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Pulmonary Embolism in Patients with acute Exacerbation of Chronic Obstructive Pulmonary Disease

Chinese Medical Journal 2018年第14期131卷 1732-1737页

作者： Yao-Qian Cao Li-Xia Dong Jie Cao Department of Respiratory General Hospital Tianjin Medical University Tianjin 300052 China

Objective： In most cotintries, nearly 6% of the adults are suffering from chronic obstructive pulmonary disease （COPD）. which puts a huge economic burden on the society. Moreover, COPD has been considered as an independent risk factor for pulmonary embolism （PE）. In this review, we summarized the existing evidence that demonstrates the associations between COPD exacerbation and PE from various aspects, including epidemiology, pathophysiological changes, risk factors, clinical features, management, and prognosis. Data Sources： We searched the terms ＂chronic obstructive pulmonary disease,＂＂＇pulmonary embolism,＂＂exacerbations,＂ and ＂＇thromboembolic＂ in PubMed database and collected the results up to April 2018. The language was limited to English. Study Selection： We thoroughly examined the titles and abstracts of all studies that met our search strategy. The data from prospective studies, meta-analyses, retrospective studies, and recent reviews were selected for preparing this review. Results： The prevalence of PE in patients with COPD exacerbation varied a lot among different studies, mainly due to the variations in race, sample size, study design, research setting, and enrollment criteria. Overall, whites and African Americans showed significantly higher prevalence of PE than Asian people, and the hospitalized patients showed higher prevalence of PE compared to those who were evaluated in emergency department. PE is easily overlooked in patients with COPD exacerbation due to the similar clinical symptoms. However, several factors have been identified to contribute to the increased risk of PE during COPD exacerbation. Obesity and lower limb asymmetry were described as independent predictors for PE. Moreover, due to the high risk of PE, thromboprophylaxis has been used as an important treatment for hospitalized patients with COPD exacerbation. Conclusions： According to the previous studies, COPD patients with PE experienced an increased risk of death and prolonged length of hospital stay. Therefore, the thromboem

关键词： acute exacerbations Chronic Obstructive Pulmonary Disease Pulmonary Embolism

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Study on the construction of symptom association model based on association rules

Study on the construction of symptom association model based...

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第36届中国控制会议

作者： Zhiwan Wang Jiansheng Li Chuxiang Chen Liang Zhang Xiang Wang Xiaobo Yang Haixia Li Ling Li The First Affiliated Hospital of Henan University of TCM Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province Zhengzhou Institute of Information Science and Technology Zhengzhou University of Aeronautics

ISBN: (纸本)9781538629185

With complex pathogenesis,Chronic Obstructive Pulmonary Disease（COPD） is difficult to treat.Traditional Chinese Medicine（TCM） showed obvious effect in treating COPD.However,invaluable TCM experience lacks of systematic summarization and study.Association rule is used to discover the relationships among data items in a large amount of data.Because of clear and useful results,association rule is widely used in study of TCM syndrome.In this paper,association model of symptom of phlegm-heat obstructing lung in acute exacerbation COPD is constructed.

关键词： Association rules Chronic Obstructive Pulmonary Disease（COPD） acute exacerbations the syndrome of phlegm-heat obstructing lung symptoms

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