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All CABG Patients Who Have No Contraindications: Do They Get Perioperative Beta Blockers?

International Journal of Clinical Medicine 2019年第9期10卷 421-427页

作者： Mohammad Miah Mauin Uddin Syed Al Nahian Khalid Zahir Mostafa Mehanna Ahmed Ashoub Cardiac Surgery Queen Elizabeth Hospital Birmingham UK Cardiothoracic Surgery New Cross Hospital Wolverhampton UK Cardiothoracic Surgery Liverpool Heart and Chest Hospital Liverpool UK Cardiothoracic Anaesthesia and Critical Care New Cross Hospital Wolverhampton UK

New-onset postoperative atrial fibrillation (POaf) following Coronary artery bypass graft (CABG) surgery has been described in up to 15% to 40% of patients in the initial postoperative period. POaf is related with higher mortality, increased hospital resource utilization, postoperative extra ITU hours and hospital days, consequently increasing hospital-related budgets. Beta blocker administration decreases the rate of POaf from 30% - 40% to 12% - 16% after CABG. According to the EACTS (European Association of Cardiothoracic Surgery) guideline December 2006, β-Blockers should routinely be used as the first choice for the prophylaxis of atrial fibrillation (af) in all patients undergoing cardiac surgery, if not contraindicated (IB). To compare the contemporary practice with the recommended standard retrospective data of consecutive 400 patients treated with isolated CABG between July 2015 and June 2017 were collected. Those patients who received β-blockers on the day of surgery or the following morning (Continued and Restarted on 1st POD) met the standard guidelines. Thus, according to the data (12% + 20%) 32% of the patients met the standard. To compare the rate of Postoperative atrial fibrillation, we divided the patients into two groups. Group A, who followed the guideline (128 patients) and Group B, who resumed β-Blockers 48 hours onwards (272 Patients). In group A, only 8 patients developed postoperative af whereas in group B 88 patients developed postoperative af which is also statistically significant (P β-blockers use at perioperative period.

关键词： CABG-Coronary Artery Bypass Graft β-Blockers af-atrial Fibrillation POaf-Postoperative atrial Fibrillation

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