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A RANDOMIZED TRIAL OF ELECTROACUPUNCTURE FOR FATIGUE, SLEEP, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia

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Journal of Integrative Medicine 2014年第3期 296-297页

作者： Jun Mao Perelman School of Medicine at University of Pennsylvania

Background: While fatigue, sleep disturbance, depression and anxiety are associated with pain in breast cancer patients, it is unknown if acupuncture can decrease these co-morbid symptoms in cancer patients with *** study aimed at evaluating the effects of electroacupuncture(EA) on fatigue, sleep and psychological distress in breast cancer survivors who experience joint pain related to aromatase inhibitors(AIs).Methods: We performed a randomized controlled trial of an eight-week EA as compared to waitlist control(WLC) and sham acupuncture(SA) in postmenopausal women with breast cancer who self-reported joint pain attributable to *** performed 10 EA/SA treatments over eight weeks using a manual protocol with 2 Hz electro-stimulation delivered by a TENS *** administered SA using Streitberger(nonpenetrating) needles at non-acupuncture points without ***, sleep disturbance, anxiety and depression were measured by the Brief Fatigue Inventory(BFI), Pittsburgh Sleep Quality Index(PSQI), and Hospital Anxiety and Depression Scale(HADS).The effects of EA and SA *** on these outcomes were evaluated using mixed-effects ***: Of the 67 randomly assigned patients, baseline paininterference was associated with fatigue(Pearson correlation coefficient r=0.75, Prelated arthralgia, EA produced significant improvement in fatigue, anxiety and depression, while SA improved only *** findings provide initial evidence to suggest that EA may reduce pain-related symptom clusters in breast can

关键词： WLC SLEEP and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia SA A RANDOMIZED TRIAL OF ELECTROACUPUNCTURE FOR FATIGUE

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