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In vitro antibacterial,alpha-amylase inhibition potential of three nudibranchs extracts from South East coast of India

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Journal of Coastal Life Medicine 2013年第3期 186-192页

作者： Giji Sadhasivam Arumugam Muthuvel Wanjale Mrunal Vitthal Abirami Pachaiyappan Mohan Kumar Balasubramanian Thangavel Centre of Advanced Study in Marine Biology Faculty of Marine Sciences Annamalai UniversityParangipettai-608502India

Objective:To study the antibacterial and antiamylase properties of methanol and acetone extracts of nudibranchs including Bursatella leachii(***),Kalinga ornata(***),Aplysia ***:Crude methanol and acetone extracts of sea slugs were tested for inhibition of fish bacterial pathogens'growth through disc diffusion *** activity was measured based on the formation of inhibition zone around the disc impregnated with crude ***α-amylase inhibitory effect was also measured *** chemical fingerprinting of the extract was recorded with HPTLC and ***:The solvent extracts of all the three sea slugs showed antibacterial *** maximum zone of inhibition(>15-20 mm)was recorded for methanol and acetone extracts of *** methanol extract of Aplysia *** 93%inhibition againstα-amylase,following by ***(methanol)70.6%and ***(methanol)49.03%inhibition *** acetone extracts didn't show any notable *** presence of free amino acids like lysine,aspartic acid,glutamic acid,arginine etc.,terpenoids and pigents were confirmed through HPTLC *** presence of siloxanes and propanoic acid were also revealed through ***:This study suggests that further scrutinisation of the ***,*** and Aplysia *** pave the way for development of antibacterial andα-amylase inhibitory agent for therapeutic application.

关键词： Antibacterial α-amylase inhibitory effect Pigents and terpenoids

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