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16卷4期疑难病案讨论选登

实用妇产科杂志 2000年第6期16卷 336-338页

作者：王学裕闫世芳李江平杨秋兰杨青菊边文会刘冰陈惠娟成杰邵勇河北省中医院!河北石家庄050011 山西省运城市人民医院!山西运城044000 株洲市妇幼保健院!湖南株洲412008

1可能诊断:腹盆腔结核、渗出包块型2诊断依据与分析2.1一般状况:精神差,消瘦,轻度贫血貌,属于消耗性疾病无疑.

关键词：卵巢恶性肿瘤盆腔卵巢癌卵巢囊腺癌生殖器肿瘤妇科检查小结节影浆液性左上肺原发性腹膜癌盆壁包块抗痨治疗生殖器恶性肿瘤轻度贫血貌附件切除核异型子宫女生殖器

接种疫苗后淋巴细胞增生肉芽肿10例(法语)

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世界核心医学期刊文摘（皮肤病学分册） 2005年第5期1卷 48-49页

作者： Lafaye S. Authier F.-J. Fraitag S. J. Wechsler 刘艳 Département de Pathologie H.opital Henri Mondor 51 Ave. du Ma rechal Lattre Tassigny 94010 Creteil'France

Background. Few cases of cutaneous lymphocytic hyperplasia secondary to vaccin ation have been published, although such lesions are not rare. Patients and meth ods. We report a series of 10 cases registered between 1993 and 2003. Results. M ean age was 25. The clinical aspect was solitary or multiple subcutaneous nodule s, located on the arm, developing after a delay of 1 to 18 months after vaccinat ion. Histologic examination showed a lymphocytic infiltration of the subcutaneou s fat, with diffuse and/or follicular pattern, without nuclear atypia, the morph ological and immunohistochemical analysis of which revealed the benigh nature. I n all cases, there was fibrosis and granuloma composed of lymphocytes, plasma ce lls, eosinophils and macrophages with basophilic cytoplasm. Morin stain showed i ntralesional aluminium in the 6 investigated cases. Evolution was always benign, with no relapse following exeresis. Discussion. Cutaneous lymphocytic hyperplas ia secondary to vaccination has to be suspected in a young patient with subcutan eous nodules appearing at a vaccination site. Evidence of aluminium in the lesio ns supports the diagnosis and the hypothesis that aluminium in the vaccine excip ient might have a role in the onset of such lesions.

关键词：淋巴细胞增生免疫组化分析嗜酸性细胞组织学检查滤泡型核异型皮下结节皮下脂肪臂部肥大细胞

卵巢粘液性和浆液性边界瘤(55例临床病理分析)

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天津医药 1982年第5期 276-279页

作者：陈有仲卢于源天津市中心妇产科医院中国人民解放军第254医院

近年,注意到部分卵巢上皮瘤,无论组织形态或临床经过均位于良、恶之间。即形态介于分化良好和明显恶性之间,生物学行为对机体有潜在危险的良、恶之间的肿瘤。此组肿瘤往往较难确诊,因对其性质认识上有

关键词：粘液性浆液性卵巢上皮核异型边界

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一例原发性骨恶性纤维组织细胞瘤的诊断报告

西北国防医学杂志 1988年第3期 74-75页

作者：王生录刘亚平刘勃第五医院病理科第五医院病理科

原发性骨恶性纤维组织细胞瘤(以下简称:骨MFH)较少见,我科最近在活检中遇见1例,通过病理形态观察,对其诊断进行讨论。临床病历患者女性,50岁,右上肢疼痛不适40余天。查:右上肢皮肤无红肿,肩关节处有明显压痛,活动受限。x线拍片提示:... 详细信息

原发性骨恶性纤维组织细胞瘤(以下简称:骨MFH)较少见,我科最近在活检中遇见1例,通过病理形态观察,对其诊断进行讨论。临床病历患者女性,50岁,右上肢疼痛不适40余天。查:右上肢皮肤无红肿,肩关节处有明显压痛,活动受限。x线拍片提示:右肱骨上端恶性骨肿瘤可能性大。活检术中于肱骨上端见一约4×3cm的肿物,骨质破坏,中央与骨髓腔相通,内充灰白色瘤组织。病理检查灰黄色碎小软组织数块,其中含有骨组织,体积9×7×3.5cm~3。镜下:瘤组织由纤维母细胞、组织细胞组成,均显示核异型,有病理性核分裂。

关键词：肱骨上端恶性骨肿瘤核异型病理检查临床病历明显压痛骨组织形态观察诊断报告骨质破坏

1例肉瘤起源于皮肤和皮下透明血管型Castleman病

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世界核心医学期刊文摘（皮肤病学分册） 2005年第12期1卷 28-29页

作者： Kazakov D.V. Morrisson C. Plaza J.A. M. Michal 惠海英 Sikl' s Department of Pathology Charles University Medical Faculty HospitalAlej Svobody 80 304 60 Pilsen Czech Republic

We report on a case of a sarcoma arising in the hyaline- vascular variant of Castleman disease (HVCD) of the skin and subcutis. The patient was a 38- year- old man who clinically presented with a subcutaneous non- fixed cyst- like mass on his right shoulder with an unremarkable prior medical history. Histologic sections showed a biphasic tumor with numerous atretic lymphoid follicles located in the deep dermis and subcutis and a spindle- cell neoplasm mainly situated in the deep subcutis and adjacent soft tissue. The atretic lymphoid component fulfilled the criteria for HVCD, whereas the spindle- cell lesion showed all the criteria for sarcoma including nuclear atypia and frequent mitotic figures. The sarcomatous componentwas diffusely positive for fascin, nerve growth factor receptor, and CD34 with focal weak reactivity for CD21 and CNA.42. Stains for CD23, CD31, CD35, CD99, ALK- 1, SMA, ASMA, desmin, factor XIIIa,AE1- AE3, EMA, bcl- 2, S- 100, Melan- A,HMB- 45, Cam 5.2, and factor VIII were negative in the neoplastic spindle cells. No monoclonal population of lymphocyteswas detected andwe could not identify EBV or HHV- 8 virus by PCR. Electron microscopy of the sarcomatous component showed spindle cells with labyrinth- like invaginations of the nucleus and numerous long, slender, interwoven cytoplasmic processes. The sarcomatous component in this case is most consistent with a poorly differentiated follicular dendritic cell sarcoma based upon the morphologic and ultrastructural findings.

关键词： Castleman病血管型梭形细胞核异型真皮深层淋巴滤泡双相性组织学切片邻近软组织淋巴样

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何谓境界瘤?

人民军医 1989年第5期32卷 71-71页

作者：刘彤华协和医院病理科

境界瘤即交界瘤(borderline tumor),是指介于良性和恶性肿瘤之间的一种肿瘤。具有恶性肿瘤的某些特征,但预后较真正的恶性肿瘤为佳。常见的交界瘤如卵巢浆液性交界性肿瘤,其病理特点为上皮细胞增生,呈复层排列,增生的细胞可脱落成游离... 详细信息

境界瘤即交界瘤(borderline tumor),是指介于良性和恶性肿瘤之间的一种肿瘤。具有恶性肿瘤的某些特征,但预后较真正的恶性肿瘤为佳。常见的交界瘤如卵巢浆液性交界性肿瘤,其病理特点为上皮细胞增生,呈复层排列,增生的细胞可脱落成游离的细胞团,有一定程度的核异型,核分裂稍增多,但无间质浸润。临床上,交界性肿瘤虽可复发,甚至转移,但再次手术治疗效果好。协和医院统计58例卵巢浆液性交界性肿瘤,其5年及10年存活率分别为94%和88%。

关键词：交界瘤卵巢浆液性间质浸润核异型恶性瘤核分裂细胞团上皮细胞增生浆液性腺癌复层

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20例假性湿疣临床与病理分析

医学信息 1998年第5期 63-63页

作者：简小平邵阳市中心医院皮肤科!422000