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Co-localization of two-color rAAV2-retro confirms the dispersion characteristics of efferent projections of mitral cells in mouse accessory olfactory bulb

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Zoological Research 2020年第2期41卷 148-156页

作者： Ning Zheng Zhi-Zhong Wang Song-Wei Wang Fang-Jia Yang Xu-Tao Zhu Chen Lu Anne Manyande Xiao-Ping Rao Fu-Qiang Xu Center of Brain Science State Key Laboratory of Magnetic Resonance and Atomic and Molecular PhysicsNational Center for Magnetic Resonance in WuhanKey Laboratory of Magnetic Resonance in Biological SystemsWuhan Institute of Physics and MathematicsInnovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhanHubei 430071China University of the Chinese Academy of Sciences Beijing 100049China Department of Automation School of Electrical EngineeringZhengzhou UniversityZhengzhouHenan 450001China School of Life Science Wuhan UniversityWuhanHubei 430072China School of Human and Social Sciences University of West LondonMiddlesex TW89GAUK Divisions of Biomedical Photonics Wuhan National Laboratory for OptoelectronicsWuhanHubei 430074China

The accessory olfactory bulb(AOB), located at the posterior dorsal aspect of the main olfactory bulb(MOB), is the first brain relay of the accessory olfactory system(AOS), which can parallelly detect and process volatile and nonvolatile social chemosignals and mediate different sexual and social behaviors with the main olfactory system(MOS). However, due to its anatomical location and absence of specific markers, there is a lack of research on the internal and external neural circuits of the AOB. This issue was addressed by singlecolor labeling and fluorescent double labeling using retrograde rAAVs injected into the bed nucleus of the stria terminalis(BST), anterior cortical amygdalar area(ACo), medial amygdaloid nucleus(MeA), and posteromedial cortical amygdaloid area(PMCo) in mice. We demonstrated the effectiveness of this AOB projection neuron labeling method and showed that the mitral cells of the AOB exhibited efferent projection dispersion characteristics similar to those of the MOB. Moreover, there were significant differences in the number of neurons projected to different brain regions, which indicated that each mitral cell in the AOB could project to a different number of neurons in different cortices. These results provide a circuitry basis to help understand the mechanism by which pheromone information is encoded and decoded in the AOS.

关键词： accessory olfactory bulb Efferent projections Retrograde rAAVs Projection neuron labeling Dispersion characteristics Circuitry basis

Is an accessory nipple associated with an intrapancreatic accessory spleen?

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Hepatobiliary & Pancreatic Diseases International 2019年第6期18卷 596-597页

作者： Hai-Tao Huang Qi Ling Department of Surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Intrapancreatic accessory spleen(IPAS)is a rare differential diagnosis of a solitary hypervascular *** is not uncommon to misdiagnose IPAS as pancreatic tumors since no specific imaging has been developed for the differential *** described a rare case of a male patient with a unilateral accessory nipple and a solitary hypervascular lesion in the *** patient underwent a distal pancreaticosplenectomy,and IPAS was finally diagnosed.

关键词： spleen diagnosis accessory

Clinical implications of accessory pancreatic duct

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World Journal of Gastroenterology 2010年第36期16卷 4499-4503页

作者： Terumi Kamisawa Kensuke Takuma Taku Tabata Naoto Egawa Department of Internal Medicine Tokyo Metropolitan Komagome Hospital3-18-22 HonkomagomeBunkyo-kuTokyo 113-8677Japan

The accessory pancreatic duct (APD) is the main drainage duct of the dorsal pancreatic bud in the embryo,entering the duodenum at the minor duodenal papilla (MIP).With the growth,the duct of the dorsal bud undergoes varying degrees of atrophy at the duodenal *** of the APD in 291 control cases was 43% as determined by dye-injection endoscopic retrograde *** of the APD in 46 patients with acute pancreatitis was only 17%,which was significantly lower than in control cases (P < 0.01).The terminal shape of the APD was correlated with APD *** on the data about correlation between the terminal shape of the APD and its patency,the estimated APD patency in 167 patients with acute pancreatitis was 21%,which was signif icantly lower than in control cases (P < 0.01).A patent APD may function as a second drainage system for the main pancreatic duct to reduce the pressure in the main pancreatic duct and prevent acute *** f indings of 91 patients with pancreaticobiliary maljunction (PBM) were divided into a normal duct group (80 patients) and a dorsal pancreatic duct (DPD) dominant group (11 patients).While 48 patients (60%) with biliary carcinoma (gallbladder carcinoma,n=42;bile duct carcinoma,n=6) were identified in PBM with a normal pancreatic duct system,only two cases of gallbladder carcinoma (18%) occurred in DPD-dominant patients (P < 0.05).Concentration of amylase in the bile of DPD dominance was signifi cantly lower than that of normal pancreatic duct system (75 403.5 ± 82 015.4 IU/L vs 278 157.0 ± 207 395.0 IU/L,P < 0.05).In PBM with DPD dominance,most pancreatic juice in the upper DPD is drained into the duodenum via the MIP,and reflux of pancreatic juice to the biliary tract might be reduced,resulting in less frequency of associated biliary carcinoma.

关键词： accessory pancreatic duct Minor duodenal papilla Pancreas divisum Main pancreatic duct Acute pancreatitis Pancreaticobiliary maljunction

Differentiation and accumulation of fluids in A-type granites: Evidence from accessory mineral study

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Chinese Science Bulletin 2000年第17期45卷 1609-1613页

作者： WANG Rucheng ZHAO Guangtao WANG Dezi LU Jianjun XU Shijin Department of Earth Sciences and State Key Laboratory for Mineral Deposits Research Nanjing UniversityNanjing 210093China Department of Ocean Geology Qingdao Ocean UniversityQingdao 266003China

The Laoshan A-type granite is a highly evolved granite body. The study on accessoryminerals indicates that there exist differentiation and accumulation of fluids during the late stage of evolution of the granite. The released fluids are rich in rare-earth elements (REE), high-field-strength elements (HFSE, such as Nb, Ta, Zr, Hf, Th, U, and Y) and volatiles (F, P, CO2, etc.). Owing to the presence of fluid, accessory mineral assemblages have changed during the evolution of A-type granite, and are especially characterized by large amounts of independent REE-Nb-Y-Th minerals present in the late facies. Late-accumulation of fluids may be of the general feature of A-type granites, at least of highly evolved ones.

关键词： accessory minerals fluid A-type granite Laoshan.

Gastric duplication cyst communicating to accessory pancreatic lobe: A case report and review of the literature

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World Journal of Clinical Cases 2018年第16期6卷 1182-1188页

作者： Michael Rousek David Kachlik Andrej Nikov Jirina Pintova Miroslav Ryska Department of Surgery 2~(nd) Faculty of Medicine Charles University and Central Military Hospital Department of Anatomy 2~(nd) Faculty of Medicine Charles University Department of gastroenterology Jablonec nad Nisou Hospital

Background The combination of a gastric duplication cyst and duplicated part of the pancreas is an extremely rare developmental defect. The incidence in the population, or the clinical impact thereof, has not been uncovered. Symptoms are unspecific. Surgery is the treatment of choice. Timely diagnostics are of utmost importance, albeit they might be challenging at times. Being so rare, case reports are currently the only relevant source of information about the condition. Therefore each published finding is of a clinical *** summary Our work describes the case of a 22 year-old patient, who developed idiopathic acute pancreatitis. A computed tomography scan discovered liquid collection between the antrum of the stomach and the head of the pancreas. Initially, the collection was thought to be a pancreatic pseudocyst. Endoscopic ultrasoundguided transgastric drainage showed to have only a temporary therapeutic effect. Magnetic resonance cholangiopancreatography showed an accessory pancreatic lobe with a separate duct system. The accessory pancreatic lobe exited the body of the pancreas andwas in contact with the cystic collection. The patient was indicated for surgical resection. Within the surgery, an en bloc resection of the accessory pancreatic lobe was performed with the antrum of the stomach containing the gastric duplication cyst. No complications were observed in the surgery or thereafter. In the five months follow-up period, the patient was completely symptom free. Histopathological findings confirmed the gastric duplication cyst communicating to accessory pancreatic *** This developmental defect is extremely rare. It can cause recurrent acute pancreatitis. Diagnostics are challenging. Surgery is treatment of choice.

关键词： Pancreatic resection accessory pancreatic lobe Acute pancreatitis Developmental defect Gastric duplication cyst Case report

The manifest right accessory pathway led to reversible left ventricular dyssynchrony and dysfunction

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上海医学 2007年第S1期30卷 224-225页

作者： SHAN Qijun, JIN Yu, CAO K ejiang From Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

We report observations in a 7 year old girl with manifest right accessory pathway (AP) and depressed cardiac function. Her Echocardiogram showed LV dilatation with asynchronous ventricular wall motion and LVEF reduction. The electrophysiological study demonstrated a para-his AP. She underwent successfully ablation and without any complications. The Echo validated that asynchronous ventricular wall motion disappeared after ablation. Her cardiac size and function was normal after follow up of three month. Our findings suggested that manifest AP leading to asynchronous ventricular motion was a possible cause of left ventricular dilation and dysfunction. Catheter ablation could reverse cardiac remodeling in such patient. Case report A seven year old girl was referred to our hospital for fainting episode in last six month. To exclude cephalic syncope, she underwent electroencephalogram, the result was negative. The electrocardiogram (ECG) showed right AP. An apparent delta wave looked like LBBB pattern with short PR interval (80ms) and long QRS duration (180ms) (figure 1 left panel). Echocardiogram (Echo) revealed left ventricle dilatation and left ventricular ejection fraction reduction (LVDd=52mm, LVEF=46%). Asynchronous ventriclular wall motion and moderate mitral valve regurgitation also observed on Tissue Doppler Imaging (TDI). She underwent electrophysiology study (EPS) and ablation procedure on the 5th hospital day. The intracardiac electrogram showed a para-His AP with antegrade conduction. The orthodromic SVT (201 bpm) was induce right ventricular apex programmed stimulation. During SVT episode, her symptom was similar to spontaneous one. After successful ablation, delta wave on ECG disappeared and SVT can not be induced with or without isoproterenol. Normal atrial-ventricular conduction was kept without any complications. Prior to discharge, Echo showed the LVEF slightly improved and TDI indicated that asynchronous ventricular wall motion disappeared. She was d

关键词： manifest accessory dilatation ejection ablation remodeling medication reversible conduction asynchro

STUDY OF PHRENIC OR accessory NERVE NEUROTIZATION FOR TREATMENT OF ROOT AVULSION OF THE BRACHIAL PLEXUS IN RATS．

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中华创伤杂志 1994年第3期 56-60页

作者：马建军顾玉东陈德松左焕琛陈丽莲

Ｐｈｒｅｎｉｃｎｅｒｖｅｏｒａｃｃｅｓｏｒｙｎｅｒｖｅｉｍｐｌａｎｔａｔｉｏｎｗｉｔｈａｇｒａｆｔｏｆａｓｅｇｍｅｎｔｏｆｔｈｅｓｕｒａｌｎｅｒｖｅｔｏｔｈｅｂｉ┐ｃｅｐｓｍｕｓｃｌｅｗａｓｅｍｐｌｏｙｅｄｆｏｒｔｈ... 详细信息

Ｐｈｒｅｎｉｃｎｅｒｖｅｏｒａｃｃｅｓｏｒｙｎｅｒｖｅｉｍｐｌａｎｔａｔｉｏｎｗｉｔｈａｇｒａｆｔｏｆａｓｅｇｍｅｎｔｏｆｔｈｅｓｕｒａｌｎｅｒｖｅｔｏｔｈｅｂｉ┐ｃｅｐｓｍｕｓｃｌｅｗａｓｅｍｐｌｏｙｅｄｆｏｒｔｈｅｔｒｅａｔｍｅｎｔｏｆｒｏｏｔａ...

关键词： FOR BRACHIAL accessory IN NERVE NEUROTIZATION OF PHRENIC PLEXUS RATS

accessory Nerve Schwannoma Extending to the Foramen Magnum and Mimicking Glossopharyngeal Nerve Tumor—A Case and Review of Surgical Techniques

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World Journal of Neuroscience 2017年第3期7卷 233-243页

作者： Seidu A. Richard Zhi Gang Lan Yuekang Zhang Chao You Department of Neurosurgery Post-Graduate Training Centre West China Hospital Sichuan University Chengdu China Department of Immunology Jiangsu University Zhenjiang China

Background: Intracranial schwannomas of the accessory nerve are very rare lesions. They are categorised according to their locations into either intrajugular or intracistemal schwannomas although most of them are intrajugular. The intrajugular type constitutes about 2% to 4% of all intracranial schwannomas described in literature. Aim: It’s very unusual for an accessory nerve to mimic glossopharyngeal nerve looking at the anatomical location of the accessory nerve. Although many authors have written on accessory nerve, none have described this unusual presentation. We present a case, management as well as review on the classification and appropriate surgical techniques we could have use to access the tumor in our patient since the choice of a particular surgical approach is based on the nature of tumor, location as well as it extension into other adjacent structures. Case Presentation: We present a case of 52-year-old woman with very unusual accessory nerve schwannoma which mimics the clinical presentation of glossopharyngeal nerve tumor. The main symptom in our case is six (6) months history of deviation of the tongue to right side with dizziness and change of voice. Conclusion: The unusual presentation in our case could be due to massive compression of glossopharyngeal nerve by the growing accessory nerve schwannoma since most lower cranial nerve schwannomas at this location will almost always course compressive symptoms.

关键词： Schwannoma accessory Nerve Glossopharyngeal Nerve Suprajugular Retrosigmoid Translabyrinthine

accessory Leaflet of Tricuspid Valve Masquerading as Infective Endocarditis Preoperatively and Causing RVOT Obstruction Postoperatively

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World Journal of Cardiovascular Surgery 2015年第2期5卷 7-10页

作者： Nishith Bhargava Saket Agrawal Deepak K. Tempe Deepak K. Satsangi Department of Cardiothoracic and Vascular Surgery (CTVS) GB Pant Hospital (GBPH) New Delhi India GB Pant and GNEC Hospitals New Delhi India

accessory tricuspid valve tissue is a rare congenital anomaly. We report a case where preoperative echocardiogram was suggestive of infective vegetations over the tricuspid valve but intra-operatively it was found to ... 详细信息

关键词： accessory Tricuspid Valve Endocardial Vegetations Echocardiogram