myoblasts lasts from early(following development of somites in the embryo)to middle pregnancy,after which growth of muscle is the result of hypertrophy of myofibers.Vitamin A is a fat-soluble compound that is required for the normal immunologic function,vision,cellular proliferation,and differentiation.Here we review the roles of vitamin A in intramuscular Adipose tissue and muscle development in cattle.Vitamin A regulates both hyperplasia and hypertrophy in in vitro experiments.Vitamin A supplementation at the early stage and restriction at fattening stage generate opposite effects in the beef cattle.Appropriate vitamin A supplementation and restriction strategy increase intramuscular Adipose tissue development(i.e.,marbling or intramuscular fat)in some in vivo trials.Besides,hyperplasia and hypertrophy of myoblasts/myotubes were affected by vitamin A treatment in in vitro trials.Additionally,some studies reported an interaction between the alcohol dehydrogenase-1C(ADH1C)genotype and vitamin A feed restriction for the development of marbling and/or intramuscular Adipose tissue,which was dependent on the timing and level of vitamin A restriction.Therefore,the feed strategy of vitam

关键词： Adipose tissue Cattle Intramuscular Adipose tissue Muscle development Vitamin A

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A proposed modulatory role of the endocannabinoid system on Adipose tissue metabolism and appetite in periparturient dairy cows

引用

Journal of Animal Science and Biotechnology 2021年第3期12卷 995-1007页

作者： Madison N.Myers Maya Zachut Joseph Tam G.Andres Contreras Department of Large Animal Clinical Sciences College of Veterinary MedicineMichigan State UniversityEast LansingMI 48824USA Department of Ruminant Science Institute of Animal SciencesAgricultural Research Organization/Volcani Center7505101 Rishon LeZionIsrael Obesity and Metabolism Laboratory The Institute for Drug ResearchSchool of PharmacyFaculty of MedicineThe Hebrew University of Jerusalem9112001 JerusalemIsrael

To sustain the nutrient demands of rapid fetal growth,parturition,and milk synthesis,periparturient dairy cows mobilize Adipose tissue fatty acid stores through lipolysis.This process induces an inflammatory response within AT that is resolved as lactation progresses;however,excessive and protracted lipolysis compounds the risk for metabolic and inflammatory diseases.The suppression of lipolytic action and inflammation,along with amplification of adipogenesis and lipogenesis,serve as prospective therapeutic targets for improving the health of periparturient dairy cows.Generally,the activation of cannabinoid receptors by endocannabinoids enhances adipogenesis and lipogenesis,suppresses lipolysis,and increases appetite in mammals.These biological effects of activating the endocannabinoid system open the possibility of harnessing the endocannabinoid system through nutritional intervention in dairy herds as a potential tool to improve dairy cows’health,although much is still to be revealed in this context.This review summarizes the current knowledge surrounding the components of the endocannabinoid system,elaborates on the metabolic effects of its activation,and explores the potential to modulate its activity in periparturient dairy cows.

关键词： Adipogenesis Adipose tissue Dairy cow health Endocannabinoids Endocannabinoid system Lipogenesis Lipolysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Identification and characterization of murine Adipose tissue-derived somatic stem cells of Shenque(CV8)acupoint

引用

Chinese Medical Journal 2021年第22期134卷 2730-2737页

作者： Yu-Hui Hao Zhi-Zhen Liu Hong Zhao Lei Wang Ajab Khan Jian-Bin Mu Yu-Fei Wang Li-Hong Yang Ran Zhou Jun Xie Shanxi Key Laboratory of Birth Defect and Cell Regeneration Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Basic Medicine Xinzhou Vocational and Technical CollegeXinzhouShanxi 034000China Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaMA 20852USA Basic Medical College Shanxi University of Chinese MedicineJinzhongShanxi 030619China.

Background:Shenque(CV8)acupoint is located on the navel and has been therapeutically used for more than 2000 years in Traditional Chinese Medicine(TCM).However,clinical research on the underlying therapeutic molecular mechanisms of the CV8 acupoint lags far behind.This study aimed to study the mechanisms of umbilical acupoint therapy by using stem cells.Methods:The morphological characteristics of CV8 acupoint were detected under a stereomicroscope using hematoxylin and eosin(H&E)staining.Oil Red,Masson,and immunohistochemical staining on multi-layered slices were used to identify the type of cells at the CV8 acupoint.Cell proliferation was measured by a cell counting kit-8(CCK-8)method.Flow cytometry and immunohistochemistry were used for cell identification.Induced differentiation was used to compare the differentiation of cells derived from CV8 acupoint and non-acupoint somatic stem cells into other cell types,such as osteogenic,adipogenic,and neural stem cell-like cells.Results:Morphological observations showed that Adipose tissues at the linea alba of the CV8 acupoint in mice had a mass-like distribution.Immunohistochemical staining confirmed the distribution of stem cell antigen-1(Sca-1)positive cells in the multi-layered slices of CV8 acupoint tissues.Cells isolated from Adipose tissues at the CV8 acupoint exhibited high expression of Sca-1 and CD44 and low expression of CD31 and CD34,and these cells possessed osteogenic,adipogenic,and neurogenic stem cell-like cell differentiation ability.The cell proliferation(day 4:0.5138±0.0111 vs.0.4107±0.0180,t=8.447,P=0.0011;day 5:0.6890±0.0070 vs.0.5520±0.0118,t=17.310,P100 mm:2.6000±0.5477 vs.

关键词： Shenque(CV8)acupoint Non-acupoint site Navel Adipose tissue Somatic stem cells Stem cell antigen-1(Sca-1) Umbilical therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Transcriptional changes in mesenteric and subcutaneous Adipose tissue from Holstein cows in response to plane of dietary energy

引用

Journal of Animal Science and Biotechnology 2018年第1期9卷 233-247页

作者： S.J.Moisá P.Ji J.K.Drackley S.L.Rodriguez-Zas J.J.Loor Department of Animal Sciences Auburn University Department of Animal Sciences University of Illinois

Background： Dairy cows can readily overconsume dietary energy during most of the prepartum period, often leading to higher prepartal concentrations of insulin and glucose and excessive body fat deposition. The end result of these physiologic changes is greater Adipose tissue lipolysis post-partum coupled with excessive hepatic lipid accumulation and compromised health. Although transcriptional regulation of the adipose response to energy availability is well established in non-ruminants, such regulation in cow Adipose tissue depots remains poorly characterized.Results： Effects of ad-libitum access to high [HIGH; 1.62 Mcal/kg of dry matter（DM）] or adequate（CON; 1.35 Mcal/kg of DM） dietary energy for 8 wk on mesenteric（MAT） and subcutaneous（SAT） Adipose tissue transcript profiles were assessed in non-pregnant non-lactating Holstein dairy cows using a 13,000-sequence annotated bovine oligonucleotide microarray. Statistical analysis revealed 409 and 310 differentially expressed genes（DEG） due to tissue and diet. Bioinformatics analysis was conducted using the Dynamic Impact Approach（DIA） with the KEGG pathway database. Compared with SAT, MAT had more active biological processes related to Adipose tissue accumulation（adiponectin secretion） and signs of pro-inflammatory processes due to Adipose tissue expansion and macrophage infiltration（generation of ceramides）. Feeding the HIGH diet led to changes in m RNA expression of genes associated with cell hypertrophy（regucalcin）, activation of adipogenesis（phospholipid phosphatase 1）,insulin signaling activation（neuraminidase 1） and angiogenesis（semaphorin 4 G, plexin B1）. Further, inflammation due to HIGH was underscored by m RNA expression changes associated with oxidative stress response（coenzyme Q3, methyltransferase）, ceramide synthesis（N-acylsphingosine amidohydrolase 1）, and insulin signaling（interferon regulatory factor 1, phosphoinositide-3-kinase regulatory subunit 1, retinoic acid receptor alpha）. Activation of ribosome in cows fed HIGH indicated the existence of

关键词： Adipose tissue Dairy cow Dietary energy Transcriptome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adipose tissue macrophage in immune regulation of metabolism

引用

Science China(Life Sciences) 2016年第12期59卷 1232-1240页

作者： Yifu Qiu Bo Shan Liu Yang Yong Liu Institute of Molecular Medicine Peking-Tsinghua Center for Life Sciences Peking University Beijing 100871 China Key Laboratory of Nutrition and Metabolism Institute for Nutritional Sciences Shanghai Institutes for Biological Sciences Chinese Academy of Sciences University of the Chinese Academy of Sciences Shanghai 200031 China Hubei Key Laboratory of Cell Homeostasis College of Life Sciences the Institute for Advanced Studies Wuhan University Wuhan 430072 China

The prevalence of obesity and type 2 diabetes is escalating to an epidemic proportion worldwide.Obesity is known to be associated with a state of chronic,low-grade inflammation.Emerging lines of evidence have shown that both innate and adaptive immune responses play crucial roles in the control of metabolic homeostasis.Macrophages in Adipose tissues are the essential effector cells in orchestrating metabolic inflammation,which is thought to promote the pathogenic progression of obesity and obesity-related disorders.Here we discuss our current understanding of the distinct modes of activation of Adipose tissue macrophages,which can sense the metabolic cues and exert profound effects upon adipose homeostasis.Targeting macrophages in Adipose tissues may provide new avenues for developing immunomodulation-based therapeutics against obesity and obesity-associated metabolic diseases.

关键词： macrophage Adipose tissue obesity inflammation metabolic disease

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Alisol B 23-acetate promotes white Adipose tissue browning to mitigate high-fat diet-induced obesity by regulating mTOR-SREBP1 signaling

引用

Journal of Integrative Medicine 2024年第1期22卷 83-92页

作者： Lu-lu Han Xin Zhang Hui Zhang Ting Li Yi-chen Zhao Ming-hui Tian Feng-lei Sun Bo Feng Department of Neurology Three The Fifth People’s Hospital of JinanJinan 250013Shandong ProvinceChina Department of Gastroenterology Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina The First Clinical Medical College Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of Geriatrics the First Affiliated Hospital of Shandong First Medical University(Shandong Provincial Qianfoshan Hospital)Jinan 250014Shandong ProvinceChina Chinese Medicine Culture and Literature Research Institute Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of General Medicine Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of Traditional Chinese Medicine the Second People’s Hospital of Haibei PrefectureZangzu Autonomous Prefecture of Haibei810300Qinghai ProvinceChina

Objective Obesity is a global health concern with management strategies encompassing bariatric surgery and anti-obesity drugs;however,concerns regarding complexities and side effects persist,driving research for more effective,low-risk strategies.The promotion of white Adipose tissue(WAT)browning has emerged as a promising approach.Moreover,alisol B 23-acetate(AB23A)has demonstrated efficacy in addressing metabolic disorders,suggesting its potential as a therapeutic agent in obesity management.Therefore,in this study,we aimed to investigate the therapeutic potential of AB23A for mitigating obesity by regulating metabolic phenotypes and lipid distribution in mice fed a high-fat diet(HFD).Methods An obesity mouse model was established by administration of an HFD.Glucose and insulin metabolism were assessed via glucose and insulin tolerance tests.Adipocyte size was determined using hematoxylin and eosin staining.The expression of browning markers in WAT was evaluated using Western blotting and quantitative real-time polymerase chain reaction.Metabolic cage monitoring involved the assessment of various parameters,including food and water intake,energy metabolism,respiratory exchange rates,and physical activity.Moreover,oil red O staining was used to evaluate intracellular lipid accumulation.A bioinformatic analysis tool for identifying the molecular mechanisms of traditional Chinese medicine was used to examine AB23A targets and associated signaling pathways.Results AB23A administration significantly reduced the weight of obese mice,decreased the mass of inguinal WAT,epididymal WAT,and perirenal Adipose tissue,improved glucose and insulin metabolism,and reduced adipocyte size.Moreover,treatment with AB23A promoted the expression of browning markers in WAT,enhanced overall energy metabolism in mice,and had no discernible effect on food intake,water consumption,or physical activity.In 3T3-L1 cells,AB23A inhibited lipid accumulation,and both AB23A and rapamycin inhibited the mammalian target of rapamycin-sterol regulato

关键词： Obesity Alisol B 23-acetate Adipose tissue mTOR-SREBP1 High-fat diet

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Short-term intensive atorvastatin therapy improves endothelial function partly via attenuating perivascular Adipose tissue inflammation through 5-lipoxygenase pathway in hyperlipidemic rabbits

引用

Chinese Medical Journal 2014年第16期127卷 2953-2959页

作者： Wang Xiaoqiao Lin Yongqin Luo Niansang Chen Zhongqing Gu Miaoning Wang Jingfeng Chen Yangxin Department of Anaesthesiology Nanfang Hospital of Southern Medical University Guangzhou Guangdong 510515 China Department of Cardiology Sun Yat-sen Memorial Hospital of SunYat-sen University Guangzhou Guangdong 510120 China Guangdong Province Key Laboratory of Electrophysiology and Arrhythmia Guangzhou Guangdong 510120 China

Background Atherosclerosis is a kind of disease with multiple risk factors,of which hyperlipidemia is a major classical risk factor resulting in its pathogenesis and development.The aim of this study was to determine the effects of short-term intensive atorvastatin （IA） therapy on vascular endothelial function and explore the possible mechanisms that may help to explain the clinical benefits from short-term intensive statin therapy.Methods After exposure to high-fat diet （HFD） for 8 weeks,the animals were,respectively,treated with IA or low-dose atorvastatin （LA） for 5 days.Blood lipids,C-reactive protein （CRP）,tumor necrosis factor-α （TNF-α）,interleukin-6 （IL-6）,nitric oxide （NO）,endothelin-1 （ET-1）,and endothelium-dependent vasorelaxation function were,respectively,measured.mRNA and protein expression of CRP,TNF-α,IL-6,macrophage chemoattractant protein-1 （MCP-1）,and 5-lipoxygenase （5-LO） were also evaluated in pericarotid Adipose tissue （PCAT） and cultured adipocytes.Results HFD increased serum inflammatory factor levels; induced significant hyperlipidemia and endothelial dysfunction,including imbalance between NO and ET-1; enhanced inflammatory factors and 5-LO expression; and promoted macrophage infiltration into Adipose tissue.Five-day IA therapy could significantly decrease serum inflammatory factor levels and their expression in PCAT; restore the balance between NO and ET-1; and improve endothelial function and macrophage infiltration without significant changes in blood lipids.However,all of the above were not observed in LA therapy.In vitro experiment found that lipopolysaccharide （LPS） enhanced the expression of inflammatory factors and 5-LO in cultured adipocytes,which could be attenuated by short-time （6 hours） treatment of high-dose （5 pmol/L） but not low-dose （0.5 μmol/L） atorvastatin.In addition,inhibiting 5-LO by Cinnamyl-3,4-dihydroxy-α-cyanocinnamate （CDC,a potent and direct 5-LO inhibitor） could significantly downregulate the above-mentioned gene expression in LPS-treated adipocytes.Conclusion

关键词： atorvastatin endothelial function Adipose tissue inflammation 5-lipoxygenase pathway

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：