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5%米诺地尔治疗女性型脱发效果及皮肤镜检结果

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影像研究与医学应用 2017年第8期1卷 224-225页

作者：李福昌山东省阳谷县人民医院皮肤性病科山东谷阳252300

目的:探讨5%米诺地尔治疗女性型脱发效果及皮肤镜检结果。方法:选择2015年9月—2016年12月本院收治的女性型脱发患者80例,分为两组,各40例,观察组使用5%米诺地尔,对照组口服螺内酯和养血生发胶囊,比较两组临床效果,并统计其Ludwig等级... 详细信息

目的:探讨5%米诺地尔治疗女性型脱发效果及皮肤镜检结果。方法:选择2015年9月—2016年12月本院收治的女性型脱发患者80例,分为两组,各40例,观察组使用5%米诺地尔,对照组口服螺内酯和养血生发胶囊,比较两组临床效果,并统计其Ludwig等级评分。结果:观察组有效率显著高于对照组(P<0.05),干预后观察组Ludwig等级评分高于对照组(P<0.05)。结论:针对女性型脱发使用5%米诺地尔治疗,其临床效果可靠,值得临床推广。

关键词： 5%米诺地尔女性型脱发皮肤镜检

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头皮黑色素瘤的皮肤镜检特征

世界核心医学期刊文摘（皮肤病学分册） 2005年第1期1卷 35-36页

作者： Zalaudek I Leinweber B. Soyer H.P. 刘超

There is a need to improve the early detection of melanoma of the scalp because it is characterized by a poorer prognosis compared with melanoma on other body *** is a useful tool for the early detection of melanoma but no previous reports on dermoscopic features of scalp melanoma have been *** describe the first case of melanoma of the scalp seen by dermoscopy exhibiting a multicomponent global pattern with atypical pigment network, irregular streaks, and regression *** contrast to the dermoscopic features usually seen in melanoma occurring on the face, the same morphologic type of pigment network usually seen in melanoma of the trunk was observed in our case of scalp melanoma.

关键词：黑色素瘤皮肤镜检早期检测成分构成文献报道分布形态

对“真性”无黑色素性黑色素瘤的皮肤镜检查:一项临床皮肤镜-病理的病例研究

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世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 58-59页

作者： De Giorgi V. Sestini S. Massi D. 刘艳 Department of Dermatology University of Florence Via degli Alfani 37 50121 Firenze Florence ItalyDr.

Completely amelanotic melanomas are rare and therefore often misclassified, with tragic consequences for patients. The use of dermoscopy for these lesions has not been validated yet because of the lack of studies that are based on large series. The analysis of the vascular pattern, which is often the only dermoscopic parameter to be seen, is therefore essential for a correct diagnosis. We present a case of “ true” amelanotic melanoma on the forehead of an 89- year- old man, which clinically mimicked squamous cell carcinoma. The patient was investigated both clinically and by focusing on his dermoscopic features and their pathologic correlates. The dermoscopic diagnostic algorithms routinely used for pigmented lesions are not helpful in diagnosing amelanotic melanoma because they are based on specific parameters not normally seen in amelanotic lesions. In the light of our experience, pattern analysis is the most reliable method for diagnosing these particular lesions correctly because it allows in- depth morphologic analysis of the few parameters found.

关键词：皮肤镜检病例研究色素性模式图鳞状细胞癌运算法形态学分析

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采用甲床和甲母质皮肤镜检查评价黑线甲

世界核心医学期刊文摘（皮肤病学分册） 2006年第2期2卷 12-12页

作者： Hirata S.H. Yamada S. Almeida F.A. Rua Taquarussu 245 S?ao Paulo- SP Cep: 04346- 040 Brazil

Melanonychia striata represents a diagnostic dilemma for dermatologists. The use of dermoscopy to assess the nail has advantages over clinical examination. However, when compared to skin lesions, it gives fewer details. We describe two cases of melanonychia striata submitted to dermoscopic examination of the nail bed and matrix. This is a new procedure that enables observing dermoscopic characteristics that are not visualized in the nail plate, thus, providing additional information.

关键词：甲母质皮肤镜检甲床

移植后发疹性黑色素细胞痣在停止免疫抑制治疗后消退:临床及皮肤镜检查

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世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 58-58页

作者： Piaserico S. Alaibac M. Fortina A.B.Peserico A. 刘艳 Unit of Dermatology Department of Medical and Surgical SciencesUniversity of PadovaVia Cesare Battisti 206 35128 Padova ItalyDr.

Excess melanocytic nevi have been reported in several groups of immunosuppressed patients, including organ transplant recipients. We report the case of a 16- year- old transplant recipient whose post- transplant melanocytic nevi decreased in size and color after graft rejection and interruption of immunosuppressive therapy. This case may represent a visual example of an effective immunosurveillance system against melanocytic nevi.

关键词：皮肤镜检黑色素细胞发疹免疫抑制治疗器官移植受者免疫监视移植排斥

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博温病(Bowen病)的皮肤镜检查

世界核心医学期刊文摘（皮肤病学分册） 2005年第2期1卷 54-54页

作者： Bugatti L. Filosa G. De Angelis R. 张宪旗 Unita Operativa di Dermatologia Ospedale 'A. Murri' Via dei Colli 52 60035 Jesi Italy

Background. In the literature no specific dermoscopic criteria have been described for the diagnosis of Bowen’s disease (BD). Objective/aim. To assess the morphological findings of BD seen under dermoscopic observation. Methods. Clinical and dermoscopic images of 14 patients affected by BD with various amount of pigmentation were obtained by means of Heine Dermaphot. Dermoscopic images were analysed by experienced observers applying the modified pattern analysis. Results. The most frequently occurring dermoscopic features were found to be: multicomponent pattern (100%); atypical vascular structures (86.6%); absence of pigmented network (64.3%) or presence of pseudo-network (35.7%); irregular diffuse pigmentation or blotches of pigment (64.2%); irregularly distributed dots and globules (64.2%); focal/multifocal hypopigmentation (78.5%), scaly surface (64.2%) and haemorrages (26.6%). Conclusions. Dermoscopically, BD is mainly characterized by a multicomponent global pattern associated with a prominent vascular pattern (mainly dotted vessels) and a scaly surface. Although no specific dermoscopic criteria can be given for BD, epiluminescence can be a valuable aid in the diagnosis of such a mimicker lesion.

关键词： Bowen 博温病皮肤镜检色素网色素减退点状血管色素斑图像分析法海因血管结构

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Bowen病的皮肤镜检查

世界核心医学期刊文摘（皮肤病学分册） 2005年第1期1卷 3-3页

作者： Zalaudek I. Argenziano G. Leinweber B. 罗素菊冯义国 Department of Dermatology Second University of Naples Via S. Pansini 5 I-80131 Naples Italy Dr.

Background: Dermoscopy improves the diagnostic accuracy in pigmented skin lesions, but it is also useful in the evaluation of nonpigmented skin tumours as it allows the recognition of vascular structures that are not visible to the naked eye. Bowens disease (BD) or squamous cell carcinoma in situ is usually nonpigmented, but may also rarely be pigmented. Objective: To describe the dermoscopic features in a series of pigmented and nonpigmented BD. Methods: Dermoscopic images of 21 histopathologically proven BD were evaluated for the presence of various dermoscopic features. Each lesion was photographed using the Dermaphot (Heine Optotechnik, Herrsching, Germany), at 10-fold magnification, and the colour slides were scanned to digital format using a Kodak Photo CD system. Results: The majority of cases of BDrevealed a peculiar dermoscopic pattern characterized by glomerular vessels (90%) and a scaly surface (90%). In addition, in pigmented BD small brown globules regularly packed in a patchy distribution (90%), and structureless grey to brown pigmentation (80%) were observed. Conclusions: Dermoscopy can be helpful for diagnosing BD because of the presence of repetitive morphological findings such as glomerular vessels and a scaly surface. In pigmented BD, small brown globules and/or homogeneous pigmentation can be seen as well.

关键词： Bowen 皮肤镜检原位鳞状细胞癌皮肤肿瘤色素性组织病理学系统扫描血管结构无结构成片分布

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大疱性表皮松解症痣皮肤镜检的特殊图像

世界核心医学期刊文摘（皮肤病学分册） 2005年第10期1卷 28-28页

作者： Lanschuetzer C.M Emberger M Laimer M H. Hintner 罗素菊 Department of Dermatology Paracelsus Private Medical University Muellner Hauptstrasse 48 A-5020 Salzburg Austria

Background:Large, asymmetrical and irregularly pigmented naevi in patients with epidermolysis bullosa (EB) have been reported often to mimic cutaneous melanoma clinically. Objectives:As the biological course of these peculiar moles is benign, we assessed EB naevi with a dermatoscope to determine whether they could be reliably differentiated from cutaneous melanoma. Methods We evaluated digital dermoscopic images of 23 EB naevi from 11 patients with EBand analysed these pigmented lesions according to pattern analysis, ABCD rule of dermoscopy and the seven-point checklist. Results:Melanoma-associated dermoscopic criteria such as multicomponent pattern (20 of 23), atypical pigment network (17 of 23), irregular dots/globules (16 of 23), irregular pigmentation (22 of 23) and an atypical vascular pattern (seven of 23) were frequently seen in EB naevi. In contrast, other criteria frequently associated with melanoma progression, such as irregular streaks, blue-whitish veil, regression structures (bluewhitish areas) or black dots, were rarely seen. Most lesions gave false-positive results when the scores of the dermoscopic diagnostic algorithms were calculated. Conclusions:Recurring dermoscopic structures in EB naevi reveal a distinctive dermoscopic pattern of this recently defined entity. Although EB naevi represent an exception to dermoscopic diagnostic algorithms, their dermoscopic evaluation most often allows us to estimate their benign nature. Nevertheless, as an unequivocal discrimination from malignant melanoma in vivo is sometimes not possible, regular clinical follow up of EB naevi with histopathological evaluation of highly suspicious lesions is mandatory.

关键词：皮肤镜检黑色素瘤色素网色素痣色素性逐步解析法白色膜色素沉着色部假阳性结果

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3例误诊为汗孔角化症病人的临床资料分析

首都医科大学学报 2017年第5期38卷 658-660页

作者：孙瑞凤陈慧朱威连石首都医科大学宣武医院皮肤性病科北京100053

汗孔角化症（porokeratosis,PK）是一种慢性进行性角化性皮肤病,皮损呈环状结构,边界清楚,边缘呈堤状隆起,中央萎缩。近年来,随着人们对汗孔角化症的认识,通过临床表现即可做出诊断,但是也存在误诊的现象。本文总结并分析了3例曾被误诊... 详细信息

汗孔角化症（porokeratosis,PK）是一种慢性进行性角化性皮肤病,皮损呈环状结构,边界清楚,边缘呈堤状隆起,中央萎缩。近年来,随着人们对汗孔角化症的认识,通过临床表现即可做出诊断,但是也存在误诊的现象。本文总结并分析了3例曾被误诊为汗孔角化症病人的临床资料,以期提高临床诊断准确率。1临床资料病例1,女性,65岁,主诉双下肢散在环状皮疹20年。

关键词：汗孔角化症角化性皮肤病临床资料皮肤镜检环状结构灰泥角化病 appearance 临床诊断遗传性皮肤病鉴别诊断