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Mutations of TP53 Gene and Oxidative Stress in Alzheimer’s Disease Patients
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Advances in Alzheimer's Disease 2014年 第1期3卷 24-32页
作者: Jolanta Dorszewska Agata Rozycka Anna Oczkowska Jolanta Florczak-Wyspianska Michal Prendecki Mateusz Dezor Izabela Postrach Pawel P.Jagodzinski Wojciech Kozubski Laboratory of Neurobiology Department of NeurologyPoznan University of Medical SciencesPoznanPoland Department of Biochemistry and Molecular Biology Poznan University of Medical SciencesPoznanPoland Chair and Department of Neurology Poznan University of Medical Sciences10Fredry Str.61-701 PoznanPoland
Alzheimer’s disease (AD) leads to the generation of β-amyloid (Aβ), which may damage DNA and thus lead to apoptosis induction by the p53 pathway. Dysfunction of the p53 protein may then be connected with the develo... 详细信息
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