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检索条件"主题词=Acridine Topoisomerases Tyrosine kinases Antitumor DNA-binding"
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Novel synthetic 9-benzyloxyacridine analogue as both tyrosine kinase and topoisomerase I inhibitor
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Chinese Chemical Letters 2013年 第8期24卷 677-680页
作者: Xu-Liang Lang Qin-Sheng Sun Yu-Zong Chen Lu-Lu Li Chun-Yan Tan Hong-Xia Liu Chun-Mei Gao Yu-Yang Jiang Department of Chemistry Tsinghua University The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology Bioinformatics and Drug Design Group.Department of Pharmacy Centre for Computational Science and Engineering Shenzhen Anti-Tumor Drug Development Engineering Laboratory The Graduate School at ShenzhenTsinghua University School of Medicine Tsinghua University
Multi-target agents against tyrosine kinases and topoisomerases are potentially useful for the effective treatment of *** of new multi-target scaffolds are important for developing such agents. A series of five novel ... 详细信息
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