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Feasibility study of computed vs measured high b-value(1400 s/mm2) diffusion-weighted MR images of the prostate

World Journal of Radiology 2014年第6期6卷 374-380页

作者： Leonardo K bittencourt Ulrike I Attenberger Daniel Lima Ralph Strecker Andre de Oliveira Stefan O Schoenberg Emerson L Gasparetto Daniel Hausmann CDPI Ressonancia Magnética Avenida das Américas 4666 Barra da Tijuca RJ 22631-000 Brazil Institute of Clinical Radiology and Nuclear Medicine University of Heidelberg University Hospital Mannheim The-odor-Kutzer-Ufer 1-3 68167 Mannheim Germany Siemens Healthcare brazil Avenida Mutinga 3800 Jardim Santo Elias SP 05110-902 Brazil Siemens AG Healthcare Sector Henkestrasse127 D-91052 Erlangen Germany

AIM: To evaluate the impact of computed b = 1400 s/mm2(C-b1400) vs measured b = 1400 s/mm2(M-b1400) diffusion-weighted images(DWI) on lesion detection rate, image quality and quality of lesion demarcation using a modern 3T-MR system based on a small-field-of-view sequence(sFOV). METHODS: Thirty patients(PSA: 9.5 ± 8.7 ng/mL; 68 ± 12 years) referred for magnetic resonance imaging(MRI) of the prostate were enrolled in this study. All measurements were performed on a 3T MR *** DWI, a single-shot EPI diffusion sequence(b = 0, 100, 400, 800 s/mm2) was utilized. C-b1400 was cal-culated voxelwise from the ADC and diffusion images. Additionally, M-b1400 was acquired for evaluation and comparison. Lesion detection rate and maximum lesion diameters were obtained and compared. Image quality and quality of lesion demarcation were rated accord-ing to a 5-point Likert-type scale. Ratios of lesion-to-bladder as well as prostate-to-bladder signal intensity(SI) were calculated to estimate the signal-to-noise-ratio(SNR). RESULTS: Twenty-four lesions were detected on M-b1400 images and compared to C-b1400 images. C-b1400 detected three additional cancer suspicious lesions. Overall image quality was rated significantly better and SI ratios were significantly higher on C-b1400(2.3 ± 0.8 vs 3.1 ± 1.0, P between C- and M-b1400(P = 0.22). CONCLUSION: Combination of a high b-value extrap-olation and sFOV may contribute to increase diagnostic accuracy of DWI without an increase of acquisition time, which may be useful to guide targeted prostate biopsies and to improve quality of multiparametric MRI(mMRI) especially under economical aspects in a pri-vate practice setting.

关键词：前列腺癌症磁性的回声成像散开加权的成像超离频 b 值外推的 b 值

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