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64排螺旋CT及多平面重建技术在肿瘤性肠梗阻诊断中的价值

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泰山医学院学报 2013年第1期34卷 45-46页

作者：袁杰庄永祥白晶刘玉磊于广义王兆峰泰安市第一人民医院山东泰安271000 泰安市山口中心卫生院山东泰安271000

目的探讨64排螺旋CT多平面重建技术诊断肿瘤性肠梗阻的价值。方法收集50例经手术证实的肿瘤性肠梗阻病例CT资料,采用MPR(multiplanar reconstruction)技术对CT原始数据进行冠、矢状位的图像重建,并分析其表现。与临床手术和病理结果进... 详细信息

目的探讨64排螺旋CT多平面重建技术诊断肿瘤性肠梗阻的价值。方法收集50例经手术证实的肿瘤性肠梗阻病例CT资料,采用MPR(multiplanar reconstruction)技术对CT原始数据进行冠、矢状位的图像重建,并分析其表现。与临床手术和病理结果进行对照研究。结果 64排CT对本研究中肿瘤性肠梗阻的诊断准确率100%(50/50),对肿瘤定位诊断准确率为100%(50/50),定性诊断准确率为96%(48/50)。结论 MSCT MPR技术是术前无创性诊断肿瘤性肠梗阻的重要方法,对引起梗阻的肿瘤的定位、定性准确性高,具有重要的临床意义。

关键词：肠梗阻肿瘤性体层摄影术 X线计算机多平面重建技术

正常及肿瘤性结肠粘膜中癌胚抗原与碳水化合物抗原的免疫组织化学研究

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中国肿瘤临床 1988年第4期 23-26+2页

作者：欧阳钦,Mogens Vilien, Vibeke Binder,Birgitte R Jubl,Lise G Larsen 华西医科大学附属第一医院胃肠内科哥本哈根大学赫里夫医院胃肠内科哥本哈根大学赫里夫医院胃肠内科哥本哈根大学赫里夫医院病理科哥本哈根大学赫里夫医院病理科

本文应用结肠癌、伴异型增生的结肠腺瘤及正常结肠粘膜组织的石蜡切片作间接法免疫过氧化酶染色,以测定一批肿瘤伴随抗原的抗体的肿瘤特异性。所用抗体包括:抗癌胚抗原(CEA)的多克隆抗体及单克隆抗体Mab3851、Mab27;抗蛋白质—碳水化合... 详细信息

本文应用结肠癌、伴异型增生的结肠腺瘤及正常结肠粘膜组织的石蜡切片作间接法免疫过氧化酶染色,以测定一批肿瘤伴随抗原的抗体的肿瘤特异性。所用抗体包括:抗癌胚抗原(CEA)的多克隆抗体及单克隆抗体Mab3851、Mab27;抗蛋白质—碳水化合物的单克隆抗体MabC216、MabC242;抗脂质—碳水化合物的单克隆抗体MabC50、MabC19-9。实验结果发现三个单克隆抗体(Mab3851、Mab27及MabC216)的肿瘤特异性与正常对照有显著性差异。其增高的染色频率也见于异型增生的粘膜。而MabC242则逊於前三者。抗CEA的多克隆抗体、单克隆抗体MabC50及Mab19-9无肿瘤特异性。结果表明前三个抗体在鉴别结肠粘膜的良恶性质上,尤其在识别癌前病变上,具有一定的参考价值。

关键词：结肠粘膜结肠腺瘤碳水化合物癌瘤糖类不典型增生异型增生单克隆抗体性差异癌胚抗原免疫组织化学肿瘤性

采用经阴道三维超声及加强多普勒血管造影测量受刺激后和肿瘤性的子宫内膜容积及血管分布:测量者间的可重复性

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世界核心医学期刊文摘（妇产科学分册） 2006年第8期2卷 48-49页

作者： Mercé L.T. Alcá zar J.L. Engels V. 李奎 International Ruber Hospital Enrique Leyra 17 28029- Madrid Spain

Objectives. To assess intraobserver reproducibility of the endometrial volume (EV) and 3D power Doppler indices (vascularization index, VI; flow index, FI; and vascularization flow index, VFI) of the endometrium and subendometrial area using three- dimensional power Doppler angiography (3D- PDA). Methods. Twenty- five women on the hCG day after controlled ovarian stimulation and 15 patients presenting with uterine bleeding and suspicious endometrial thickening (10 endometrial cancers and 5 endometrial hyperplasias) were scanned. Eighty volume data sets were analyzed using the VOCAL imaging program. EV and VI, FI and VFI of the endometrium and subendometrium (5 mm shell) were manually calculated in the longitudinal and coronal planes with 15° and 9° rotation steps. Intraclass correlation coefficient (ICC) and 95% confidence intervals were used to assess reliability. Results. EV measurements were highly reproducible (ICC ≥ 0.97) without significant differences between planes and rotation steps. Endometrial and subendometrial VI, FI, and VFI presented ICCs above 0.90 with the exception of the subendometrial FI (ICC ≥ 0.80). There were no significant differences according to measurement plane and rotation step except for subendometrial VFI. Nevertheless, 3D power Doppler indices calculated in the coronal plane and 9° rotation step obtained the highest ICC. ICCs for 3D-PDA indices from the tumoral endometria were significantly higher than those calculated from the stimulated endometria. Conclusions. Endometrial volume and endometrial and subendometrial 3D power Doppler indices have an acceptable reproducibility, significantly higher in tumoral endometria. The reliability of measurements does not seem to be significantly influenced by the rotation plane and degrees of rotation. These results support that 3D- PDA and VOCAL are reliable methods to evaluate the physiological and pathological changes of the endometrium.

关键词：子宫内膜经阴道三维超声血管分布肿瘤性血管造影可重复性测量者控制性超排卵血管化子宫出

结核性与肿瘤性胸腔积液中TNF和IL-8含量的研究

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苏州医学院学报 1999年第2期19卷 130-130页

作者：张占英白金荣白艳艳韩晓枫朱固张澜生苏州医学院 215007

12例结核性胸膜炎TNF和IL-8的含量显著高于12例肿瘤性胸腔积液。进一步阐明迟发型变态反应的结核性胸水与免疫反应减弱的肿瘤性胸水局部免疫的不同机制。

关键词：结核性肿瘤性 TNF IL-8 胸腔积液

合并肌无力综合征和副肿瘤性天疱疮的胸腺瘤1例报道

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全科医学临床与教育 2017年第6期15卷 688-689页

作者：熊静孙秀玲韩剑虹昆明医科大学第二附属医院神经内科云南昆明650101

肌无力综合征（lambert-eaton syndrome,LEMS）是一种累及神经肌肉接头,突触前膜乙酰胆碱释放部位的自身免疫性疾病,副肿瘤性天疱疮临床少见,是自身免疫性大泡性皮肤病,两者都属于副肿瘤综合征范畴。胸腺瘤与副肿瘤性自身免疫疾病相关... 详细信息

肌无力综合征（lambert-eaton syndrome,LEMS）是一种累及神经肌肉接头,突触前膜乙酰胆碱释放部位的自身免疫性疾病,副肿瘤性天疱疮临床少见,是自身免疫性大泡性皮肤病,两者都属于副肿瘤综合征范畴。胸腺瘤与副肿瘤性自身免疫疾病相关出现的频率最高。

关键词：胸腺瘤天疱疮肌无力肿瘤性自身免疫疾病神经肌肉接头综合征胸腺切除术乙酰胆碱罕见病例

1例伴发Castleman瘤副肿瘤性天疱疮病人的手术管理

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护理研究（上旬版） 2009年第S1期23卷 122-123页

作者：杨兰上海交通大学医学院附属瑞金医院 200025

在成年裸鼠上检查细胞株致肿瘤性的三种接种途径比较

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国外医学.生物制品分册 1981年第6期 283-284页

作者：叶正中

一般认为先天性无胸腺裸鼠是检查人类及非人类细胞株致肿瘤性的最敏感动物之一。通常采用皮下接种进行检查。最近有人将一些类淋巴母细胞株接种到成年裸鼠脑内,发现脑部非常有利于肿瘤生长。作者采用人结肠腺癌细胞株接种到成年裸鼠脑内... 详细信息

一般认为先天性无胸腺裸鼠是检查人类及非人类细胞株致肿瘤性的最敏感动物之一。通常采用皮下接种进行检查。最近有人将一些类淋巴母细胞株接种到成年裸鼠脑内,发现脑部非常有利于肿瘤生长。作者采用人结肠腺癌细胞株接种到成年裸鼠脑内,皮下和肌内,以比较不同途径对肿瘤形成的影响。

关键词：裸鼠细胞株肿瘤性接种途径成年

以扁平苔藓伴低分化B细胞淋巴瘤为临床特征的副肿瘤性天疱疮

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世界核心医学期刊文摘（皮肤病学分册） 2005年第9期1卷 11-12页

作者： Coelho S. Reis J.P. Tellechea O. 刘艳 Clnica de Dermatologia Hospital da Universidade P3000075 Coimbra Portugal Dr.

Background:Neoplasia-induced lichen planus is described as a cell-mediated reaction to unknown epithelial antigens. Para-neoplastic pemphigus (PNP), characterized by the presence of a specific array of autoantibodies, probably represents a different form of presentation of the same autoimmune syndrome where the mucocutaneous expression depends on the dominant pathologic mechanism. Methods:The authors report a case of PNP with predominant lichen planus-like lesions and review the relevant literature. We observed a 74-year-old female with vesico-bullous,erosive,target-shaped and flat papular lichenoid lesions on the lower legs, palms and soles, evolving for 3 weeks. Histopathology revealed a lichenoid dermatitis. Direct immunofluorescence showed C3 deposition around keratinocytes and epidermal IgG intranuclear deposition. Indirect immunofluorescence revealed circulating IgG with intercellular staining on rat bladder substrate. Immunoblotting demonstrated bands of 130, 190, 210 and 250 kDa antigens. A pararenal B cell lymphoma was found. Results:Oral corticotherapy with 40 mg prednisolone daily was initiated with a good cutaneous response. Four months later, cyclophosphamide (50 mg/day) was introduced because of a discrete enlargement of the pararenal mass. The patient died on the seventh month of follow up as a result of respiratory insufficiency. Conclusion:PNP has different forms of presentation and the lack of a consensus a bout diagnostic criteria may contribute to underdiagnosed cases. Advances on the knowledge of the sensitivity and specificity of diagnostic criteria have allowed a better accuracy of diagnosis.

关键词： B细胞淋巴瘤扁平苔藓肿瘤性扁平丘疹大疱掌跖直接免疫荧光皮肤黏膜泼尼松龙间接免疫荧光

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大疱性副肿瘤性肢端角化症(法语)

世界核心医学期刊文摘（皮肤病学分册） 2006年第11期2卷 37-38页

作者： Schoeffler A. Sagot V. Marzin A. B. Labeille 李晓莉 Service de Dermatologie CHU Hpital Nord 42055 Saint-Etienne Cedex 2

Background. Bullous lesions of acral distribution are an uncommon finding in Bazex’s syndrome (acrokeratosis paraneoplastica). We report here one of these rare cases. Patients and methods. A 65 year-old-man, an alcoholic and a smoker, presented with characteristic lesions of Bazex’s acrokeratosis paraneoplastica associated with a right cervical lymph node mass. An epidermoid carcinoma of sinus piriformis was then discovered. The acrokeratosis lesions worsened and spread to the knees, elbows, trunk and genitalia, with an erosive aspect, pain in the extremities, and tender, hemorrhagic bullous lesions on the toes and sides of the feet. Histological examination of a biopsy sample showed a subepidermal blister with numerous eosinophilic leucocytes. Direct immunofluorescence showed C3 deposits on dermal capillaries and IgA and IgM on colloid bodies in the papillary dermis. Blood eosinophilia and high levels of IgE were noted. Indirect immunofluorescence was negative for anti-epidermal and anti-basement membrane antibodies. Radiation and chemotherapy for the neoplasia resulted in healing of the bullous lesions and almost complete disappearance of keratotic squamous lesions with residual hyperpigmentation. Discussion. Although bullous lesions are rare in Bazex’s syndrome (acrokeratosis paraneoplastica), they were noted as early as 1968 by Degos et al. These acral bullae mimic autoimmune bullous disease. An immunological reaction is thought to occur with antigens of the dermal-epidermal junction and eosinophils appear to be involved.

关键词：角化症大疱肿瘤性肢端真皮乳头层胶样小体角化性鳞屑直接免疫荧光法淋巴结群表皮样癌