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481例16岁以下面部皮肤病患者病因分析

中华流行病学杂志 2004年第11期25卷 957-957页

作者：卢洁王有为孙福中钟宣琼蔺敏四川省皮肤病性病防治研究所成都610031

面部皮肤病属常见病,临床表现为多样性.我们选择了2003年以来我院面部皮肤病患者的病例资料,进行回顾性分析,以了解16岁以下面部皮肤病患者的病因及分布情况.

关键词：面部皮肤病患者病因分析病例资料回顾性分析常见病临床表现多样性选择

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面部皮肤病患者应慎用哪些药物

求医问药 2007年第4期 17-页

作者：张揆一华中科技大学同济医学院

人的面部不仅血运丰富,而且许多部位(如鼻口三角区)的血管都与大脑相通。因此,面部皮肤病(如痤疮、脂溢性角化病)患者不可随意往脸上涂抹药物,否则可能会适得其反。下面就介绍几种不能用在面部的药物:

关键词：面部皮肤病光敏物质

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鼻部皮肤外科手术63例分析

北京大学学报（医学版） 2006年第5期38卷 519-521页

作者：李航杨淑霞王波北京大学第一医院皮肤性病科北京100034

目的:对63例鼻部皮肤外科手术病例进行回顾性研究,探讨鼻部皮肤外科手术病例的共性、特点。方法:应用SPSS10.0和SAS6.12统计软件进行分析。结果:患者平均年龄(46.92±18.63)岁,男女性别构成比相近。患基底细胞癌的病例最多(42.9%),色素... 详细信息

目的:对63例鼻部皮肤外科手术病例进行回顾性研究,探讨鼻部皮肤外科手术病例的共性、特点。方法:应用SPSS10.0和SAS6.12统计软件进行分析。结果:患者平均年龄(46.92±18.63)岁,男女性别构成比相近。患基底细胞癌的病例最多(42.9%),色素痣其次(38.1%),其余均为良性肿物。手术部位中鼻翼占52.4%,鼻梁占22.2%,鼻尖占15.9%,其余部位占9.5%。所有病例中,应用单纯闭合手术者占69.8%,应用到复杂成形技术的占30.2%。统计结果显示,单纯闭合与复杂成形修复在手术部位上的分布差异具有统计学意义,两者所对应的切口面积差异有统计学意义;皮肤恶性肿瘤与良性肿物在是否应用了复杂成形技术方面的差异有统计学意义。结论:对于发生于鼻部的皮肤恶性肿瘤及常见良性肿物除应用经典皮肤外科手段———Mohs显微外科手术完整切除肿瘤(或肿物)以外,熟练应用鼻部成形修复技术也非常重要。

关键词：面部皮肤病皮肤肿瘤修复外科手术

Facial dermatosis associated with Demodex:a case-control study

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第12期12卷 1008-1015页

作者： Ya-e ZHAO Yan PENG Xiang-lan WANG Li-ping WU Mei WANG Hu-ling YAN Sheng-xiang XIAO Department of Immunology and Pathogen Biology Xi ＇an Jiaotong University College of Medicine Xi ＇an 710061 China Xi ＇an Center for Disease Control and Prevention Xi ＇an 710054 China Department of Dermatology the Second Affiliated Hospital Xi ＇an Jiaotong University College of Medicine Xi ＇an 710004 China Department of Clinical Laboratory Chengdu First People＇s Hospital Chengdu 610041 China

Demodex has been considered to be related with multiple skin disorders,but controversy persists.In this case-control study,a survey was conducted with 860 dermatosis patients aged 12 to 84 years in Xi'an,China to identify the association between facial dermatosis and Demodex.Amongst the patients,539 suffered from facial dermatosis and 321 suffered from non-facial dermatosis.Demodex mites were sampled and examined using the skin pressurization method.Multivariate regression analysis was applied to analyze the association between facial dermatosis and Demodex infestation,and to identify the risk factors of Demodex infestation.The results showed that total detection rate of Demodex was 43.0%.Patients aged above 30 years had higher odds of Demodex infestation than those under 30 years.Compared to patients with neutral skin,patients with mixed,oily,or dry skin were more likely to be infested with Demodex(odds ratios(ORs) were 2.5,2.4,and 1.6,respectively).Moreover,Demodex infestation was found to be statistically associated with rosacea(OR=8.1),steroid-induced dermatitis(OR=2.7),seborrheic dermatitis(OR=2.2),and primary irritation dermatitis(OR=2.1).In particular,ORs calculated from the severe infestation(≥5 mites/cm2) rate were significantly higher than those of the total rate.Therefore,we concluded that Demodex is associated with rosacea,steroid-induced dermatitis,seborrheic dermatitis,and primary irritation dermatitis.The rate of severe infestation is found to be more correlated with various dermatosis than the total infestation rate.The risk factors of Demodex infestation,age,and skin types were identified.Our study also suggested that good hygiene practice might reduce the chances of demodicosis and Demodex infestation.

关键词：面部皮肤病 Demodex 群袭协会盒子控制学习变老

面部痤疮、湿疹、黄褐斑及日光皮炎皮肤屏障功能评价及其临床意义

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中华皮肤科杂志 2013年第1期46卷 29-32页

作者：邹菥何黎杨成庞勤昆明医科大学第一附属医院皮肤科云南省皮肤性病研究所650032

目的探讨痤疮、亚急性湿疹、黄褐斑及日光皮炎的皮肤屏障功能的差异。方法选损容性皮肤病300例，其中痤疮80例，亚急性湿疹80例；黄褐斑80例；日光皮炎60例。健康人60例为对照。运用德国Courage＋Khazaha公司的无创性皮肤生理功能测试... 详细信息

目的探讨痤疮、亚急性湿疹、黄褐斑及日光皮炎的皮肤屏障功能的差异。方法选损容性皮肤病300例，其中痤疮80例，亚急性湿疹80例；黄褐斑80例；日光皮炎60例。健康人60例为对照。运用德国Courage＋Khazaha公司的无创性皮肤生理功能测试仪，测量受试者面部皮肤的皮脂含量、角质层含水量和经表皮水分流失值（TWEL）。结果4种损容性皮肤病组与健康对照组相比，痤疮的皮脂含量及TWEL值较健康对照高，角质层含水量较健康对照低，差异有统计学意义（P〈0．01）。亚急性性湿疹、日光皮炎及黄褐斑的皮脂含量、角质层含水量均较健康对照组低，TWEL值均较健康对照高，差异有统计学意义（P〈0．01）。4种皮肤病组间进行比较，痤疮的皮脂含量比其他3组高，差异有统计学意义（P〈0．01），其余3组间皮脂含量差异无统计学意义（P〉0．05）；亚急性湿疹的角质层含水量比痤疮及黄褐斑低，差异有统计学意义（P〈0．01），与13光皮炎的角质层含水量相比，差异无统计学意义（P〉0．05）；日光皮炎的角质层含水量比痤疮及黄褐斑低，差异有统计学意义（P〈0．01）；痤疮的角质层含水量比黄褐斑低，差异有统计学意义（P〈0．01）；黄褐斑的TWEL值比其他3组低，差异有统计学意义（P〈0．01），其余3组TWEL值相比差异无统计学意义（P〉0.05）。结论4种损容性皮肤病皮肤屏障功能均存在损伤，提示恢复皮肤的屏障功能有助于治疗这4种损容性皮肤病。

关键词：面部皮肤病无创性皮肤测试皮肤,屏障

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中外玫瑰痤疮治疗指南与共识解读

中华皮肤科杂志 2018年第11期51卷 836-839页

作者：许阳骆丹南京医科大学第一附属医院皮肤科 210029

玫瑰痤疮是常见的慢性复发性炎症性面部皮肤病，表现为面中央隆凸部为主的阵发性潮红、持久性红斑及面颊、口周或鼻部毛细血管扩张、丘疹或丘脓疱疹，伴或不伴眼部症状以及主观症状如灼热、刺痛、干燥或瘙痒。

关键词：玫瑰痤疮治疗指南解读中外毛细血管扩张面部皮肤病主观症状眼部症状

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颜面部严重蜂窝织炎一例报告

天津医药 2010年第4期38卷 350-351,353页

作者：赵学群卫京平天津市第一中心医院感染科 300192

1病例报告患者女,37岁。主因间断发热6个月,颜面肿胀1个月,破溃2周,于2007年1月16日收入院。患者于6个月前无明显诱因出现发热,体温37℃～40℃,以午后、夜间为著,伴全身皮疹,纳差,辗转数家医院对症治疗,无明显好转且症状逐渐加重。1个... 详细信息

1病例报告患者女,37岁。主因间断发热6个月,颜面肿胀1个月,破溃2周,于2007年1月16日收入院。患者于6个月前无明显诱因出现发热,体温37℃～40℃,以午后、夜间为著,伴全身皮疹,纳差,辗转数家医院对症治疗,无明显好转且症状逐渐加重。1个月前出现口周及颜面部皮肤肿胀,2周前出现破溃、脱屑,高热,体温39℃～40℃。

关键词：蜂窝织炎面部皮肤病病例报告

Sociodemographic characteristics and risk factor analysis of Demodex infestation(Acari:Demodicidae)

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第12期12卷 998-1007页

作者： Ya-e ZHAO Na GUO Meng XUN Ji-ru XU Mei WANG Duo-lao WANG Department of Immunology and Pathogen Biology Xi ＇an Jiaotong University College of Medicine Xi ＇an 710061 China Department of Dermatology the Second Affiliated Hospital Xi ＇an Jiaotong University College of Medicine Xi ＂an 710004 China Department of Epidemiology and Population Health London School of Hygiene and Tropical Medicine London WCIE 7HT UK

To identify sociodemographic characteristics and risk factor of Demodex infestation,756 students aged 13-22 years in Xi'an,China were sampled for the school-based cross-sectional study.Demodex was examined using the cellophane tape method(CTP).The results showed that the total detection rate of Demodex was 67.6%.Logistic regression analysis revealed that five variables(gender,residence,sharing sanitary ware,frequency of face-wash per day,and use of facial cleanser) were found to be uncorrelated with Demodex infestation,whereas three variables(age,skin type,and skin disease) were found to be independent correlates.Students aged over 18 years had 22.1 times higher odds of Demodex infestation compared to those under 16 years and students aged 16-18 years also had 2.1 times higher odds compared to those aged 13-15 years.Odds of having a Demodex infestation for oily or mixed skin were 2.1 times those for dry or neutral skin.Students with a facial skin disease had 3.0 times higher odds of being infested with Demodex compared to those without.The inception rate of students with facial dermatoses increased in parallel with increasing mite count.The inception rates were 21.3%,40.7%,59.2%,and 67.7% in the negative,mild,moderate,and severe infestation groups,respectively(χ2=60.6,P<0.001).Specifically,the amount of infested mites and inception rate of acne vulgaris were positively correlated(R2=0.57,moderate infestation odds ratio(OR)=7.1,severe infestation OR=10.3).It was concluded that Demodex prevalence increases with age,and Demodex presents in nearly all adult human.Sebaceous hyperplasia with oily or mixed skin seems to favour Demodex proliferation.Demodex infestation could be associated with acne vulgaris.The CTP is a good sampling method for studies of Demodex prevalence.

关键词：学生 Demodex 群袭 Sociodemographic 特征风险因素逻辑回归分析面部皮肤病

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面部反复发生丘疹、脓疱

中华皮肤科杂志 1990年第1期23卷 67-68页

作者：李学熹中华医学会浙江分会皮肤科学会

病历摘要:患者男,43岁。1985年5月始,先自额及颊部生小红丘疹及丘脓疱疹,渐向外呈环或弧形扩大,可融成大片。有中度痒感。损害发展到一定范围后能自消,但反复发生不已。曾多次被诊断为面癣、湿疹及毛囊虫皮炎等,并按诸上症多次治疗均无

关键词：复发面部皮肤病脓疱病疹人类