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中国医院药学杂志 1990年第8期10卷 359-360页

作者：黄桢刘彩云郭军解放军153中心医院 450065

甲巯基咪唑(他巴唑)是治疗甲亢的常用药物。其含量测定方法,1985年版《中国药典》采用中和法,此法不仅取样量大,操作费时,且终点变化较为迟钝。本文试用紫外分光光度法测定结果与中和法基本一致。一。

关键词：分光光度法甲巯基咪唑含量

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大剂量服用甲巯基咪唑引起血压升高1例

医学争鸣 2002年第S1期 154-154页

作者：许晓莲张婕陕西武警总队医院药剂科陕西西安710054

1 临床资料赵某,女,50岁,家属,2001年由我院确诊为甲状腺功能亢进,长期服用甲巯基咪唑,病情基本稳定,每次服5mg·d-1。

关键词：甲巯基咪唑血压升高

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是慢性静止期脱发还是雄性秃发?

世界核心医学期刊文摘（皮肤病学分册） 2005年第4期1卷 35-36页

作者： Sinclair R. 刘超 R. Sinclair Department of Dermatology University of Melbourne St. Vincent’s Hospital 41 Victoria Parade Fitzroy Vic. 3065 Australia

A 16-year-old girl presented with a 12-month history of generalized hair shedding from the scalp. The onset of shedding coincided with the development of Hashimoto’s thyroiditis and iron deficiency. At the time of initial presentation, the Has himoto’s thyroiditis had been treated with Neo-Mercazole and she was euthyroid. Her iron stores were low, with a ferritin level of 13 μg/L. As she was vegetarian, oral iron replacement therapy was commenced without further investigation. On follow-up 6 months later, her iron stores were normal (ferritin, 36 μg/L),but the hair shedding had continued. On examination, there was a positive hair pull test from both the vertex of the scalp and the occipital scalp. There was mild bitemporal recession, but no widening of the central part, and she appeared to have a full, thick head of hair (Fig. 1). Additional investigations at that time revealed normal thyroid function and negative antinuclear antibody (ANA) and syphilis serology. She was on no medication other than Neo-Mercazole. Serum testosterone, dihydroepiandosterone sulphate(DHEAS) and sex hormone binding globulin (SHBG) were normal. Two 4-mm punch biopsies were taken from the vertex of the scalp; one was sectioned horizontally and the other vertically. The vertical section was unremarkable. On the horizontal section, there were 32 hair follicles in total, 30 of which were terminal hairs and two of which were vellus hairs. One hair was in telogen. The ratio of terminal to vellus hairs was 15 : 1. A diagnosis of chronic telogen effluvium was made. The condition was explained to the patient and she was reassured that chronic telogen effluvium is not a progressive condition and does not lead to baldness. No treatment was recommended. At follow-up 12 months later, the hair loss had obviously progressed and the patient was assessed as having Ludwig Stage 1 and rogenetic alopecia with widening of the central part (Fig. 2). Repeat blood tests showed normal iron studies, thyroid functi

关键词：慢性静止期脱发秃发甲巯基咪唑终毛毳毛梅毒血清学试验甲状腺功能正常中央区初次就诊桥本甲状腺炎

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甲状腺疾病

国外科技资料目录（医药卫生） 2002年第4期 72-73页

0213145 巴塞多病同位素治疗后再用甲巯基咪唑发生粒细胞缺乏1例[日]/佐佐木里香//诊と药.-2000,37(10).-30冀医情0213146 巴塞多病引发病窦机能不全综合征(SSS)2例(日]/竹内美征//诊と药.-2000,37(10).-31

关键词：巴塞多病粒细胞缺乏同位素治疗甲状腺疾病甲状腺功能减退机能不全综合征内美宇宙飞行甲巯基咪唑

3例甲疏基咪唑致粒细胞缺乏症治疗及护理体会

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西南军医 2000年第3期5卷 59-59页

作者：郭广兰谭友秀陈云霞成都军区总医院成都610083

甲巯基咪唑(他巴唑)是目前最常用于治疗甲状腺机能亢进(甲亢)的药物之一。但用该药造成白细胞减少症或粒细胞缺乏症(粒缺)时有发生。我科于1997年以来有3例甲亢病人在服用他巴唑治疗过程中出现粒缺,现将治疗过程及护理体会报告如下。1 ... 详细信息

甲巯基咪唑(他巴唑)是目前最常用于治疗甲状腺机能亢进(甲亢)的药物之一。但用该药造成白细胞减少症或粒细胞缺乏症(粒缺)时有发生。我科于1997年以来有3例甲亢病人在服用他巴唑治疗过程中出现粒缺,现将治疗过程及护理体会报告如下。1 临床资料 3例均为确诊的甲亢患者,男性1例,女性2例,年龄为24～35岁。因甲亢在门诊服用他巴唑治疗,剂量为20～30mg/天,用药时间在30～42天。在用药过程中患者未按医嘱定时来院检查血常规。

关键词：甲巯基咪唑粒细胞缺乏病护理体会