检索结果-南通市图书馆

Exploring the interaction between the gut microbiota and cyclic adenosine monophosphate-protein kinase A signaling pathway:a potential therapeutic approach for neurodegenerative diseases

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3095-3112页

作者： Fengcheng Deng Dan Yang Lingxi Qing Yifei Chen Jilian Zou Meiling Jia Qian Wang Runda Jiang Lihua Huang College of Pharmacy Chengdu University of Traditional Chinese MedicineChengduSichuan ProvinceChina State Key Laboratory of Southwestern Chinese Medicine Resources Chengdu University of Traditional Chinese MedicineChengduSichuan ProvinceChina

The interaction between the gut microbiota and cyclic adenosine monophosphate(cAMP)-protein kinase A(PKA)signaling pathway in the host's central nervous system plays a crucial role in neurological diseases and enhances communication along the gut–brain *** gut microbiota influences the cAMP-PKA signaling pathway through its metabolites,which activates the vagus nerve and modulates the immune and neuroendocrine ***,alterations in the cAMP-PKA signaling pathway can affect the composition of the gut microbiota,creating a dynamic network of microbial-host *** reciprocal regulation affects neurodevelopment,neurotransmitter control,and behavioral traits,thus playing a role in the modulation of neurological *** coordinated activity of the gut microbiota and the cAMP-PKA signaling pathway regulates processes such as amyloid-β protein aggregation,mitochondrial dysfunction,abnormal energy metabolism,microglial activation,oxidative stress,and neurotransmitter release,which collectively influence the onset and progression of neurological *** study explores the complex interplay between the gut microbiota and cAMP-PKA signaling pathway,along with its implications for potential therapeutic interventions in neurological *** pharmacological research has shown that restoring the balance between gut flora and cAMP-PKA signaling pathway may improve outcomes in neurodegenerative diseases and emotional *** can be achieved through various methods such as dietary modifications,probiotic supplements,Chinese herbal extracts,combinations of Chinese herbs,and innovative dosage *** findings suggest that regulating the gut microbiota and cAMP-PKA signaling pathway may provide valuable evidence for developing novel therapeutic approaches for neurodegenerative diseases.

关键词： cyclic adenosine monophosphate emotional disorders gut microbiota neurodegenerative diseases neurological diseases protein kinase A reciprocal regulation signaling pathway strategy therapies

Design and characteristics of a new type laminar plasma torch for materials processing

在线全文

学校读者我要写书评

暂无评论

Plasma science and technology 2020年第1期22卷 24-32页

作者： Xiuquan CAO Lin CHEN School of Mechanical Engineering Sichuan University of Science and EngineeringZigong 643000People's Republic of China

Laminar plasma jet(LPJ)generated by laminar plasma torch(LPT)has a favorable temperature and velocity ***,it is superior to the turbulent plasma jet in material ***,most of the reported LPTs usually operate at a relatively low output power with a relatively low arc voltage and thermal efficiency,which limits its *** this context,this paper attempts to design a new type of high-power LPT with a relatively low arc current and a high thermal *** the first section,the design principle of the main components is studied and discussed in detail,and a new high-power LPT is ***,the experimental characteristics of the proposed high-power LPT are *** results reveal the following characteristics of the proposed LPT.(1)The max jet length of the proposed LPT reaches at 540 mm.(2)Its mean arc voltage is higher than 290 V when the LPT works with arc currents lower than 200 *** to an output power greater than 50 kW.(3)The mean thermal efficiency is higher than ***,the proposed LPT has been applied to spheroidize the aluminum oxide *** experiment results for the production of spherical powders show that the proposed LPT hits a good characteristic for material processing.

关键词： laminar plasma torch design principles high arc voltage with a low arc current spheroidisation

High catalytic performance of neodymium modified Co_(3)O_(4) for toluene oxidation

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第1期42卷 94-101,I0004页

作者： Yanqiong Hu Luyue Zhang Jianbei Zhang Yongjun Liu School of Architecture and Environment Sichuan UniversityChengdu610065China National Engineering Research Center for Flue Gas Desulfurization Chengdu610065China

Co-based catalysts are the most promising catalysts in catalytic oxidation of volatile organic compounds(VOCs).Precious metal doping is adopted to improve the catalytic activity of toluene on Co_(3)O_(4) catalysts,but greatly increases its cost along with *** is found that doping a small amount of rare earth(Ce,Pr,Sm and Nd)can dramatically promote the catalytic activity of Co_(3)O_(4).Especially,the Nd-doped Co_(3)O_(4) catalyst exhibits excellent catalytic activity with a toluene removal rate of 90% at 162.1℃,which is even better than that of Pt-doped Co_(3)O_(4).Compared with other rare earth metal doping,the Nd doping leads to a higher ratio of Co^(3+)/Co^(2+) and has more oxygen *** in situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS)experiments show that the lattice oxygen of Nd-Co sample can be utilized at a quite low temperature,while that of pure Co_(3)O_(4) cannot engage in oxidation reaction when the temperature is below 200℃,which visually demonstrates the main reason for the improved catalytic performance of Nd-Co catalyst.

关键词： Rare earth metals Nd Co_(3)O_(4) Toluene catalytic oxidation Oxygen vacancy Lattice oxygen

Ytterbium modified birnessite MnO_(2) for improving deep oxidation of toluene

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第4期42卷 668-675页

作者： Linjiang Sun Yan Cheng Yujie Liu Can Yi Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengdu611756China

A series of rare earth metals modified birnessite manganese dioxides(RE-Mn)was synthesized by hydrothermal method and their catalytic degradation of toluene was ***-Mn shows the best toluene oxidation activity with the conversion of T50%and T99%at 196 and 226℃,*** physiochemical characterizations identified that the high catalytic performance and excellent stability of Yb-Mn are mainly associated with its higher molar ratios of Mn^(4+)/Mn^(3+),more lattice oxygen(Olatt),and better mobility of surface adsorbed oxygen(O_(ads)).Moreover,it is confirmed that introduction of Yb into birnessite MnO_(2) facilitates the production of acetic acid at lower *** results can aid the design of high-efficiency manganese oxide catalysts for the catalytic combustion of VOCs.

关键词： Manganese oxide Rare earth metal doping Toluene Catalytic combustion

Succession law of Nd–Fe–B alloys with different coercivities

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2015年第9期34卷 657-661页

作者： Jie Tang Li-Rong Yang Lin Zhang Cheng-Fu Wei Yang Mei Yong-Ge Wen School of Chemistry and Chemical Engineering Mianyang Normal University Research Center of Laser Fusion China Academy of Engineering Physics

In order to establish a succession law of every phase in sintered Nd–Fe–B magnets marked as 38/38H/38SH/38 UH, four alloys of Nd33-xDyxAl0.7Nb0.6Cu0.1B1.05 Fe bal.(at%) were investigated after smelting processing, sintering processing, high-temperature tempering processing, and highand low-temperature tempering processing. It is found that the four phases: the Nd2Fe14B matrix phase, Nd-rich phase,B-rich phase, and defect phase can be inherited by means of the subsequent processing. These phases might have the special constitution and appearance in the different *** properties also have succession law. In every processing except smelting one, the values of remanence and maximum energy product hardly alter, but the value of coercive force increases gradually.

关键词： Nd–Fe–B alloy Phase Succession Magnetic property M

Generation of High-Repetition-Rate Pulse Trains through the Continuous-Wave Perturbed by a Weak Gaussian Pulse in an Optical Fiber

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2010年第1期27卷 128-131页

作者：钟先琼向安平 College of Optoelectronic technology Chengdu University of Information Technology Chengdu 610225

A new means of generating all-optically high-repetition-rate pulse trains is proposed and numerically demonstrated in an optical fiber. Our numerical simulations show that, due to the modulation instability effect, the initial continuous-wave with a weak optical pulse instead of conventional weak sinusoidal modulation imposed on it can gradually evolve into high-repetition-rate pulse trains. However, the generated pulse trains take on different features from the conventional case in terms of their widths, intensities, intervals, numbers, and pedestals.

关键词： Chinese climate network complex systems small world community

Multi-Distributed Speech Emotion Recognition Based on Mel Frequency Cepstogram and Parameter Transfer

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Electronics 2022年第1期31卷 155-167页

作者： LIN Long TAN Liang School of Computer science Sichuan Normal University Institute of Computing technology Chinese Academy of Sciences

Speech emotion recognition(SER) is the use of speech signals to estimate the state of emotion. At present, machine learning is one of the main research methods of SER, the test and training data S of traditional machine learning all have the same distribution and feature space, but the data of speech is accessed from different environments and devices, with different distribution characteristics in real life. Thus, the traditional machine learning method is applied to the poor performance of SER. This paper proposes a multi-distributed SER method based on Mel frequency cepstogram(MFCC) and parameter transfer. The method is based on single-layer long short-term memory(LSTM), pre-trained inceptionv3 network and multi-distribution corpus. The speech pre-processed MFCC is taken as the input of single-layer LSTM, and input to the pre-trained inception-v3 *** features are extracted through the pre-trained inception-v3 model. Then the features are sent to the newly defined the fully connected layer and classification layer,let the parameters of the fully connected layer be finetuned, finally get the classification result. The experiment proves that the method can effectively complete the classification of multi-distribution speech emotions and is more effective than the traditional machine learning framework of SER.

关键词： multidistribution corpus fully connected layer feature extraction speech signals machine learning method pre-trained inception-v3 model multidistributed speech emotion recognition pre-trained inception-v3 network feature space recurrent neural nets Mel frequency cepstogram parameter transfer single-layer LSTM speech pre-processed MFCC learning (artificial intelligence) speech recognition emotion recognition multidistributed SER method multidistribution speech emotions

ADVANCES IN TRANSFORMATION RATCHETING AND RATCHETING-FATIGUE INTERACTION OF NITI SHAPE MEMORY ALLOY

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2013年第3期26卷 221-236页

作者： Guozheng Kang School of Mechanics and Engineering Southwest Jiaotong University

The accumulation of inelastic deformation occurring in NiTi shape memory alloy under the stress-controlled cyclic loading condition is named transformation ratcheting, since it is mainly caused by the solid-solid transformation from austenite to martensite phase and vice versa. The transformation ratcheting and its effect on the fatigue life （i.e., transformation-fatigue interaction） are key issues that should be addressed in order to assess the fatigue of NiTi shape memory alloy more accurately. In this paper, the advances in the studies on the transformation ratcheting and rateheting-fatigue interaction of super-elastic NiTi shape memory alloy in recent years are reviewed： First, experimental observation of the uniaxial transformation ratcheting and ratcheting-fatigue interaction of super-elastic NiTi alloy under the stress-controlled cyclic loading conditions is treated, and the detrimental effect of transformation ratcheting on the fatigue life is addressed; Secondly, two types of cyclic constitutive models （i.e., a macroscopic phenomeno- logical model and a micromechanical one based on crystal plasticity） constructed to describe the transformation ratcheting of super-elastic NiTi alloy are discussed; Furthermore, an energy-based failure model is provided and dealt with by comparing its predicted fatigue lives with experimental ones; Finally, some suggestions about future work are made.

关键词： NiTi shape memory alloy transformation ratcheting constitutive model fatigue,failure model

Tea polyphenols increase the antioxidant status of laying hens fed diets with different levels of ageing corn

在线全文

学校读者我要写书评

暂无评论

Animal Nutrition 2021年第3期7卷 650-660页

作者： Ling Zhou Xuemei Ding Jianping Wang Shiping Bai Qiufeng Zeng Zuowei Su Yue Xuan Keying Zhang Institute of Animal Nutrition Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of EducationSichuan Agricultural University211 Huimin RoadWenjiangChengdu611130China

This study was conducted to evaluate the effects of ageing corn levels(stored for 4 years)with or without the supplementation of tea polyphenols(TPP)on the performance,egg quality and antioxidant status of laying hens.A total of 288 Lohmann commercial laying hens(63-week-old)were used under a 2×4 factorial arrangement with 4 levels of dietary ageing corn(0%,25%,50%,or 100%)and 2 levels of TPP(0 and 600 mg/kg)for 8 *** ageing corn linearly decreased(P<0.05)the egg production,serum total antioxidant capacity(T-AOC),liver glutathione peroxidase(GSH-Px)of laying hens,yolk index,yolk colour,1,1-diphenyl-2-picrylhydrazyl(DPPH)value and the reducing power value of egg yolk,but it linearly increased(P<0.05)the feed conversion rate,ovary malondialdehyde(MDA)content of laying hens,and the protein carbonyl content of egg *** polyphenol supplementation increased(P<0.05)the serum T-AOC,serum superoxide dismutase(SOD),liver SOD,liver GSH-Px,ovary SOD,GSH-Px,the expression of antioxidant-related genes of laying hens,albumen height,Haugh unit,DPPH value and the majority free amino acids of egg yolk,but it decreased(P<0.05)the serum MDA content of laying hens,MDA and protein carbonyl of egg *** conclusion,the ageing corn significantly reduced the perfor-mance,egg quality,antioxidant status and egg antioxidant capacity of laying hens,while TPP supple-mentation partially counteracted the adverse effects,especially antioxidant status and egg antioxidant capacity of laying hens.

关键词： Tea polyphenol Antioxidant capacity Laying hen Ageing corn