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Systematic review of absorbable vs non-absorbable sutures used for the closure of surgical incisions

World Journal of Gastrointestinal Surgery 2014年第12期6卷 241-247页

作者： Muhammad S Sajid Malcolm R Mc Fall Pauline A Whitehouse Parv S Sains Western Sussex Hospitals NHS Trust Washington Suite North Wing Worthing Hospital BN11 2DH West Sussex United Kingdom Department of General Endoscopic and Laparoscopic Colorectal Surgery Worthing Hospital Worthing BN11 2DH West Sussex United Kingdom

AIM: To report a systematic review of published randomized controlled trials(RCTs) investigating the role of absorbable suture(AS) against non-AS(NAS) used for the closure of surgical ***: RCTs investigating the use of AS vs NAS for the closure of surgical incisions were statistically analysed based upon the principles of meta-analysis and the summated outcomes were represented as ***: The systematic search of medical literature yielded 10 RCTs on 1354 patients. Prevalence of wound infection(OR = 0.97; 95%CI: 0.56, 1.69; Z = 0.11; P = 0.92) and operative morbidity(P = 0.45) was comparable in both groups. Nonetheless, the use of AS lead to lower risk of wound break-down(OR = 0.12; 95%CI: 0.04, 0.39; Z = 3.52; P < 0.0004).CONCLUSION: This meta-analysis of 10 RCTs demonstrates that the use of AS is similar to NAS for skin closure for surgical site infection and other operative morbidities. AS do not increase the risk of skin wound dehiscence,rather lead to a reduced risk of wound dehiscence compared to NAS.

关键词： Skin closure Surgical site infection Wound dehiscence absorbable sutures Non-absorbable suture

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Comperative analysis of unilateral cleft lip closure using absorbable and nonabsorbable sutures: a randomised clinical study

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Plastic and Aesthetic Research 2014年第1期1卷 54-57页

作者： Abhay Nilkanth Datarkar Darshan Rewanwar Anshul Rai Department of Cleft and Craniofacial Surgery Child Hospital and Research InstituteNagpur 440013MaharashtraIndia

Aim:Patients with cleft lip usually undergo multiple procedures that require hospitalization resulting in emotional stress to their family *** patients often require sedation or general anesthesia(GA)for suture removal on a sensitive area to prevent disruption of the *** this study,we compared absorbable and nonabsorbable sutures for primary cleft lip ***:Patients with cleft lip who presented to Smile Train Unit,Child Hospital and Research Institute,Nagpur,India,were randomly assigned to two groups and underwent surgical repair using either Vicryl Rapid suture(Group 1)or Prolene suture(Group 2).Patients were followed up at 1 month,6 months,and 1 *** of the patients were obtained at these visits and rated using a validated 100-mm cosmesis visual analogue scale(VAS)by three people(social worker,surgeon,and patient’s mother).A VAS score of 15 mm or greater was considered as clinically important ***:A total of 60 patients were enrolled in this study,and they were equally divided into two *** was no difference in age,race,sex,wound length,number of sutures,and layered repair rates between the *** average age of the patient was 3 *** was no significant difference in the rates of infection which was 6%in this study,wound dehiscence,and hypertrophic scar *** significant difference was found in cosmetic outcome in both the mean VAS score of 90.3 in Group 1 and 91.7 in Group ***:absorbable sutures are a viable alternative to nonabsorbable sutures in the repair of primary cleft lip *** prefer absorbable sutures because they do not require removal under GA or sedation.

关键词： absorbable sutures primary cleft lip visual analogue scale

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