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Implementation of tactical maneuvers with maneuver libraries

Chinese Journal of Aeronautics 2020年第1期33卷 255-270页

作者： Do hyeon LEE Chang-Joo KIM Sung wook HUR Seong han LEE School of Aerospace Information Engineering Konkuk UniversitySeoul 05029Republic of Korea

this study creates and combines the general maneuver libraries for fixed-wing aircraft to implement tactical ***,the generalized maneuver libraries are established by analyzing the characteristics of tactical maneuvers required in *** 7th order polynomial is applied to both the creation of the maneuver libraries and the generation of the trajectories or flight paths for modal *** track the desired trajectory,we design the Attitude Command Attitude Hold(ACAH)system and the Rate Command Rate Hold(RCRH)system using Model Following Controller(MFC).Moreover,the Line-of-Sight(LOS)guidance law is *** particular,the CONDUIT~?is employed to optimize the gains so that the control systems meet the aircraft Handling Qualities(HQ)***,flight simulations are performed for the longitudinal loop,immelmann-turn,and climb-slalom-descent maneuvers to verify that tactical aggressive maneuvers are realizable via the combination of maneuver *** study can contribute to the development of flight techniques for aircraft tactical maneuvers and to the revision of air force operational manuals.

关键词： 7th order polynomial Attitude command attitude hold system Handling qualities Maneuver libraries Rate command rate hold system Tactical maneuvers

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Efficacy of Postoperative Adjuvant Chemotherapy According to Prognostic Factor in Patients with Stage III Colon Cancer

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Journal of Cancer therapy 2014年第8期5卷 806-816页

作者： Kiichi Sugimoto Kazuhiro Sakamoto Yuichi Tomiki Michitoshi Goto Yutaka Kojima Hiromitsu Komiyama Makoto Takahashi Shun Ishiyama Koichiro Niwa Haruna Okubo Department of Coloproctological Surgery Juntendo University Faculty of Medicine Tokyo Japan

Background: We retrospectively identified prognostic factors in patients with Stage III colon cancer and considered the effectiveness of postoperative adjuvant chemotherapy based on these prognostic factors. Methods: Two hundred and thirty four patients with lymph node metastases who underwent curative surgery for colon cancer between 1999 and 2005 were enrolled in the present study. Firstly, clinicopathological factors and survival data, were analyzed to determine prognostic factors related to cancer-specific survival. Secondly, we examined the effectiveness of postoperative adjuvant chemotherapy based upon these prognostic factors. Results: the multivariate analysis revealed that differentiation (P = 0.03, Hazard ratio = 2.50), lymphatic invasion (P = 0.02, Hazard ratio = 3.23) and the TNM classification, 7th?edition (P = 0.04, Hazard ratio = 1.94) were found to be significant independent prognostic factors. Among the patients classified as TNM IIIA, the recurrence-free survival rates were extremely good. Among the patients classified as IIIB and IIIC, there was no significant difference between the patients with and without postoperative adjuvant chemotherapy. Conclusion: the present study suggests that the patients with Stage IIIA colon cancer may not require postoperative adjuvant chemotherapy. the addition of oxaliplatin to 5-FU should be considered for the patients with Stage IIIB and IIIC colon cancer, for whom the prognoses are far from satisfactory.

关键词： Colorectal Cancer Postoperative Adjuvant Chemotherapy Prognostic Factor Stage III Colon Cancer TNM Classification 7th Edition

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