检索结果-南通市图书馆

Heteroatom tuning in agarose derived carbon aerogel for enhanced potassium ion multiple energy storage

Carbon Energy 2024年第3期6卷 239-254页

作者： Kaijun Xie Xin Liu Haolin Li Long Fang Kai Xia Dongjiang Yang Yihui Zou Xiaodong Zhang State Key Laboratory of Bio-fibers and Eco-textiles Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological TextilesInstitute of Marine Biobased MaterialsCollege of Chemistry and Chemical EngineeringCollege of Environmental Science and EngineeringQingdao UniversityQingdaoChina

The incorporation of heteroatoms into carbon aerogels(CAs)can lead to structural distortions and changes in active sites due to their smaller size and electronegativity compared to pure ***,the evolution of the electronic structure from single-atom doping to heteroatom codoping in CAs has not yet been thoroughly investigated,and the impact of codoping on potassium ion(K+)storage and diffusion pathways as electrode material remains *** this study,experimental and theoretical simulations were conducted to demonstrate that heteroatom codoping,composed of multiple heteroatoms(O/N/B)with different properties,has the potential to improve the electrical properties and stability of CAs compared to single-atom *** states near the Fermi level have revealed that doping with O/N/B generates a greater number of active centers on adjacent carbon atoms than doping with O and O/N *** a result of synergy with enhanced wetting ability(contact angle of 9.26°)derived from amino groups and hierarchical porous structure,ON-CA has the most optimized adsorption capacity(−1.62 eV)and diffusion barrier(0.12 eV)of K^(+).The optimal pathway of K^(+)in ON-CA is along the carbon ring with N or O *** K^(+)storage material for supercapacitors and ion batteries,it shows an outstanding specific capacity and capacitance,electrochemical stability,and rate ***,the assembled symmetrical K^(+)supercapacitor demonstrates an energy density of 51.8 Wh kg^(−1),an ultrahigh power density of 443Wkg^(−1),and outstanding cycling stability(maintaining 83.3%after 10,000 cycles in 1M KPF6 organic electrolyte).This research provides valuable insights into the design of highperformance potassium ion storage materials.

关键词： agarose carbon aerogels O/N/B codoping potassium-ion battery potassium-ion supercapacitor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Functions and mechanisms of protein lysine butyrylation(Kbu):Therapeutic implications in human diseases

引用

Genes & Diseases 2023年第6期10卷 2479-2490页

作者： Qianqian Xue Yanyan Yang Hong Li Xiaoxin Li Lu Zou Tianxiang Li Huibo Ma Hongzhao Qi Jianxun Wang Tao Yu Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China Department of Immunology School of Basic MedicineQingdao UniversityQingdaoShandong 266021China Clinical Laboratory Central Laboratory.The Affiliated Qingdao Hiser Hospital of Qingdao UniversityQingdaoShandong 266000China Department of Vascular Surgery The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China Department of Cardiac Ultrasound The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China

Post-translational modifications(PTM)are covalent modifications of proteins or peptides caused by proteolytic cleavage or the attachment of moieties to one or more amino *** play essential roles in biological function and regulation and have been linked with several *** of protein acylation(Kac),a type of PTM,are known to induce epigenetic regulatory processes that promote various ***,an increasing number of studies focusing on acylation modifications are being ***(Kbu)is a new acylation process found in animals and *** has been recently linked to the onset and progression of several diseases,such as cancer,cardiovascular diseases,diabetes,and vascular ***,the mode of action of certain drugs used in the treatment of lymphoma and colon cancer is based on the regulation of butyrylation levels,suggesting that butyrylation may play a therapeutic role in these *** addition,butyrylation is also commonly involved in rice gene expression and thus plays an important role in the growth,development,and metabolism of *** tools and analytical methods that could be utilized for the prediction and detection of lysine butyrylation have also been *** study reviews the potential role of histone Kbu,as well as the mechanisms underlying this *** also summarizes various enzymes and analytical methods associated with Kbu,with the goal of providing new insights into the role of Kbu in gene regulation and diseases.

关键词： Butyrylation Gene regulation Histone Post-translational modification Target treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhanced charge extraction for all-inorganic perovskite solar cells by graphene oxide quantum dots modified TiO_(2)layer

引用

Frontiers of Chemical science and Engineering 2023年第5期17卷 516-524页

作者： Yili Liu Guoliang Che Weizhong Cui Beili Pang Qiong Sun Liyan Yu Lifeng Dong College of Materials science and Engineering Qingdao University of Science and TechnologyQingdao 266042China Department of Physics Hamline UniversitySt.PaulMN 55104USA

All-inorganic cesium lead bromide(CsPbBr_(3))perovskite solar cells have been attracting growing interest due to superior performance stability and low ***,low light absorbance and large charge recombination at TiO_(2)/CsPbBr_(3)interface or within CsPbBr_(3)film still prevent further performance ***,we report devices with high power conversion efficiency(9.16%)by introducing graphene oxide quantum dots(GOQDs)between TiO_(2)and perovskite *** recombination of interfacial radiation can be effectively restrained due to enhanced charge transfer *** with C-rich active sites can involve in crystallization and fill within the CsPbBr_(3)perovskite film as functional semiconductor *** work provides a promising strategy to optimize the crystallization process and boost charge extraction at the surface/interface optoelectronic properties of perovskites for high efficient and low-cost solar cells.

关键词： all inorganic perovskite solar cells graphene oxide quantum dots high performance stability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lactate metabolism in human health and disease

引用

Signal Transduction and Targeted Therapy 2022年第10期7卷 3687-3708页

作者： Xiaolu Li Yanyan Yang Bei Zhang Xiaotong Lin Xiuxiu Fu Yi An Yulin Zou Jian-Xun Wang Zhibin Wang Tao Yu Center for Regenerative Medicine Institute for Translational MedicineThe Affiliated Hospital of Qingdao University Department of Cardiac Ultrasound The Affiliated Hospital of Qingdao UniversityNo.16 Jiangsu RoadQingdao 266000China Department of Immunology School of Basic MedicineQingdao UniversityQingdao 266071China Department of Respiratory Medicine Qingdao Municipal HospitalQingdao 266011China Department of Cardiology The Affiliated Hospital of Qingdao UniversityNo.1677 Wutaishan RoadQingdao 266555China

The current understanding of lactate extends from its origins as a byproduct of glycolysis to its role in tumor metabolism,as identified by studies on the Warburg *** lactate shuttle hypothesis suggests that lactate plays an important role as a bridging signaling molecule that coordinates signaling among different cells,organs and *** is a posttranslational modification initially reported by Professor Yingming Zhao’s research group in *** studies confirmed that lactylation is a vital component of lactate function and is involved in tumor proliferation,neural excitation,inflammation and other biological *** indispensable substance for various physiological cellular functions,lactate plays a regulatory role in different aspects of energy metabolism and signal ***,a comprehensive review and summary of lactate is presented to clarify the role of lactate in disease and to provide a reference and direction for future *** review offers a systematic overview of lactate homeostasis and its roles in physiological and pathological processes,as well as a comprehensive overview of the effects of lactylation in various diseases,particularly inflammation and cancer.

关键词： metabolism inflammation organs

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CRISPR/Cas9 therapeutics:progress and prospects

引用

Signal Transduction and Targeted Therapy 2023年第2期8卷 558-580页

作者： Tianxiang Li Yanyan Yang Hongzhao Qi Weigang Cui Lin Zhang Xiuxiu Fu Xiangqin He Meixin Liu Pei-feng Li Tao Yu Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityNo.38 Dengzhou Road266021QingdaoPeople’s Republic of China Department of Immunology School of Basic MedicineQingdao University266021QingdaoPeople’s Republic of China Department of Cardiology People’s Hospital of RizhaoNo.126 Taian Road276827RizhaoPeople’s Republic of China Department of Microbiology Linyi Center for Disease Control and Prevention276000LinyiPeople’s Republic of China Department of Cardiac Ultrasound The Affiliated Hospital of Qingdao University266000QingdaoPeople’s Republic of China

Clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)gene-editing technology is the ideal tool of the future for treating diseases by permanently correcting deleterious base mutations or disrupting disease-causing genes with great precision and efficiency.A variety of efficient Cas9 variants and derivatives have been developed to cope with the complex genomic changes that occur during ***,strategies to effectively deliver the CRISPR system to diseased cells in vivo are currently lacking,and nonviral vectors with target recognition functions may be the focus of future *** and physiological changes resulting from disease onset are expected to serve as identifying factors for targeted delivery or targets for gene *** are both varied and complex,and the choice of appropriate gene-editing methods and delivery vectors for different diseases is ***,there are still many potential challenges identified when targeting delivery of CRISPR/Cas9 technology for disease *** paper reviews the current developments in three aspects,namely,gene-editing type,delivery vector,and disease ***,this paper summarizes successful examples of clinical trials and finally describes possible problems associated with current CRISPR applications.

关键词： CRISPR/Cas9 editing delivery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synchronization clusters located on epileptic onset zones in neocortical epilepsy

引用

Acta Epileptologica 2022年第4期5卷 233-241页

作者： Yanping Sun Yuqiang Song Hongjin Ren Haifang Zhu Yanning Wang Xiaoli Li Wenjing Yan Yuping Wang Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijing100053China Department of Neurology The Affiliated Hospital of Qingdao UniversityQingdao266003China Faculty of Information Engineering and Automation Kunming University of Science and TechnologyKunming650500China School of science Yanshan UniversityQinhuangdao066004China State Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal UniversityBeijing100875China

Background Brain function is thought to rely on complex interactions of dynamic neural systems,which depend on the integrity of structural and functional *** epilepsy is considered to result from excessive focal synchronization in the *** analysis of multichannel electrocorticography(ECoG)contributes to the understanding of and orientation of *** aim of this study was to explore the synchronization in multichannel ECoG recordings from patients with neocortical epilepsy and characterize neural activity inside and outside the onset *** Four patients with neocortical epilepsy,who became seizure-free for more than 1 year after surgery guided by ECoG monitoring,were included in this *** data recorded during pre-surgical evaluation were *** in phase and amplitude of different frequency bands between ECoG channels was analyzed using *** generated 100 surrogate data from the original ECoG data using Amplitude Adjusted Fourier Transform to calculate the enhanced *** relationship between synchronization characteristics and seizure onset zone was *** We found synchronization clusters in the 14–30 Hz and 30–80 Hz bands around the onset areas during both interictal and the beginning of ictal periods in all four *** The enhanced-synchronization clusters play a central role in epilepsy,and may activate the onset areas and contribute to the spreading of epileptiform activity.

关键词： Epilepsy Synchronization clusters ECoG Seizure onset areas

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2

引用

Chinese Medical Journal 2013年第10期126卷 1925-1929页

作者： ZHOU Shao-fei HU San-yuan MA Lei MIAO Lei MAO Wei-zheng Department of (Jeneral Surgery Qilu Hospital Shandong UniversityJinan Shandong 250012 China Department o1: General Surgery Qingdao Municipal HospitalQingdao Shandong 266071 China

Background The relationship between the presence of metalloproteinases and thyroid cancer remains unknown, and many controversies still exist in this field. The objective of this study was to investigate the correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metall0Proteinase-2. Methods The correlations were studied bY detecting the levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloProteinase-1, and tissue inhibitor of metalloproteinase-2 by enzyme-linked immunosorbant assay and reverse-transcription polymerase chain reaction in the peripheral blood of 30 patients with papillary thyroid carcinoma, 27 patients with benign thyroid disease, and 25 hea !hy vo!unteers. Results The leve!s of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2 in the peripheral blood of patients with papillary thyroid carcinoma were significantly higher than those in the peripheral blood of patients with benign thyroid disease and healthy volunteers （P 〈0.05）. However, there were no significant differences between patients with benign thyroid disease and healthy volunteers （P 〉0.05）. The accuracy of detection by both enzyme-linked immunosorbant assay and reverse-transcription polymerase chain reaction in the papillary thyroid cancer group was 83.33%. Conclusions The levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2 in the peripheral blood are helpful in identifying thyroid carcinoma and aid in preoperative assessment.

关键词： thyroid carcinoma matrix metalloproteinase-2 matrix metalloproteinase-9 tissue inhibitor of metalloproteinase-1 tissue inhibitor of metalloproteinase-2

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Linear polyketides produced by co-culture of Penicillium crustosum and Penicillium fellutanum

引用

Marine Life science & technology 2022年第2期4卷 237-244页

作者： Guihong Yu Peng Sun Reyilamu Aierken Chunxiao Sun Zhenzhen Zhang Qian Che Guojian Zhang Tianjiao Zhu Qianqun Gu Mingyu Li Dehai Li Key Laboratory of Marine Drugs Chinese Ministry of EducationSchool of Medicine and PharmacyOcean University of ChinaQingdao266003China Laboratory for Marine Drugs and Bioproducts of Pilot National Laboratory for Marine science and technology(qingdao) Qingdao266237China Fujian Provincial Key Laboratory of Innovative Drug Target Research School of Pharmaceutical ScienceXiamen UniversityXiamen361102China School of Life sciences Shandong Province Key Laboratory of Applied MycologyQingdao Agricultural UniversityQingdao266109China

Two new polyketides, penifellutins A (1) and B (2), possessing a 22 carbon linear skeleton, were isolated from a co-culture of the deep-sea-derived fungi Penicillium crustosum PRB-2 and Penicillium fellutanum HDN14-323. Meanwhile, two esterification products of 1, penifellutins C (3) and D (4), were obtained because compound 1 could be esterified spontaneously when stored in methanol. Their configurations were difficult to determine because of chiral central crowdedness, structural flexibility and instability. As such, we solved this issue by comprehensively using Mo2(OAc)4-based CD experiments, density functional theory calculation of 13C NMR, DP4 + probability analysis and many chemical reactions, including making acetonide derivative, Mosher’s method, PGME method, etc. Compounds 1 and 2 show obvious inhibitory activity on the liver hyperplasia of zebrafish larvae at a concentration of 10 μmol/L, while 3 and 4 show no activity, indicating that two carboxyls in the structure are important active sites.

关键词： Co-culture Polyketides Extraction and isolation Structure elucidation Antiproliferation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Self-healing polyamide reverse osmosis membranes with temperature-responsive intelligent nanocontainers for chlorine resistance

引用

化学科学与工程前沿:英文版 2023年第9期17卷 1183-1195页

作者： Qian Yang Lin Zhang Xiao Xie Qiong Sun Jianguang Feng Hongzhou Dong Na Song Liyan Yu Lifeng Dong College of Materials science and Engineering Qingdao University of Science and TechnologyQingdao266042China qingdao University of science&technology Analytical&Testing Center Qingdao266042China Department of Physics Hamline UniversitySt.Paul55104USA

Improving the performance of reverse osmosis membranes remains great challenge to ensure excellent NaCl rejection while maintaining high water permeability and chlorine resistance. Herein, temperature-responsive intelligent nanocontainers are designed and constructed to improve water permeability and chlorine resistance of polyamide membranes. The nanocontainer is synthesized by layer-by-layer self-assembly with silver nanoparticles as the core, sodium alginate and chitosan as the repair materials, and polyvinyl alcohol as the shell. When the polyamide layer is damaged by chlorine attack, the polyvinyl alcohol shell layer dissolves under temperature stimulation of 37 ℃, releasing inner sodium alginate and chitosan to repair broken amide bonds. The polyvinyl alcohol shell responds to temperature in line with actual operating environment, which can effectively synchronize the chlorination of membranes with temperature response and release inner materials to achieve self-healing properties. With adding temperature-responsive intelligent nanocontainers, the NaCl rejection of thin film composite membrane decreased by 15.64%, while that of thin film nanocomposite membrane decreased by only 8.35% after 9 chlorination cycles. Effective repair treatment and outstanding chlorine resistance as well as satisfactory stability suggest that temperature-responsive intelligent nanocontainer has great potential as membrane-doping material for the targeted repair of polyamide reverse osmosis membranes.

关键词： reverse osmosis nanocontainer self-healing chlorine resistance water permeability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

BIFURCATION OF THE NORTH EQUATORIAL CURRENT DERIVED FROM ALTIMETRY IN THE PACIFIC OCEAN

引用

Journal of Hydrodynamics 2006年第5期18卷 620-626页

作者： WANG Qing-ye HU Dun-xin Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China Graduate School of the Chinese Academy of sciences Beijing 100039 China

The gridded （1/3°＊1/3°） altimetry data from October 1992 through December 2004 were analyzed to study the seasonal and interannual variabilities of the bifurcation of the North Equatorial Current （NEC） at the surface in the western North Pacific Ocean. Calculations show that on annual average the bifurcation occurs at about 13.4°N at the surface. The geostrophic flow derived from Sea Surface Height （SSH） data shows that the southernmost latitude of the NEC bifurcation at the surface is about 12.9°N in June and the northernmost latitude is about 14.1°N in December. Correlation analyses between the bifurcation latitude and the Southern Oscillation Index （SOl） suggest that the bifurcation latitude is highly correlated with the E1 Nino/Southern Oscillation （ENSO） events. During the E1 Nino years the bifurcation of the NEC takes place at higher latitudes and vice versa.

关键词： bifurcation of the North Equatorial Current altimetry data Pacific Ocean North Equatorial Current (NEC),E1 Nino/Southern Oscillation (ENSO) events

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：