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Recording of Monophasic Action Potentials in Swine Using a Modified-tip Platinum Ablation Catheter and Electroanatomical Mapping System(摘要 )

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海南医学 2002年第12期13卷 174-175页

作者： SHAO Wenliu SHIA Wenyuan Ole Kongstad S Bertil Olsson Department of Cardiology, First Affiliated Hospital of Dalian Medical University. University Hospital, Lund, Sweden Department of Cardiology First Affiliated Hospital of Dalian Medical University. University Hospital Lund Sweden

Objective:In this study, the feasibility to evaluate the global myocardial activation and repolarization sequence using the electroanatomical mapping system and MAP recording technique via the modified platinum catheter was explored in swine. Methods:Ten healthy pigs (50-55 kg) were anaesthetized with pentobarbital and catamine, intubated and ventilated. Four vascular accesses were obtained. A modified small tip ablation catheter (Navi-Star, Biosense Webster), the end surface of tip electrode was 0.81 mm 2 and 1 mm in diameter, was used for MAP recording. The MAP electrograms were recorded between the tip (exploring electrode) and the ring electrode proximal to the tip (indifferent electrode). The catheter was intentionally positioned perpendicular to endocardium with slight contact pressure to allow MAP recording with a satisfactory amplitude and morphology. All MAP recordings were performed during sinus ***:The MAP recordings were obtained from both right atrium and left ventricle in 9 pigs, while the right ventricle was mapped during the same procedure in 2. The MAP electrograms were recorded from both right and left atrium via a patent foramen ovale in 1 pig. Totally, the right atrium was mapped in all the 10 pigs, right ventricle in 2, left atrium in 1 and left ventricle in 9. The MAP electrograms were recorded from 733 sites of right atrium, 179 of right ventricle, 63 of left atrium and 517 of left ventricle. There were 62% of right and 54% left atrial MAPamp satisfied the earlier defined criteria of acceptable MAP, i.e., the MAPamp ≥ 3 mV in atrium, while 32% of right and 38% of left ventricular MAPamp were ≥ 10 mV. The mean MAPamp was 5.7±3.1 mV in right atrium, 12.4±2.5 mV in right ventricle, 4.5±1.9 mV in left atrium and 13.8±4 mV in left ventricle. The local activation was more distinctly and easily defined using MAP recordings with the computer-assisted manual determination, so were the end-of-repolarization points. The global activation and r

关键词：心电图 MAP 铂消融导管电生理学心肌激活

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