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Presence of three dengue serotypes in Ouagadougou(Burkina Faso):research and public health implications

Infectious Diseases of Poverty 2016年第1期5卷 208-220页

作者： Valéry Ridde Isabelle Agier Emmanuel Bonnet Mabel Carabali Kounbobr Roch Dabiré Florence Fournet Antarou Ly Ivlabèhiré Bertrand Meda Beatriz Parra Department of Social and Preventive Medicine University of Montreal School of Public Health(ESPUM)MontréalCanada University of Montreal Public Health Research Institute(IRSPUM) Pavillon 7101 Avenue du ParcP.O.Box 6128Centre-ville StationMontrealQuebec H3C 3J7Canada Identités et Différenciations de l’Environnement des Espaces et des Sociétés–Caen(IDEES) University of Caen Basse-NormandieCaenFrance International Vaccine Institute Dengue Vaccine InitiativeSNU Research Park1 Gwanak-roGwanak-guSeoul 151-742Korea Institut de Recherche en Sciences de la Santé(IRSS) B.P.545 Bobo-DioulassoBurkina Faso UnitéMaladies infectieuses et vecteurs:écologie génétiqueévolution et contrôle(MIVEGEC)Institut de recherche pour le développement(IRD)B.P.171 Bobo-DioulassoBurkina Faso Institut de Recherche en Sciences de la Santé(IRSS) 03 B.P.7192 OuagadougouBurkina Faso Grupo de Virus Emergentes y Enfermedad Departamento de Microbiología Universidad del ValleCaliColombia

Background:The significant malaria burden in Africa has often eclipsed other febrile *** Faso’s first dengue epidemic occurred in 1925 and the most recent in *** there is still very little known about dengue prevalence,its vector proliferation,and its poverty and equity ***:An exploratory cross-sectional survey was performed from December 2013 to January *** primary healthcare centers in Ouagadougou were selected based on previously reported presence of *** patients consulting with fever or having had fever within the previous week and with a negative rapid diagnostic test(RDT)for malaria were invited to *** data,healthcare use and expenses,mobility,health-related status,and vector control practices were captured using a *** samples of every eligible subject were obtained through finger pricks during the survey for dengue RDT using SD BIOLINE Dengue Duo(NS1Ag and IgG/IgM)®and to obtain blood spots for reverse transcription polymerase chain reaction(RT-PCR)*** a sample of randomly selected yards and those of patients,potential Aedes breeding sites were found and *** were collected and brought to the laboratory to monitor the emergence of adults and identify the ***:Of the 379 subjects,8.7%(33/379)had positive RDTs for *** the 2009 WHO classification,38.3%(145/379)had presumptive,probable,or confirmed dengue,based on either clinical symptoms or laboratory *** 60 samples tested by RT-PCR(33 from the positive tests and 27 from the subsample of negatives),15 were *** serotypes observed were DENV2,DENV3,and *** of dengue infection in 15-to-20-year-olds and persons over 50 years were 4.0(CI 95%:1.0–15.6)and 7.7(CI 95%:1.6–37.1)times higher,respectively,than in children under *** total spending for a dengue episode was 13771 FCFA[1300–67300 FCFA](1$US=478 FCFA).On average,2.6 breeding sites were found per yard.

关键词： Dengue Fever acute febrile non-malaria cases Burkina Faso Aedes Health system Cost Mobility

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