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Food Science and Human Wellness 2024年

作者： Quanbin Fu Xin Sun Lu Liu Hailong Jiang Geoffrey I.N.Waterhouse Shiyun Ai Rusong Zhao School of Chemical Sciences， The University of Auckland College of Chemistry and Material Science， shandong Agricultural University Qilu University of Technology (shandong Academy of Sciences)， shandong Analysis and Test Center， key Laboratory for Applied Technology of Sophisticated Analytical Instruments of shandong province College of Food Science and Engineering， shandong Agricultural University

Organophosphorus pesticides (OPPs) in foods pose a serious threat to human health， motivating the development of novel analytical methods for their rapid detection and quantification. A magnetic covalent organic framework (M-COF) adsorbent for the magnetic solid-phase extraction (MSPE) of OPPs from foods was reported. M-COF was synthesized by the Schiff base condensation reaction of 1，3，5-tris (4-aminophenyl)benzene and 4，4-biphenyldicarboxaldehyde on the surface of amino-functionalized magnetic nanoparticles. Density–functional theory (DFT) calculations showed that adsorption of OPPs onto the surface of M-COF involved hydrophobic effects， Van der Waals interactions， π–π interactions， halogen-N bonding， and hydrogen bonding. Combined with gas chromatography–mass spectrometry (GC–MS) technology， the MSPE method features low limits of detection for OPPs (0.002–0.015 μg/L)， good reproducibility (1.45%–6.14%)， wide linear detection range (0.01–1 μg/L， R≥ 0.9935)， and satisfactory recoveries (87.3%–110.4%). The method was successfully applied for the trace analysis of OPPs in spiked fruit juices.

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Apple polyphenol product， phlorizin or procyanidin B2， alleviates transplanted obese patient fecal microbiota-induced obesity in mice by modulating the gut microbiota and related phages

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Food Science and Human Wellness 2024年

作者： Wenhui Li Zunyang Song Xin Xia Xiaoyu Jiang Dongxiao Sun-Waterhouse Dapeng Li College of Food Science and Engineering， shandong Agricultural University， key Laboratory of Food Nutrition and Human Health in Universities of shandong

Apples are popular fruits worldwide and rich in phenolic compounds that can alleviate obesity and related metabolic diseases. However， the mechanisms underlying the anti-obesity actions of apple polyphenols (AP) like phlorizin (PZ) and procyanidin B2 (PB2) on transplanted obese patient fecal microbiota (TOPFM)-induced obesity and related syndromes have not yet been fully examined in vivo. Herein， a commercial AP product， PZ compound or PB2 compound was used to ameliorate TOPFM-induced obesity in mice. The results indicated that the AP， PZ or PB2 supplementation markedly alleviate TOPFM-induced obesity in mice through effectively suppressing body weight gain and fat accumulation， alleviating insulin resistance and liver inflammation， regulating gut microecology and lipid synthesis/metabolism， and improving gut barrier function and antioxidant capacity. The gut barrier function and integrity were improved through regulating the expression of intestinal pro-inflammatory cytokines， TNF-α， IL-1β and IL-6， and gut barrier function-related genes， ZO-1 and Occludin， and raising the GLP-2 level via increasing the contents of short-chain fatty acids (SCFAs). Interestingly， the AP， PZ or PB2 supplementation could significantly improve the production of SCFAs and restore the microbial community structure and diversity in mice with TOPFM-induced obesity， in particular， increased the abundance of Lachnospiraceae and Bifidobacteriaceaca possibly by inhibiting Blautia and Bifidobacterium phages. The influences of AP， PZ or PB2 on gut microorganisms and phases of the mice upon TOPFM were species-specific. This study was the first report on the ability of an AP， PZ or PB2 supplementation to promote the production of SCFAs by modulating gut microbiota possibly via regulating gut phages.

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Progress and Implications from Genetic Studies of Bipolar Disorder

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Neuroscience Bulletin 2024年第8期40卷 1160-1172页

作者： Lingzhuo Kong Yiqing Chen Yuting Shen Danhua Zhang Chen Wei Jianbo Lai Shaohua Hu Department of Psychiatry the First Affiliated HospitalZhejiang University School of MedicineHangzhou310003China The key Laboratory of Mental Disorder Management in Zhejiang province Hangzhou310003China Brain research Institute of Zhejiang University Hangzhou310003China Zhejiang Engineering Center for Mathematical Mental Health Hangzhou310003China Department of Neurobiology NHC and CAMS Key Laboratory of Medical NeurobiologySchool of Brain Science and Brian Medicineand MOE Frontier Science Center for Brain Science and Brain-machine IntegrationZhejiang University School of MedicineHangzhou310003China

With the advancements in gene sequencing technologies,including genome-wide association studies,polygenetic risk scores,and high-throughput sequencing,there has been a tremendous advantage in mapping a detailed blueprint for the genetic model of bipolar disorder(BD).To date,intriguing genetic clues have been identified to explain the development of BD,as well as the genetic association that might be applied for the development of susceptibility prediction and pharmacogenetic *** genes of BD,such as CACNA1C,ANK3,TRANK1,and CLOCK,have been found to be involved in various pathophysiological processes correlated with *** the specific roles of these genes have yet to be determined,genetic research on BD will help improve the prevention,therapeutics,and prognosis in clinical *** latest preclinical and clinical studies,and reviews of the genetics of BD,are analyzed in this review,aiming to summarize the progress in this intriguing field and to provide perspectives for individualized,precise,and effective clinical practice.

关键词： Bipolar disorder Genetics Risk gene Genome-wide association study Sequencing technology

Reinforced SnO_(2) tensile-strength and“buffer-spring”interfaces for efficient inorganic perovskite solar cells

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Carbon Energy 2024年第6期6卷 282-291页

作者： Yuanyuan Zhao Lei Gao Qiurui Wang Qiang Zhang Xiya Yang Jingwei Zhu Hao Huang Jialong Duan Qunwei Tang College of Mechanical and Electronic Engineering Shandong University of Science and TechnologyQingdaoChina Institute of New Energy Technology College of Information Science and TechnologyJinan UniversityGuangzhouChina College of Materials Science and Engineering Sichuan UniversityChengduChina Guangxi key Laboratory of Processing for Non-Ferrous Metals and Featured Materials School of ResourcesEnvironment and MaterialsGuangxi UniversityNanningChina Institute of Carbon Neutrality College of Chemical and Biological EngineeringShandong University of Science and TechnologyQingdaoChina

Suppressing nonradiative recombination and releasing residual strain areprerequisites to improving the efficiency and stability of perovskite solar cells(PSCs).Here,long-chain polyacrylic acid(PAA)is used to reinforce SnO_(2)film and passivate SnO_(2)defects,forming a structure similar to“reinforcedconcrete”with high tensile strength and fewer ***,PAA is also introduced to the SnO_(2)/perovskite interface as a“buffer spring”torelease residual strain,which also acts as a“dual-side passivation interlayer”to passivate the oxygen vacancies of SnO_(2)and Pb dangling bonds in *** a result,the best inorganic CsPbBr_(3)PSC achieves a championpower conversion efficiency of 10.83%with an ultrahigh open-circuit voltageof 1.674 *** unencapsulated PSC shows excellent stability under 80%relative humidity and 80℃over 120 days.

关键词： charge recombination defect passivation inorganic perovskite solar cells interfacial modification strain relaxation

Experimental and Numerical Evaluation of the Cavitation Performances of Self-Excited Oscillating Jets

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Fluid Dynamics & Materials Processing 2024年第8期20卷 1883-1901页

作者： Yuanyuan Zhao Fujian Zhao Guohui Li Wei Xu Xiuli Wang School of the Environment and Safety Engineering Jiangsu UniversityZhenjiang212013China research Center of Fluid Machinery Engineering and Technology Jiangsu UniversityZhenjiang212013China GongQing Institute of Science and Technology Jiujiang332020China School of Energy and Power Engineering Jiangsu UniversityZhenjiang212013China

Self-excited oscillating jets(SOJ)are used in several practical *** performances are significantly affected by structural parameters and the target *** this study,a geometric model of the SOJ nozzle accounting for multiple structural parameters is introduced,then the related cavitation performances and the optimal target distance are investigated using a Large-Eddy Simulation(LES)*** are also provided about an experiment,which was conducted to validate the simulation *** analyzing the evolution of the vapor volume fraction at the nozzle outlet,a discussion is presented about the effect of the aforementioned structural parameters on the cavitation performances and the target *** is shown that the distribution of cavitation clouds at the outlet of the SOJ nozzle displays a non-monotonic trend(first increasing,then decreasing).Under working conditions with an inlet pressure of 4 MPa,a SOJ nozzle outlet/inlet diameter ratio(D_(1)/D_(2))of 1.2,and a chamber diameter ratio(D/L)close to 1.8,the nozzle outlet cavitation performance attains a *** optimal structural parameters correspond to the optimal target distance,which is near 50 *** experiments have revealed that the SOJ nozzle with the above parameters displays a good cavitation erosion effect at the target distance of 50 mm,in satisfactory agreement with the numerical simulation results.

关键词： Self-excited oscillating nozzle cavitating jet target distant LES cavitation

Adjuvant camrelizumab plus apatinib in resected hepatocellular carcinoma with microvascular invasion:a multi-center real world study

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Hepatobiliary Surgery and Nutrition 2024年第4期13卷 616-631,I0022-I0024页

作者： Jingzhong Ouyang Yi Yang Yanzhao Zhou Xu Chang Zhengzheng Wang Qingjun Li Yu Tang Jianqiang Cai Jinxue Zhou Zhen Huang Hong Zhao Department of Hepatobiliary and Pancreatic Surgery The Affiliated Cancer Hospital of Zhengzhou University&Henan Cancer HospitalZhengzhouChina Department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina key Laboratory of Gene Editing Screening and research and Development(R&D)of Digestive System Tumor Drugs Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Interventional Therapy II Shandong Cancer Hospital and InstituteShandong First Medical University and Shandong Academy of Medical SciencesJinanChina Clinical Trials Center National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Background:It is well known that laparoscopic liver surgery can offer advantages over open liver surgery in selected ***,what type of procedures can benefit most from a laparoscopic approach has been investigated poorly thus *** aim of this study is thus to define the extent of advantages of laparoscopic over open liver surgery for lesions in the anterolateral(AL)and posterosuperior(PS)***:In this international multicentre retrospective cohort study,laparoscopic and open minor liver resections for lesions in the AL and PS segments were compared after propensity score *** differential benefit of laparoscopy over open liver surgery,calculated using bootstrap sampling,was compared between AL and PS resections and expressed as a Delta of the ***:After matching,3,040 AL and 2,336 PS resections were compared,encompassing open and laparoscopic procedures in a 1:1 *** and PS laparoscopic liver resections were more advantageous in comparison to open in terms of blood loss,transfusion rate,complications,and length of ***,AL resections benefitted more from laparoscopy than PS in terms of overall and severe complications(D-difference were 4.8%,P=0.046 and 3%,P=0.046)and blood loss(D-difference was 195 mL,P<0.001).Similar results were observed in the subset for high-volume centres,while in recent years no significant differences were found in the differential benefit between AL and PS ***:The advantage of laparoscopic over open liver surgery is greater in the AL segments than in the PS segments.

关键词： Liver neoplasms hepatectomy laparoscopic liver resection open liver resection

Three-Dimensional Sound Source Location Algorithm for Subsea Leakage Using Hydrophone

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China Ocean Engineering 2024年第2期38卷 326-337页

作者： LI Hao-jie CAI Bao-ping YUAN Xiao-bing KONG Xiang-di LIU Yong-hong Javed Akbar KHAN CHU Zheng-de YANG Chao TANG An-bang College of Mechanical and Electronic Engineering China University of PetroleumQingdao 266580China Shenzhen Urban Public Safety Technology Institute Shenzhen 518000China Institute of Hydrocarbon Recovery Universiti Teknologi PETRONASBandar Seri IskandarPerak Darul Ridzuan 32610Malaysia

Leakages from subsea oil and gas equipment cause substantial economic losses and damage to marine ecosystem,so it is essential to locate the source of the ***,due to the complexity and variability of the marine environment,the signals collected by hydrophone contain a variety of noises,which makes it challenging to extract useful signals for *** solve this problem,a hydrophone denoising algorithm is proposed based on variational modal decomposition(VMD)with grey wolf ***,the average envelope entropy is used as the fitness function of the grey wolf optimizer to find the optimal solution for the parameters K andα.Afterward,the VMD algorithm decomposes the original signal parameters to obtain the intrinsic mode functions(IMFs).Subsequently,the number of interrelationships between each IMF and the original signal was calculated,the threshold value was set,and the noise signal was removed to calculate the time difference using the valid signal obtained by ***,the arrival time difference is used to locate the origin of the *** localization accuracy of the method in finding leaks is investigated experimentally by constructing a simulated leak test rig,and the effectiveness and feasibility of the method are verified.

关键词： grey wolf optimizer variational modal decomposition mean envelope entropy correlation coefficient time difference of arrival

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research on Electromagnetic Wave Absorption Based on Electrospinning Technology

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Chinese Journal of Chemistry 2024年第7期42卷 777-789页

作者： Baoding Li Jing Qiao Yue Liu Haoyuan Tian Wei Liu Qilei Wu Zhou Wang Jiurong Liu Zhihui Zeng key Laboratoryfor Liquid-Solid StructuralEvolution and Processing of Materials Schoolof Materials Science and EngineeringShandong UniversityJinanShandong 250061China China North Industries Group 53rd research Institute JinanShandong 250000China School of Mechanical Engineering Shandong UniversityJinanShandong 250061China Institute of Crystal Materials State Key Laboratory of Crystal MaterialsShandong UniversityJinanShandong 250100China Shenzhen research Institute of shandong University ShenzhenGuangdong 518057China Science and Technology on Electromagnetic Compatibility Laboratory China Ship Development and Design CentreWuhanHubei 430064China suzhou research Institute of shandong University SuzhouJiangsu215123China

At present,in order to overcome electromagnetic interference and prevent electromagnetic harm,the research of new and efficient electromagnetic wave absorbing materials has become the research focus in the field of materials *** one-dimensional structure can promote the impedance matching and attenuation characteristics of the absorbing ***,as an effective method to prepare nanofibers with high length-diameter ratio,has been widely concerned because it is suitable for struc-tural design of various *** this paper,the research progress and absorption properties of nano-fiber materials prepared by electrospinning combined with different processes are introduced.

关键词： Electromagnetic wave(EMW)absorbing Electrospinning Nanofiber Impedance matching Nanocomposite

Combinatorial reasoning-based abnormal sensor recognition method for subsea production control system

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Petroleum Science 2024年第4期21卷 2758-2768页

作者： Rui Zhang Bao-Ping Cai Chao Yang Yu-Ming Zhou Yong-Hong Liu Xin-Yang Qi College of Mechanical and Electronic Engineering China University of Petroleum BGP Inc. China National Petroleum Corporation

The subsea production system is a vital equipment for offshore oil and gas production. The control system is one of the most important parts of it. Collecting and processing the signals of subsea sensors is the only way to judge whether the subsea production control system is normal. However, subsea sensors degrade rapidly due to harsh working environments and long service time. This leads to frequent false alarm incidents. A combinatorial reasoning-based abnormal sensor recognition method for subsea production control system is proposed. A combinatorial algorithm is proposed to group sensors. The long short-term memory network(LSTM) is used to establish a single inference model. A counting-based judging method is proposed to identify abnormal sensors. Field data from an offshore platform in the South China Sea is used to demonstrate the effect of the proposed method. The results show that the proposed method can identify the abnormal sensors effectively.

关键词： Abnormal sensor Combinatorial algorithm Fault identification Subsea production control system

Protein acetylation sites with complex-valued polynomial model

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Frontiers of Computer Science 2024年第3期18卷 217-226页

作者： Wenzheng BAO Bin YANG School of Information Engineering Xuzhou University of TechnologyXuzhou 221018China School of Information Science and Engineering Zaozhuang UniversityZaozhuang 277160China

Protein acetylation refers to a process of adding acetyl groups(CH3CO-)to lysine residues on protein *** one of the most commonly used protein post-translational modifications,lysine acetylation plays an important role in different *** our study,we developed a humanspecific method which uses a cascade classifier of complexvalued polynomial model(CVPM),combined with sequence and structural feature descriptors to solve the problem of imbalance between positive and negative *** gene expression programming and differential evolution are utilized to search the optimal CVPM *** also made a systematic and comprehensive analysis of the acetylation data and the prediction *** performances of our proposed method are 79.15%in Sp,78.17%in Sn,78.66%in ACC 78.76%in F1,and 0.5733 in MCC,which performs better than other state-of-the-art methods.

关键词： protein acetylation complex-valued polynomial model machine learning