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世界核心医学期刊文摘（眼科学分册） 2005年第10期1卷 46-46页

作者： Boji L. Ermacora R. PoliS. 王文军 Department of Ophthalmology Clinical Hospital of Split Spinieva 1 21000 Split Croatia

Background: The purpose of this study was to investigate the frequency of asym ptomatic left ventricular dysfunction in patients with pseudoexfoliation syndrom e. Methods: Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9±5. 6 years, and 24 healthy volunteers aged 63.9±6.5 years. Left ventricular (LV) s ystolic contraction and ejection were assessed by LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling parameters tested were: early f ast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velo city time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE/VTIA), pre ssure at the end of filling (LVEDP)-and a pulmonary capillary wedge pressure (P CWP). Results: Systolic parameters EF and FS, diastolic filling parameters such as A, LVEDP and PCWP were not significantly different between patients with pseu doexfoliation syndrome and controls (P > 0.05). A significant difference (P < 0. 05) was found with regard to the diastolic filling parameters: E (61.6±15.1 vs 83.7±21.4), ratio E/A (0.8±0.1 vs 1.1±0.2), VTIE (8.6±1.8 vs 9.8±1.9), VTIA (10.3±2.4 vs 7.8±1.6)-and ratio VTIA/VTIE (1.2±0.2 vs 0.8±0.2). Conclusion : Our study suggests the possibility of an association between patientswith pseu doexfoliation syndrome and a discrete asymptomatic myocardial diastolic dysfunct ion.

关键词：鳞片样脱皮心肌功能障碍无症状舒张期射血分数左心室健康受试者超声心动描记术性功能障碍心肌舒张

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相对前部小眼症的白内障手术

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世界核心医学期刊文摘（眼科学分册） 2005年第12期1卷 59-60页

作者： Nihalani B.R Jani U.D Vasavada A.R Auffarth G.U 王永强 Iladevi Cataract and IOL Research Centre Gurukul Road Memnagar Ahmedabad 380 052 India.Dr

Purpose: To determine the prevalence of relative anterior microphthalmos (RAM) and evaluate intraoperative performance and surgical outcome in eyes with RAM undergoing cataract surgery. Design: Nested case-control series. Participants: One thousand four hundred consecutive patients undergoing cataract surgery were evaluated to determine the prevalence of RAM. Relative anterior microphthalmos is defined as horizontal corneal diameter (HCD) ≤ 11 mm, anterior chamber depth (ACD) ≤ 2.2 mm, and axial length (AL)>20 mm, with no other morphologic malformation. Methods: Patients were examined preoperatively for HCD, ACD, and AL. Horizontal corneal diameter was measured with calipers. Anterior chamber depth and AL were measured with immersion shell with water. Associated ocular pathologic conditionswere recorded. Two control groupswere identified. Group I (normal eyes; n=84) had HCD >11 mm, ACD >2.2 mm, and AL >20 mm. Group II (eyes with small corneal diameter; n=84) had HCD ≤ 11 mm, ACD >2.2 mm, and AL >20 mm. Main Outcome Measures: Patients with RAM and controls were evaluated for intraoperative performance and postoperative outcome. The 2- tailed Fisher exact test was applied to compare the performance of RAM with each of the control groups. The odds ratio (OR) with 95% confidence intervals (95% CI) was determined. Results: The prevalence of RAM was 6% (84 of 1400 eyes; 95% CI, 0.048- 0.074). Relative anterior microphthalmos was associated with the presence of small pupil, 34 (40.48% ); corneal guttae, 31(36.9% ); glaucoma, 29(34.5% ); and pseudoexfoliation, 6(7.14% ). Intraoperatively, RAM was associated with overall surgical difficulty because of less working space in 59 eyes (70.24% ; OR, 63.7; 95% CI, 18.3- 221; P < 0.001) compared with control groups I and II; uveal trauma in 12(14.28% ); Descemet’s detachment in 5 (5.95% ); and posterior capsule rupture in 2 (2.38% ). Postoperatively, RAM was associated with transient corneal edema in 63 eyes (75% ; OR, 9.0; 95% CI,

关键词：白内障手术后弹力层脱离角膜水肿后囊破裂小瞳孔前房深度角膜直径测径器鳞片样脱皮眼轴长度

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