Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethra...
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Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety. In 2018, we issued the guideline “2018 Standard Edition”. However much new direct evidence has now emerged and this may change some of previous recommendations. The time is ripe to develop new evidence-based guidelines, so we formed a working group of clinical experts and methodologists. The steering group members posed 31 questions relevant to the management of TUPKP for BPH covering the following areas: questions relevant to the perioperative period (preoperative, intraoperative, and postoperative) of TUPKP in the treatment of BPH, postoperative complications and the level of surgeons’ surgical skill. We searched the literature for direct evidence on the management of TUPKP for BPH, and assessed its certainty generated recommendations using the grade criteria by the European Association of Urology. Recommendations were either strong or weak, or in the form of an ungraded consensus-based statement. Finally, we issued 36 statements. Among them, 23 carried strong recommendations, and 13 carried weak recommendations for the stated procedure. They covered questions relevant to the aforementioned three areas. The preoperative period for TUPKP in the treatment of BPH included indications and contraindications for TUPKP, precautions for preoperative preparation in patients with renal impairment and urinary tract infection due to urinary retention, and preoperative prophylactic use of antibiotics. Questions relevant to the intraoperative period incorporated surgical operation techniques and prevention and management of bladder explosion. The application to different
The water absorption and desorption processes of different types of lightweight aggregates were ***,the influences of pre-wetting lightweight aggregates on compressive strength,microhardness,phase composition,hydratio...
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The water absorption and desorption processes of different types of lightweight aggregates were ***,the influences of pre-wetting lightweight aggregates on compressive strength,microhardness,phase composition,hydration parameters and micromorphology of the cement pastes were *** results showed that the water absorption and desorption capacities of the lightweight aggregates increased with the decrease of the densification *** the addition of pre-wetting lightweight aggregates,the compressive strength of the cement pastes would ***,the enhancement effect was more obviously with the desorption capacity of pre-wetting lightweight aggregates ***,sample S1 with pre-wetting red-mud ceramisites had the highest compressive strength,of which increased to 49.4 MPa after 28 d curing *** reason is that mainly because the addition of pre-wetting lightweight aggregates can promote the generation of C–S–H gels in the interfacial zone,and the hydration degree of the interfacial zone increases with the water desorption of pre-wetting lightweight aggregates *** is contributed to optimize the microstructure to enhance microhardness of the interfacial zone,resulting in the compressive strength of the cement-based materials ***,the pre-wetting lightweight aggregates with high porosity and strength are the potential internal curing agents for high-strength lightweight concretes.
The aim of this investigation was to prepare geopolymeric precursor from vanadium tailing(VT)by thermal activation and *** activation,a homogeneous blend of VT and sodium hydroxide was calcinated at an elevated temper...
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The aim of this investigation was to prepare geopolymeric precursor from vanadium tailing(VT)by thermal activation and *** activation,a homogeneous blend of VT and sodium hydroxide was calcinated at an elevated temperature and then modified with metakaolin to produce a geopolymeric *** the thermal activation,the VT was corroded by sodium hydroxide and then sodium silicate formed on the particle *** water was added,the sodium silicate coating dissolved to release silicon species,which created an alkaline solution *** metakaolin then dissolved in the alkaline environment to generate aluminum species,which was followed by *** VT particles were connected by a gel produced during geopolymerization,which yielded a geopolymer with excellent mechanical *** investigation not only improves the feasibility of using geopolymer technology for large-scale and in-situ applications,but also promotes the utilization of VT and other silica-rich solid wastes.
Frequency diverse array(FDA)radar applies a tiny frequency offset across its adjacent transmitting array elements to generate a range-angle-dependent *** increased degrees-of-freedom(DOFs)in range domain can help impr...
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Frequency diverse array(FDA)radar applies a tiny frequency offset across its adjacent transmitting array elements to generate a range-angle-dependent *** increased degrees-of-freedom(DOFs)in range domain can help improve the performance of radar in target detection,localization,and clutter *** radar utilizes uncontrollable external signal as illuminator,which makes it difficult to apply traditional frequency diverse process ***,the third-party illuminator such as Orthogonal Frequency Division Multiplexing(OFDM)signal usually consists of several closely spaced modulated carriers,and it has been widely selected as the illuminator for passive radar in recent *** the orthogonality between even separated subcarriers,we propose a new frequency diverse process method by extracting and processing each subcarrier of received data independently and attempt to provide a range-angle dependent beampattern for OFDM passive *** results and real data analyses verify the superiority of frequency diversity process on the received data of OFDM passive radar.
The exploration of bifunctional electrocatalysts with high catalytic activity and long-term durability for low-temperature Zn-air batteries(ZABs)is an ongoing ***,quintet-shelled hollow spheres,P-doped multi-layer Co_...
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The exploration of bifunctional electrocatalysts with high catalytic activity and long-term durability for low-temperature Zn-air batteries(ZABs)is an ongoing ***,quintet-shelled hollow spheres,P-doped multi-layer Co_(3)O_(4)(PM-Co_(3)O_(4)),with enriched oxygen vacancies are prepared by thermally induced mass relocation and a simple phosphating *** advanced characterizations reveal P anion-induced effects on internal electronic structure and local coordination *** finite element method elucidates that the complex multi-layer spherical nanostructure is conducive to the transport and diffusion of OH-and O_(2).Benefiting from its unique structural features and abundant oxygen vacancies,the well-designed PM-Co_(3)O_(4) presents small reversible oxygen overpotential for catalyzing oxygen reduction/evolution ***,the fabricated low-temperature ZABs based on PM-Co_(3)O_(4) as air-cathode exhibit high power density(20.8 mW·cm^(-2))and long-term stability(over 600 cycles)at the ultra-low temperature of-40℃,outperforming state-of-art Pt/C+IrO_(2)-based ***,the dynamic evolution mechanism of cobalt oxide catalysts during ZAB operation is *** work provides a guideline to design efficient electrocatalysts with regulated electronic configurations and exquisite nano-/microstructures for ZABs under extreme working conditions.
The transport property and phase transition for a parallel triple dot device are studied by adopting Wilson's numerical renormalization group technique, focusing on the effects of level spacings between neighboring d...
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The transport property and phase transition for a parallel triple dot device are studied by adopting Wilson's numerical renormalization group technique, focusing on the effects of level spacings between neighboring dot sites. By keeping dot 2at the half-filled level and tuning the level differences, it is demonstrated that the system transits from local spin quadruplet to triplet and doublet sequently, and three kinds of Kondo peaks at the Fermi surface could be found, which are separated by two Kosterlitz–Thouless type quantum phase transitions and correspond to spin-3/2, spin-1, and spin-1/2 Kondo effect,respectively. To obtain a detailed understanding of these problems, the charge occupation, the spin–spin correlation, the transmission coefficient, and the temperature-dependent magnetic moment are shown, and necessary physical arguments are given.
Wheat stripe rust poses a marked threat to global wheat *** and effective disease severity assessments are crucial for disease resistance breeding and timely management of field *** this study,we propose a practical s...
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Wheat stripe rust poses a marked threat to global wheat *** and effective disease severity assessments are crucial for disease resistance breeding and timely management of field *** this study,we propose a practical solution using mobile-based deep learning and model-assisted ***-Pocket,a user-friendly mobile application developed based on deep learning models,accurately quantifies disease severity in wheat stripe rust leaf images,even under complex ***,StripeRust-Pocket facilitates image acquisition,result storage,organization,and *** underlying model employed by StripeRust-Pocket,called StripeRustNet,is a balanced lightweight 2-stage *** first stage utilizes MobileNetV2-DeepLabV3+for leaf segmentation,followed by ResNet50-DeepLabV3+in the second stage for lesion *** severity is estimated by calculating the ratio of the lesion pixel area to the leaf pixel *** achieves 98.65%mean intersection over union(MIoU)for leaf segmentation and 86.08%MIoU for lesion *** using an additional 100 field images demonstrated a mean correlation of over 0.964 with 3 expert visual *** address the challenges in manual labeling,we introduce a 2-stage labeling pipeline that combines model-assisted labeling,manual correction,and spatial *** apply this pipeline to our self-collected dataset,reducing the annotation time from 20 min to 3 min per *** method provides an efficient and practical solution for wheat stripe rust severity assessments,empowering wheat breeders and pathologists to implement timely disease *** also demonstrates how to address the"last mile"challenge of applying computer vision technology to plant phenomics.
Background:Adequate evaluation of degrees of liver cirrhosis is essential in surgical treatment of hepatocellular carcinoma(HCC)*** impact of the degrees of cirrhosis on prediction of post-hepatectomy liver failure(PH...
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Background:Adequate evaluation of degrees of liver cirrhosis is essential in surgical treatment of hepatocellular carcinoma(HCC)*** impact of the degrees of cirrhosis on prediction of post-hepatectomy liver failure(PHLF)remains poorly *** study aimed to construct and validate a combined pre-and intra-operative nomogram based on the degrees of cirrhosis in predicting PHLF in HCC patients using prospective multi-center’s ***:Consecutive HCC patients who underwent hepatectomy between May 18,2019 and Dec 19,2020 were enrolled at five tertiary *** cirrhotic severity scoring(CSS)and intra-operative direct liver stiffness measurement(DSM)were performed to correlate with the Laennec histopathological grading *** performances of the pre-operative nomogram and combined pre-and intra-operative nomogram in predicting PHLF were compared with conventional predictive models of ***:For 327 patients in this study,histopathological studies showed the rates of HCC patients with no,mild,moderate,and severe cirrhosis were 41.9%,29.1%,22.9%,and 6.1%,*** CSS or DSM was closely correlated with histopathological stages of ***-three(10.1%)patients developed *** 30-and 90-day mortality rates were 0.9%.Multivariate regression analysis showed four pre-operative variables[HBV-DNA level,ICG-R15,prothrombin time(PT),and CSS],and one intra-operative variable(DSM)to be independent risk factors of *** pre-operative nomogram was constructed based on these four pre-operative variables together with total *** combined pre-and intra-operative nomogram was constructed by adding the intra-operative *** pre-operative nomogram was better than the conventional models in predicting *** prediction was further improved with the combined pre-and intra-operative ***:The combined pre-and intra-operative nomogram further improved prediction of PHLF when compared with the pre-operat
This paper develops and analyzes interior penalty discontinuous Galerkin(IPDG)method by patch reconstruction technique for Helmholtz *** technique achieves high order approximation by locally solving a discrete least-...
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This paper develops and analyzes interior penalty discontinuous Galerkin(IPDG)method by patch reconstruction technique for Helmholtz *** technique achieves high order approximation by locally solving a discrete least-squares over a neighboring element *** prove a prior error estimates in the L 2 norm and energy *** each fixed wave number k,the accuracy and efficiency of the method up to order five with high-order *** examples are carried out to validate the theoretical results.
Patients with chronic liver diseases(CLDs)develop acute liver injury and/or acute decompensation under the attack of various precipitants and present with significantly elevated alanine aminotransferase and/or total b...
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Patients with chronic liver diseases(CLDs)develop acute liver injury and/or acute decompensation under the attack of various precipitants and present with significantly elevated alanine aminotransferase and/or total bilirubin levels,liver failure,or acute decompensation of liver cirrhosis,which is called acute-on-CLD(AoCLD).AoCLD accounts for the majority of patients hospitalized in the Department of Hepatology or Infectious *** is complicated by various clinical types,the severity of the disease,and may pose a high risk of *** date,the definition of AoCLD is still vague,and a consensus concept of the clinical classification is *** review aimed to define the concept and clinical types of AoCLD based on related studies and the literature.
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