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ADHF患者采用不同药物治疗后心脏LVEF、LVEDV、LVFS指标比较分析

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当代医学 2018年第15期24卷 167-169页

作者：毛向群景德镇第三人民医院江西景德镇333000

目的研究分析不同药物治疗急性失代偿性(ADHF)心力衰竭效果。方法抽取本院收治的96例急性失代偿性心力衰竭患者作为研究对象,研究时间为2015年4月～2017年4月,将96例患者随机分为两组,观察组48例和对照组48例,两组患者均进行常规西医治... 详细信息

目的研究分析不同药物治疗急性失代偿性(ADHF)心力衰竭效果。方法抽取本院收治的96例急性失代偿性心力衰竭患者作为研究对象,研究时间为2015年4月～2017年4月,将96例患者随机分为两组,观察组48例和对照组48例,两组患者均进行常规西医治疗,在此基础上,观察组患者应用参附注射液进行治疗,对比观察组与对照组的治疗效果。结果观察组患者左射血分数(LVEF)、左心室舒张末容积(LVEDV)、左心室短轴缩短率(LVFS)水平优于对照组,治疗有效率比对照组高,差异有统计学意义(P<0.05)。结论参附注射液治疗急性失代偿性心力衰竭效果较好,临床应用价值较高,值得临床推荐采纳。

关键词：参附注射液急性失代偿性心力衰竭左射血分数舒张末容积

2型肌强直性肌营养不良累及心肌和骨骼肌的31P-MRS和MRI定量研究

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世界核心医学期刊文摘（神经病学分册） 2005年第3期1卷 48-49页

作者： Schneider-Gold C. Beer M. Kstler H. 袁海峰

In myotonic dystrophy type 2 (DM2/PROMM), cardiac muscle involvement is usuall y more benign than in DM1, but clinically severe cardiomyopathy has been reporte d in some patients. Using a novel method of magnetic resonance spectroscopy (MRS ), we examined the left ventricular myocardium and the left gastrocnemius muscle in 11 unselected DM2/ PROMM patients without overt cardiac disease. Data on car diac morphology and function were obtained by gradient echo two dimensional cin e magnetic resonance imaging (MRI); no significant differences were found betwee n DM2 patients and healthy controls, but using a median split approach older pat ients showed mildly increased left ventricular (LV) volumes, i.e., 59%increase of end systolic volume index (ESVI) and 35%increase of enddiastolic volume ind ex (EDVI), and an increase of LV mass (26%). On cardiac MRS, DM2/PROMM patients showed a reduction of phosphocreatine (PCr) and adenosine triphosphate (ATP) by 25 and 20%compared to matched healthy controls. No significant differences wer e found between younger and older patients. In skeletal muscle of the DM2 patien ts, no significant decrease of PCr and ATP concentrations was found. However, in older patients, who commonly show overt hip flexor muscle weakness, we observed reduced values for PCr and ATP. Our MRS and MRI findings reveal evidence for su bclinical cardiomyopathy in DM2/PROMM patients without overt heart disease. Futu re prospective studies are needed to clarify the risk of developing overt cardia c disease in DM2 and to define prognostic factors.

关键词：肌营养不良肌强直 MRI P-MRS 定量研究收缩末容积舒张末容积左心室质量梯度回波心室肌

心脏MRI检查孤立性单支肺静脉异位连接的生理学特征

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世界核心医学期刊文摘（心脏病学分册） 2006年第11期2卷 38-38页

作者： Dyme J.L. Prakash A. Printz B.F. J.C. Nielsen 黄浙勇 Division of Pediatric Cardiology Mount Sinai School of Medicine New York NY United States Dr.

The physiology of isolated partially anomalous pulmonary venous connection of a single pulmonary vein has yet to be fully characterized. This study assessed the magnitude of the left-to-right shunt and right ventricular(RV) dilation from a single anomalous pulmonary vein using cardiac magnetic resonance imaging. Subjects with >1 anomalous pulmonary vein or associated lesions, including atrial septal defects, were excluded. In the 6 subjects identified, the median pulmonary-to-systemic flow ratio was 1.55(range 1.3 to 1.6). The mean RV end-diastolic volume indexed to body surface area in the subjects was significantly larger than in a normal reference cohort(108±16 vs 78±18 cm3/m2, p=0.0009) and greater than the upper limit of normal in all 6 subjects. Older age did not correlate with increased magnitude of shunting(r=0.3, p=0.5), but increased age did correlate with RV end-diastolic volume indexed to body surface area(r=0.96, p=0.01). Isolated partially anomalous pulmonary venous connection with only 1 vein connecting anomalously results in a modest left-to-right shunt and mild RV dilation.

关键词：生理学特征左向右分流房间隔缺损舒张末容积循环血流量正常值上限异常肺静脉体表面积立性