检索结果-南通市图书馆

Percutaneous coronary Intervention in acute coronary syndromes at the Mother-Child University Hospital Luxembourg in Bamako

引用

World Journal of Cardiovascular Diseases 2024年第4期14卷 288-294页

作者： Mamadou Toure Hamma Sankare Baba I. Diarra Mariam Dagnogo Modibo Doumbia Abdoul W. Terra Samba Sidibe Coumba A. Thiam Boubacar Sonfo Boubacar Diarra Asmaou Keita Ousmane Traore Daouda Fofana Almou A. Diall Mady Sow Massama Konate Hamidou O. Ba Ichaka Menta Cardiology Department CHU-Mother Child Bamako Mali Cardiology Department CHU-Gabriel Tour&#233 Bamako Mali Faculty of Medicine University of Sciences Techniques and Technologies of Bamako Bamako Mali Department of Cardiac Surgery Center Andre FESTOC Bamako Mali Cardiology Department CHU-Point G Bamako Mali

Introduction: acute coronary syndromes (ACS) are a diagnostic and therapeutic emergency. Objective: Studying the feasibility, difficulties and results of coronary angioplasty in acute coronary syndromes at the Luxembourg Mother-Child University Hospital in Bamako. Patients and Methods: Cross-sectional, descriptive study with prospective recruitment over 18 months from September 2020 to February 2022. All patients aged at least 18 years old admitted for SCA and having undergone PCI during the study period were included. Result: We collected 249 patients for SCA, of whom 160 underwent angioplasty, either an angioplasty/SCA ratio of 0.64. The average age of the patients was 59.54 ± 11.62 with extremes of 32 and 92 years. The age group of 45 to 65 years was the most representative. The predominance was male, sex ratio of 2.4. The main cardiovascular risk factors were high blood pressure (58.23%) and diabetes (45.78%). Persistent ST-segment elevation on the electrocardiogram was present in 71.48%. The treatment time was more than 12 hours after the first medical contact in 95.5%. The approach was radial in 96.5% of cases. Coronarography was pathological in 91.16% of our patients. The lesions were tri-truncular in 34.13% with the anterior inter ventricular as culprit artery in 72% of cases. The majority of patients (64%) had undergone angioplasty with implantation of an active stent. Angioplasty was performed successfully in 98% and per procedural mortality was 1.87%. Only 6.45% of ACS with ST elevation benefited from primary angioplasty. Conclusion: Percutaneous coronary intervention is performed routinely in our center with satisfactory results. Difficulties exist, related to the diagnostic delay of ACS and the high cost of angioplasty.

关键词： acute coronary syndromes coronary Angiography Angioplasty Mother-Child University Hospital Luxembourg Bamako Mali

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

What Is New in the 2023 European Society of Cardiology Guidelines for the Management of acute coronary syndromes

引用

Cardiology Discovery 2023年第4期3卷 227-231页

作者： Marco Roffi Division of Cardiology University HospitalsGeneva 1211Switzerland

For the first time,European Society of Cardiology(EsC)guidelines have aggregated in 1 single document recommendations for the management of patients with non-ST-segment elevation acute coronary syndromes(NSTE-ACS)and ST-elevation myocardial infarction(STEMI).From a clinical perspective,this is coherent,as the spectrum of clinical presentations in acute coronary syndromes(ACS)may range from new onset or progressive troponin-negative angina to STEMl,cardiogenic shock,or cardiac *** addition,the management pathways of NSTE-ACS and STEMI patients are widely *** with previous editions of the guidelines,the extensive document is improved also from a graphic perspective,containing several appealing and easy-to-understand *** or modified recommendations include,among others,the topics of diagnostic work-up,timing of invasive strategy,revascularization in multi-vessel disease,intravascular imaging,cardiac arrest,cardiogenic shock,and antithrombotic *** the first time in the field of ACS,ESC guidelines have incorporated a section on patient perspectives with dedicated *** of the most relevant changes in recommendations impacting clinical practice are discussed inthis article.

关键词： acute coronary syndromes Guidelines European Society of Cardiology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anemia in patients with high-risk acute coronary syndromes admitted to Intensive Cardiac Care Units

引用

Journal of Geriatric Cardiology 2020年第1期17卷 35-42页

作者： Victoria Lorente Jaime Aboal Cosme Garcia Jordi Sans-Rosello Antonia Sambola Rut Andrea Carlos Tomas Gil Bonet David Vinas Nabil el Ouaddi Santiago Montero Javier Cantalapiedra Margarida Pujol Isabel Hernandez Maria Perez-Rodriguez Isaac Llao Jose C Sanchez-Salado Miquel Gual Albert Ariza-Sole 无 Hospital Universitari de Bellvitge L’Hospitalet de LlobregatBarcelonaSpain Hospital Unversitari Josep Trueta GironaSpain Hospital Universitari Germans Trias i Pujol Badalona BarcelonaSpain Hospital de la Santa Creu i Sant Pau Instituto de Investigación Biomedica IIB Sant PauUniversitat Autonoma de Barcelona(UAB)BarcelonaSpain Hospital Universitari de la Vall d’Hebron BarcelonaSpain Hospital Clinic i Provicial BarcelonaSpain Hospital Arnau de Vilanova LleidaSpain Hospital Joan XXIII TarragonaSpain the Grup de Treball de Cures Agudes Cardiologiques de la Societat Catalana de Cardiologia

Background Little information exists about the role of anemia in patients with acute coronary syndromes(ACS)admitted to Intensive Cardiac Care Units(ICCU).The aim of this study was to assess the prevalence of anemia and its impact on management and outcomes in this clinical *** All consecutive patients admitted to eight different ICCUs with diagnosis of non-ST segment elevation ACS(NSTEACS)were prospectively *** was defined as hemoglobincoronary angiography,but underwent more often intraaortic counterpulsation,non-invasive mechanical ventilation and renal replacement *** ICCU and hospital stay were significantly longer in patients with *** the incidence of mortality(HR=3.36,95%CI:1.43–7.85,P=0.001)and the incidence of mortality/readmission were significantly higher in patients with anemia(HR=2.80,95%CI:2.03–3.86,P=0.001).After adjusting for confounders,the association between anemia and mortality/readmission remained significant(P=0.031).Conclusions Almost one of three NSTEACS patients admitted to ICCU had *** patients underwent coronary *** was independently associated to poorer outcomes at 6 months.

关键词： acute coronary syndromes Anemia Intensive cardiac care units Prognosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of safety and efficacy between fondaparinux and nadroparin in non-ST elevation acute coronary syndromes

引用

Chinese Medical Journal 2011年第6期124卷 879-886页

作者： YAN Hong-bing SONG Li LIU Ran ZHAO Han-jun WANG Shao-pin CHI Yun-peng ZHENG Bin LI Wen-zheng LIU Chen ZHOU Peng Cardiovascular Institute and Fuwai Hospital Peking Union Medical College and Chinese Academy of Medical SciencesBeijing 100037 China Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Background American College of Cardiology/American Heart Association/European Society of Cardiology （ACC/AHA/ESC） guidelines gave fondaparinux a class Ⅰ recommendation for use in patients with non-ST elevation acute coronary syndromes （NSTE-ACS） undergoing invasive or conservative strategy. Nadroparin is one of the common anticoagulants used in NSTE-ACS in China. Accordingly, this study compared the safety and efficacy between fondaparinux and nadroparin in patients with *** In this prospective, randomized, open-label, and single center study, a total of 300 patients with NSTE-ACS were randomized to receive either fondaparinux （group F, n=150, 2.5 mg/d） or nadroparin （group N, n=150, 0.1 ml/10 kgq12 h） for a mean of 4 days. The primary safety endpoint was the incidence of major or minor bleeding at 9 days that was not related to coronary artery bypass grafting （CABG）. The primary efficacy endpoints included death, myocardial infarction, or recurrent ischemia at 9 days. All patients underwent a 180-day *** Baseline characteristics were well matched between the two groups. There was a non-significant 28% relative risk reduction in the primary safety endpoint in group F compared with group N （4.7% vs. 6.7%, HR 0.72, 95% CI0.42-1.65, P=0.38）. The primary efficacy endpoint was 8.0% in group F and 10.0% in group N （HR, 0.82, 95% CI0.54-1.71, P=0.49）. The composite of the safety and efficacy endpoints at 9 days （10.0% vs. 16.0%, HR 0.61, 95% CI0.31-1.10,P=0.10）, 30 days （14.0% vs. 17.9%, HR 0.72, 95% C/0.47-1.16, P=0.21）, or 180 days （18.7% vs. 27.3%, HR0.65, 95% CI0.38-1.11, P=0.11） showed a non-significant trend toward a lower value in group *** Fondaparinux resulted in a nonsignificant risk reduction in patients with NSTE-ACS in both bleeding and ischaemic events during short- and long-term follow-up compared with nadroparin.

关键词： anticoagulants fondaparinux nadroparin acute coronary syndromes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel responsiveness and clinical outcome in patients with acute coronary syndromes undergoing stent-based coronary intervention

引用

Chinese Medical Journal 2013年第6期126卷 1069-1075页

作者： TANG Xiao-fang ZHANG Jia-hui WANG Jing HAN Ya-ling XU Bo QIAO Shu-bin WU Yong-jian CHEN Jue WU Yuan CHEN Ji-lin GAO Run-lin YANG Yue-jin YUAN Jin-qing Department of Cardiology Fu Wai Hospital and Cardiovascular Institute National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China Department of Cardiology Institute of Cardiovascular Research of People's Liberation Army Shenyang Northern Hospital Shenyang Liaoning 110840 China

Background The CYP2C19 G681A single polymorphism has been proven to affect clopidogrel responsiveness. However, the effect of coexisting polymorphisms of other genes has not yet been reported in the Chinese population. This study investigated the effect of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel responsiveness and adverse clinical events in Chinese patients. Methods In 577 Han Chinese patients undergoing stent placement because of acute coronary syndrome had platelet reactivity assessed by thromboelastography, and the CYP2C19 G681A and P2Y12 C34T polymorphisms were detected by the ligase detection reaction. Primary clinical endpoints included cardiovascular death, nonfatal myocardial infarction, target vessel revascularization, and stent thrombosis. The secondary clinical endpoints were thrombolysis in myocardial infarction bleeding. The follow-up period was 12 months. Results Genotyping revealed 194 carriers of the wild type GG genotype of CYP2C19 and the wild type CC genotype of P2Y12 （group 1）, 102 carriers of the wild type GG genotype of CYP2C19 and the mutational T allele of P2Y12 （group 2）, 163 carriers of the mutational A allele of CYP2C19 and the wild type CC genotype of P2Y12 （group 3）, and 118 carriers of the mutational A allele of CYP2C19 and the mutational T allele of P2Y12 （group 4）. Group 4 had the lowest ADP-inhibition （49.74＋32.61） and the highest prevalence of clopidogrel low response （29.7%） of the four groups. The rate of the composite of primary clinical endpoints increased more in group 4 （8.5%） than in the other three groups; the rate of composite primary endpoints in group 2 （2.9%） and group 3 （3.7%） were not significantly different than that of group 1 （1.5%）. Conclusion Coexisting polymorphisms of different genes affected clopidogrel responsiveness and clinical outcome more than single polymorphism in Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention.

关键词： clopidogrel acute coronary syndromes CYP2 C19 P2 Y12 platelet reactivity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

acute coronary syndromes in Semi-Urban African Areas: Clinical Aspects and Management in Ziguinchor (Senegal)

引用

Open Journal of Emergency Medicine 2021年第4期9卷 179-187页

作者： Simon Joël Manga Mame Diarra Mbaye Sidy Lamine Sy Quinta Te Indafa Cardiology Departement Hospital de la Paix Assane Seck University of Ziguinchor Ziguinchor Senegal Cardiologie Departement Fann National University Center Dakar Cheikh Anta Diop University Ziguinchor Senegal

Context and Objectives: acute coronary syndromes (ACS) constitute a major medical emergency. In Senegal, outside the capital Dakar, there is a lack of appropriate care structures. The objective of this work was to stu... 详细信息

Context and Objectives: Acute coronary syndromes (ACS) constitute a major medical emergency. In Senegal, outside the capital Dakar, there is a lack of appropriate care structures. The objective of this work was to study the ACS treatment in the city of Ziguinchor. Methodology: This was a retrospective study of acute coronary syndromes’ cases admitted to the two-level two hospitals in the city of Ziguinchor from January 1, 2016 to December 31, 2019. We included all patients with acute angina pain at rest and/or electrocardiographic changes in at least two contiguous leads. The data were analysed using sphinx V5 software. Results: 57 cases were collected. The average age was 60.1 ± 14.1 years. There was a male predominance with a sex ratio of 3.7. The majority of patients arrived at the hospital by unsafe delivery (70.5%). Symptomatology was dominated by typical angina pain (50.8%). On the electrocardiogram, a majority of acute coronary syndromes with ST segment shift were observed (70.2%). Doppler echocardiography found abnormalities in segmental kinetics in 69.8% of cases. The troponin dosage was performed in 7 patients, i.e. 12.3%. The average time of treatment was 3.4 ± 4.5 days. Medical treatment remained standard and no patient was thrombosed. The average hospitalization period was 5 ± 3.2 days. The hospital lethality was 7.2%. Conclusion: acute coronary syndromes constitute a medical emergency. Dia

关键词： acute coronary syndromes Clinic Management Ziguinchor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

acute coronary syndromes in Elderly: Multicentric Study about 76 Cases in 3 Cardiology Departments in Dakar

引用

World Journal of Cardiovascular Diseases 2021年第12期11卷 610-618页

作者： Momar Dioum Papa Nguirane Ndiaye Cheikh Gaye Yande C. Faye Joseph Salvador Mingou Bouna Diack Dominique I. Bindia Alassane Mbaye Maboury Diao Cardiology Department CHU FANN Dakar Senegal Hoggy Cardiology Department Dakar Senegal Cardiology Department CHU Aristide Le Dantec Dakar Senegal

Background: acute coronary syndromes (ACS) in the elderly are often a problem in their diagnosis and treatment, explaining a high mortality. Our study aimed to evaluate diagnostic, therapeutic and evolutive aspects in... 详细信息

Background: Acute coronary syndromes (ACS) in the elderly are often a problem in their diagnosis and treatment, explaining a high mortality. Our study aimed to evaluate diagnostic, therapeutic and evolutive aspects in 3 cardiology departments of Dakar. Patients and Methods: We conducted a multicentric, retrospective and descriptive study during 2 years from January 1, 2017 to December 31, 2018. All patients older than 75 years admitted for acute coronary syndromes were included. The diagnosis was based on clinical signs with typical electrocardiographic changes and troponin assays. Results: Seventy and six patients (76) were enrolled. The prevalence of ACS in the elderly was 2.5% of all hospitalized patients and 21.8% of all ACS. The average age was 78.76 years. The sex ratio male/female was 1.71. The cardiovascular risk factors were essentially physical inactivity (97%) and hypertension (6.84%). Angina pain was the master symptom, but the pain was atypical in the most cases (52.63%). The second sign was dyspnea (46.05%). The average admission time for patients with STEMI (ST-segment elevation myocardial infarction) was 27 hours. Among these patients, 67% had a STEMI, 24% had NSTEMI (non-ST segment elevation myocardial infarction) and 9% had an unstable angina. Four patients had a thrombolysis with an average time of 5.75 hours. The thrombolysis was not successful for all patients. Eighteen (18) patients had a percutaneous coronary in

关键词： acute coronary syndromes Elderly Dakar Senegal

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anti-inflammatory and profibrinolytic effect of tetramethylpyrazine in acute coronary syndromes

引用

Journal of Geriatric Cardiology 2005年第4期2卷 233-235页

作者： Haiyun WU, Chengyun WEI, Qiang XU, Shiwen WANG Institute of Geriatric Cardiology, General Hospital of Chinese PLA, Beijing Hospital of Intergrated Traditional and Western Medicine attached to Beijing University of TCM, Beijing. Institute of Geriatric Cardiology General Hospital of Chinese PLA Hospital of Inlergrated Traditional and Western Medicine Beijing University of TCM

Background and Objectives Tetramethylpyrazine (TMP) is a herb used widely in Traditional Chinese Medicine (TCM) as an antianginal drug. The exact mechanism whereby TMP treat ischemic heart disease is still not fully understood. The purpose of this study is to examine the anti-inflammatory effect of TMP in patients with acute coronary syndromes (ACS). Methods Thirty-two patients with acute myocardial infarction or unstable angina were randomly assigned to TMP group or control group. All patients received the same standard treatment. Patients in TMP group received TMP 3mg/kg every 12 hours for 5 days. Plasma concentrations of high-sensitivity C-reactive protein (CRP), serum amyloid A (SAA) and plasminogen activator inhibitor-1 (PAI-1) were measured at baseline and after 5 days of therapy. Results Both CRP and SAA concentrations increased significantly in control group (P<0.05) whilst in TMP group, only SAA had a significant increase (P<0.05); the absolute increase of CRP, SAA, and PAI-1 were significantly less in TMP group than in control group (P<0.05). Conclusion TMP has an anti-inflammatory and profibrinolytic effect in patients with ACS. These effects may contribute to the clinical benefits of TMP in ischemic heart disease.

关键词： acute coronary syndromes inflammation tetramethylpyrazine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

acute coronary syndromes: more or less antithrombotic medication for the elderly?

引用

Journal of Geriatric Cardiology 2005年第4期2卷 206-页

作者： Shiwen WANG Haiyun WU Institute of Geriatric Cardiology Chinese PLA General Hospital Beijing 100853 China Institute of Geriatric Cardiology Chinese PLA General Hospital Beijing 100853 China

The treatment of elderly patients with acute coronary syndromes (ACS) remains challenging. About two thirds of patients with ACS and four fifth of patients who died from ACS are older than 65 years.

关键词： more or less antithrombotic medication for the elderly ACS acute coronary syndromes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Relationship between baseline monocyte to high-density lipoprotein cholesterol ratio and acute heart failure in postmenopausal women with acute coronary syndromes

引用

South China Journal of Cardiology 2021年第3期22卷 145-153页

作者： WANG Ying ZHENG Hai-sheng HUANG Zhen-chun ZHENG Xiao-dong Department of Cardiology Shantou Central HospitalShantou 515031GuangdongChina

Monocyte to high-density lipoprotein cholesterol ratio(MHR)becomes a novel cardiovascular prognostic *** retrospective study was performed to investigate the relationship between MHR and acute heart failure(AHF)in postmenopausal women with acute coronary syndromes(ACS).Methods A cohort of 127 postmenopausal women diagnosed with ACS were *** underwent coronary angiography in Shantou Central Hospital(Shantou,China)from December 2014 and July *** patients were assigned to two groups based on the admission MHR:low MHR group(MHR≤0.3677,n=51)and high MHR group(MHR>0.3677,n=76).The relationship between MHR and AHF was assessed by logistic regression *** Left ventricular ejection fraction of the low MHR group(64.2%±8.8%)was higher than that of the high MHR group(57.6%±12.9%)(P=0.002).Fractional shortening of the low MHR group(35.4%±6.4%)was higher than that of the high MHR group(30.6%±8.9%)(P=0.001).Hospitalization days of high MHR group(11.4±6.6 days)was longer than that of low MHR group(8.4±3.5 days)(P=0.006).Incidence of AHF(21%)in the high MHR group was higher than that in the low MHR group(4%)(P=0.008).MHR(OR:25.701,95%CI:3.099-213.143,P=0.003)could be an independent predictor for AHF in postmenopausal women with acute coronary *** The incidence of AHF in high baseline MHR group was higher than that in low baseline MHR *** study demonstrated that high MHR level was a risk factor for AHF in postmenopausal women with ACS.

关键词： monocyte to high-density lipoprotein-cholesterol ratio acute heart failure postmenopausal women acute coronary syndromes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：