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Histopathological Observation of Cynoglossus semilaevis Günther with abdominal dropsy in Industrial Aquaculture

Agricultural Biotechnology 2016年第1期5卷 37-39页

作者： Guangping GAO Guisheng GAO Yanying ZHANG Zhixin JI Qinghui JIA Ting SU Qiumei SHI Hong-shengHAN Qingchun Song Jianxin ZHU Key Laboratory of Preventive Veterinary Medicine of Hebei Province/Hebei Normal University of Science and Technology Qinhuangdao 066600China Qinhuangdao Liangfeng Marine Ecological Polytron Technologies Inc. Qinhuangdao 066600China Hebei Haohai Biological Technology Co. Ltd.Qin-huangdao 066004China Yellow Sea Fisheries Research Institute Chinese Academy of Fisheries SciencesQingdao 266071China

[ Objective] This study aimed to investigate and analyze the histopathological changes in various tissues and organs of Cynoglossus semilaevis Gunther with abdominal dropsy. [ Method] By HE staining, pathological tissues of main organs of C. semilaevis Giinther with abdominal dropsy were observed. [ Result] According to the results of histopathological observation, C. semilaevis Gilnther with abdominal dropsy exhibited a large amount of ascites in the abdominal cavity; small intestinal mucosal epithelial cells were denatured and necrotic, and shed into the enteric cavity, with submucosal vascular congestion; the liver and pancreas tissues were denatured and necrotic, and the morphology of most liver cells disappeared. However, there was no remarkable pathological change in the heart, spleen and other organs. [ Conclusion] C. semilaevis Gtinther with abdominal dropsy exhibited serious pathological and histochemical lesions in the small intestine, liver and pancreas, causing metabolic disorders.

关键词： Half-smooth tongue sole (Cynoglossus semilaevis Giinther) abdominal dropsy Histopathological observation

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Glucocorticoids combined with tofacitinib in the treatment of Castleman’s disease:A case report

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World Journal of Clinical Cases 2022年第29期10卷 10794-10802页

作者： Xiao-Rui Liu Mei Tian Department of Rheumatology and Immunology Affiliated Hospital of Zunyi Medical UniversityZunyi 563003Guizhou ProvinceChina

BACKGROUND Castleman’s disease(CD),also known as vascular follicular lymphadenopathy is a rare proliferative disease of lymphoid tissue of unknown etiology that is clinically classified as unicentric CD(UCD) or multicentric CD(MCD) depending on lymph node *** present,idiopathic MCD(iMCD) is treated with interleukin-6 inhibitors,but some patients have poor clinical *** paper reports on a case of iMCD that achieved a good therapeutic effect after treatment with glucocorticoids combined with *** relevant data are summarized and reported *** SUMMARY This paper reports on a case of MCD in a 49-year-old female with persistent peritoneal effusion as the first manifestation and combined with multiple *** node biopsy showed Castleman’s disease-like *** ascites subsided after treatment with glucocorticoids and tofacitinib,indicating that the treatment was *** The combination of glucocorticoids with tofacitinib is an effective regimen for the treatment of CD.

关键词： Castleman’s disease Multicentric Castleman’s disease Idiopathic multicentric Castleman’s disease abdominal dropsy Tofacitinib Glucocorticoids Case report

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